Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens von Morgens, David W., Wainberg, Michael, Boyle, Evan A., Ursu, Oana, Araya, Carlos L., Tsui, C. Kimberly, Haney, Michael S., Hess, Gaelen T., Han, Kyuho, Jeng, Edwin E., Li, Amy, Snyder, Michael P., Greenleaf, William J., Kundaje, Anshul, Bassik, Michael C.

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HER2-Overexpressing/Amplified Breast Cancer as a Testing Ground for Antibody-Drug Conjugate Drug Development in Solid Tumors von Pegram, Mark D., Miles, David, Tsui, C. Kimberly, Zong, Yu

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Lipid homeostasis is essential for a maximal ER stress response von Garcia, Gilberto, Zhang, Hanlin, Moreno, Sophia, Tsui, C Kimberly, Webster, Brant Michael, Higuchi-Sanabria, Ryo, Dillin, Andrew

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CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity von Kramer, Nicholas J., Haney, Michael S., Morgens, David W., Jovičić, Ana, Couthouis, Julien, Li, Amy, Ousey, James, Ma, Rosanna, Bieri, Gregor, Tsui, C. Kimberly, Shi, Yingxiao, Hertz, Nicholas T., Tessier-Lavigne, Marc, Ichida, Justin K., Bassik, Michael C., Gitler, Aaron D.

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Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens von Haney, Michael S., Bohlen, Christopher J., Morgens, David W., Ousey, James A., Barkal, Amira A., Tsui, C. Kimberly, Ego, Braeden K., Levin, Roni, Kamber, Roarke A., Collins, Hannah, Tucker, Andrew, Li, Amy, Vorselen, Daan, Labitigan, Lorenzo, Crane, Emily, Boyle, Evan, Jiang, Lihua, Chan, Joanne, Rincón, Esther, Greenleaf, William J., Li, Billy, Snyder, Michael P., Weissman, Irving L., Theriot, Julie A., Collins, Sean R., Barres, Ben A., Bassik, Michael C.

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Measuring expression heterogeneity of single-cell cytoskeletal protein complexes von Vlassakis, Julea, Hansen, Louise L., Higuchi-Sanabria, Ryo, Zhou, Yun, Tsui, C. Kimberly, Dillin, Andrew, Huang, Haiyan, Herr, Amy E.

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Cell-type-specific labeling of synapses in vivo through synaptic tagging with recombination von Chen, Yi, Akin, Orkun, Nern, Aljoscha, Tsui, C Y Kimberly, Pecot, Matthew Y, Zipursky, S Lawrence

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Beyond the cell factory: Homeostatic regulation of and by the UPRER von Metcalf, Melissa G., Higuchi-Sanabria, Ryo, Garcia, Gilberto, Tsui, C. Kimberly, Dillin, Andrew

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CRISPR screens and lectin microarrays identify high mannose N-glycan regulators von Tsui, C. Kimberly, Twells, Nicholas, Durieux, Jenni, Doan, Emma, Woo, Jacqueline, Khosrojerdi, Noosha, Brooks, Janiya, Kulepa, Ayodeji, Webster, Brant, Mahal, Lara K., Dillin, Andrew

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Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms von Peng, Jing, Santiago, Ivan J, Ahn, Curie, Gur, Burak, Tsui, C Kimberly, Su, Zhixiao, Xu, Chundi, Karakhanyan, Aziz, Silies, Marion, Pecot, Matthew Y

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Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples von Hamilton, Jennifer R, Stahl, Elizabeth C, Tsuchida, Connor A, Lin-Shiao, Enrique, Tsui, C Kimberly, Pestal, Kathleen, Gildea, Holly K, Witkowsky, Lea B, Moehle, Erica A, McDevitt, Shana L, McElroy, Matthew, Keller, Amanda, Sylvain, Iman, Hirsh, Ariana, Ciling, Alison, Ehrenberg, Alexander J, Ringeisen, Bradley R, Huberty, Garth, Urnov, Fyodor D, Giannikopoulos, Petros, Doudna, Jennifer A

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Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins von Morgens, David W, Chan, Charlene, Kane, Andrew J, Weir, Nicholas R, Li, Amy, Dubreuil, Michael M, Tsui, C Kimberly, Hess, Gaelen T, Lavertu, Adam, Han, Kyuho, Polyakov, Nicole, Zhou, Jing, Handy, Emma L, Alabi, Philip, Dombroski, Amanda, Yao, David, Altman, Russ B, Sello, Jason K, Denic, Vladimir, Bassik, Michael C

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Brains and brawn: Stress-induced myokine abates nervous system aging von Tsui, Kimberly, Dishart, Julian G., Dillin, Andrew

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The germline coordinates mitokine signaling von Shen, Koning, Durieux, Jenni, Mena, Cesar G., Webster, Brant M., Tsui, C. Kimberly, Zhang, Hanlin, Joe, Larry, Berendzen, Kristen M., Dillin, Andrew

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Finding host targets for HIV therapy von Tsui, C Kimberly, Gupta, Amita, Bassik, Michael C

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CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity von Tsui, C. Kimberly, Barfield, Robyn M., Fischer, Curt R., Morgens, David W., Li, Amy, Smith, Benjamin A. H., Gray, Melissa Anne, Bertozzi, Carolyn R., Rabuka, David, Bassik, Michael C.

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The extracellular matrix integrates mitochondrial homeostasis von Zhang, Hanlin, Tsui, C. Kimberly, Garcia, Gilberto, Joe, Larry K., Wu, Haolun, Maruichi, Ayane, Fan, Wudi, Pandovski, Sentibel, Yoon, Peter H., Webster, Brant M., Durieux, Jenni, Frankino, Phillip A., Higuchi-Sanabria, Ryo, Dillin, Andrew

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CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells von Ruetz, Tyson J., Pogson, Angela N., Kashiwagi, Chloe M., Gagnon, Stephanie D., Morton, Bhek, Sun, Eric D., Na, Jeeyoon, Yeo, Robin W., Leeman, Dena S., Morgens, David W., Tsui, C. Kimberly, Li, Amy, Bassik, Michael C., Brunet, Anne

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Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples von Hamilton, Jennifer R., Stahl, Elizabeth C., Tsuchida, Connor A., Lin-Shiao, Enrique, Tsui, C. Kimberly, Pestal, Kathleen, Gildea, Holly K., Witkowsky, Lea B., Moehle, Erica A., McDevitt, Shana L., McElroy, Matthew, Keller, Amanda, Sylvain, Iman, Hirsh, Ariana, Ciling, Alison, Ehrenberg, Alexander J., Ringeisen, Bradley R., Huberty, Garth, Urnov, Fyodor D., Giannikopoulos, Petros, Doudna, Jennifer A.

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Large‐scale genetic screens identify BET‐1 as a cytoskeleton regulator promoting actin function and life span von Garcia, Gilberto, Bar‐Ziv, Raz, Averbukh, Maxim, Dasgupta, Nirmalya, Dutta, Naibedya, Zhang, Hanlin, Fan, Wudi, Moaddeli, Darius, Tsui, C. Kimberly, Castro Torres, Toni, Alcala, Athena, Moehle, Erica A., Hoang, Sally, Shalem, Ophir, Adams, Peter D., Thorwald, Max A., Higuchi‐Sanabria, Ryo

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