Amplification of EGFR Wild-Type Alleles in Non-Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors von Nukaga, Shigenari, Yasuda, Hiroyuki, Tsuchihara, Katsuya, Hamamoto, Junko, Masuzawa, Keita, Kawada, Ichiro, Naoki, Katsuhiko, Matsumoto, Shingo, Mimaki, Sachiyo, Ikemura, Shinnosuke, Goto, Koichi, Betsuyaku, Tomoko, Soejima, Kenzo

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Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung von Miyoshi, Tomohiro, Umemura, Shigeki, Matsumura, Yuki, Mimaki, Sachiyo, Tada, Satoshi, Makinoshima, Hideki, Ishii, Genichiro, Udagawa, Hibiki, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Aokage, Keiju, Hishida, Tomoyuki, Yoshida, Junji, Nagai, Kanji, Goto, Koichi, Tsuboi, Masahiro, Tsuchihara, Katsuya

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Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma von Makinoshima, Hideki, Takita, Masahiro, Matsumoto, Shingo, Yagishita, Atsushi, Owada, Satoshi, Esumi, Hiroyasu, Tsuchihara, Katsuya

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SCRUM‐Japan GI‐SCREEN and MONSTAR‐SCREEN: Path to the realization of biomarker‐guided precision oncology in advanced solid tumors von Nakamura, Yoshiaki, Fujisawa, Takao, Taniguchi, Hiroya, Bando, Hideaki, Okamoto, Wataru, Tsuchihara, Katsuya, Yoshino, Takayuki, Ohtsu, Atsushi

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RET fusion gene: Translation to personalized lung cancer therapy von Kohno, Takashi, Tsuta, Koji, Tsuchihara, Katsuya, Nakaoku, Takashi, Yoh, Kiyotaka, Goto, Koichi

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Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies von Nakamura, Yoshiaki, Taniguchi, Hiroya, Ikeda, Masafumi, Bando, Hideaki, Kato, Ken, Morizane, Chigusa, Esaki, Taito, Komatsu, Yoshito, Kawamoto, Yasuyuki, Takahashi, Naoki, Ueno, Makoto, Kagawa, Yoshinori, Nishina, Tomohiro, Kato, Takeshi, Yamamoto, Yoshiyuki, Furuse, Junji, Denda, Tadamichi, Kawakami, Hisato, Oki, Eiji, Nakajima, Takako, Nishida, Naohiro, Yamaguchi, Kensei, Yasui, Hisateru, Goto, Masahiro, Matsuhashi, Nobuhisa, Ohtsubo, Koushiro, Yamazaki, Kentaro, Tsuji, Akihito, Okamoto, Wataru, Tsuchihara, Katsuya, Yamanaka, Takeharu, Miki, Izumi, Sakamoto, Yasutoshi, Ichiki, Hiroko, Hata, Masayuki, Yamashita, Riu, Ohtsu, Atsushi, Odegaard, Justin I., Yoshino, Takayuki

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The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan von Sunami, Kuniko, Naito, Yoichi, Aimono, Eriko, Amano, Toraji, Ennishi, Daisuke, Kage, Hidenori, Kanai, Masashi, Komine, Keigo, Koyama, Takafumi, Maeda, Takahiro, Morita, Sachi, Sakai, Daisuke, Kohsaka, Shinji, Tsuchihara, Katsuya, Yoshino, Takayuki

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Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epider... von Makinoshima, Hideki, Takita, Masahiro, Saruwatari, Koichi, Umemura, Shigeki, Obata, Yuuki, Ishii, Genichiro, Matsumoto, Shingo, Sugiyama, Eri, Ochiai, Atsushi, Abe, Ryo, Goto, Koichi, Esumi, Hiroyasu, Tsuchihara, Katsuya

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Chronological improvement in precision oncology implementation in Japan von Sunami, Kuniko, Naito, Yoichi, Komine, Keigo, Amano, Toraji, Ennishi, Daisuke, Imai, Mitsuho, Kage, Hidenori, Kanai, Masashi, Kenmotsu, Hirotsugu, Koyama, Takafumi, Maeda, Takahiro, Morita, Sachi, Sakai, Daisuke, Kohsaka, Shinji, Tsuchihara, Katsuya, Saigusa, Yusuke, Yoshino, Takayuki

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Collagen type I induces EGFR‐TKI resistance in EGFR‐mutated cancer cells by mTOR activation through Akt‐independent pathway von Yamazaki, Shota, Higuchi, Youichi, Ishibashi, Masayuki, Hashimoto, Hiroko, Yasunaga, Masahiro, Matsumura, Yasuhiro, Tsuchihara, Katsuya, Tsuboi, Masahiro, Goto, Koichi, Ochiai, Atsushi, Ishii, Genichiro

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Hypoglycemic/hypoxic condition in vitro mimicking the tumor microenvironment markedly reduced the efficacy of anticancer drugs von Onozuka, Hiroko, Tsuchihara, Katsuya, Esumi, Hiroyasu

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SCRUM-Japan, a Nation-Wide Cancer Genome Screening and Patient Registry Program von KATSUYA TSUCHIHARA

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Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1) von Naito, Yoichi, Aburatani, Hiroyuki, Amano, Toraji, Baba, Eishi, Furukawa, Toru, Hayashida, Tetsu, Hiyama, Eiso, Ikeda, Sadakatsu, Kanai, Masashi, Kato, Motohiro, Kinoshita, Ichiro, Kiyota, Naomi, Kohno, Takashi, Kohsaka, Shinji, Komine, Keigo, Matsumura, Itaru, Miura, Yuji, Nakamura, Yoshiaki, Natsume, Atsushi, Nishio, Kazuto, Oda, Katsutoshi, Oda, Naoyuki, Okita, Natsuko, Oseto, Kumiko, Sunami, Kuniko, Takahashi, Hideaki, Takeda, Masayuki, Tashiro, Shimon, Toyooka, Shinichi, Ueno, Hideki, Yachida, Shinichi, Yoshino, Takayuki, Tsuchihara, Katsuya

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Vandetanib in patients with previously treated RET -rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial von Yoh, Kiyotaka, Dr, Seto, Takashi, MD, Satouchi, Miyako, MD, Nishio, Makoto, MD, Yamamoto, Noboru, MD, Murakami, Haruyasu, MD, Nogami, Naoyuki, MD, Matsumoto, Shingo, MD, Kohno, Takashi, PhD, Tsuta, Koji, Prof, Tsuchihara, Katsuya, MD, Ishii, Genichiro, MD, Nomura, Shogo, MSc, Sato, Akihiro, MD, Ohtsu, Atsushi, MD, Ohe, Yuichiro, MD, Goto, Koichi, MD

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Classification and characterization of alternative promoters in 26 lung adenocarcinoma cell lines von Hamaya, Yamato, Suzuki, Ayako, Suzuki, Yutaka, Tsuchihara, Katsuya, Yamashita, Riu

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Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines von Suzuki, Ayako, Makinoshima, Hideki, Wakaguri, Hiroyuki, Esumi, Hiroyasu, Sugano, Sumio, Kohno, Takashi, Tsuchihara, Katsuya, Suzuki, Yutaka

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Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment von Suzuki, Ayako, Matsushima, Koutatsu, Makinoshima, Hideki, Sugano, Sumio, Kohno, Takashi, Tsuchihara, Katsuya, Suzuki, Yutaka

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SCRUM-Japan, a Nation-Wide Cancer Genome Screening and Patient Registry Program: MD Anderson Cancer Center - Tokyo Oncology Consortium Sister Institution Memorial Symposium - Oncol... von TSUCHIHARA, KATSUYA

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Multistage carcinogenesis in occupational cholangiocarcinoma: the impact of clonal expansion and risk estimation von Watanabe, Masahiko, Haeno, Hiroshi, Mimaki, Sachiyo, Tsuchihara, Katsuya

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Phase I trial of GBS‐01 for advanced pancreatic cancer refractory to gemcitabine von Ikeda, Masafumi, Sato, Akihiro, Mochizuki, Nobuo, Toyosaki, Kayo, Miyoshi, Chika, Fujioka, Rumi, Mitsunaga, Shuichi, Ohno, Izumi, Hashimoto, Yusuke, Takahashi, Hideaki, Hasegawa, Hiromi, Nomura, Shogo, Takahashi, Ryuji, Yomoda, Satoshi, Tsuchihara, Katsuya, Kishino, Satoshi, Esumi, Hiroyasu

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