Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning von Coudray, Nicolas, Ocampo, Paolo Santiago, Sakellaropoulos, Theodore, Narula, Navneet, Snuderl, Matija, Fenyö, David, Moreira, Andre L., Razavian, Narges, Tsirigos, Aristotelis

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Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1 von Lignitto, Luca, LeBoeuf, Sarah E., Homer, Harrison, Jiang, Shaowen, Askenazi, Manor, Karakousi, Triantafyllia R., Pass, Harvey I., Bhutkar, Arjun J., Tsirigos, Aristotelis, Ueberheide, Beatrix, Sayin, Volkan I., Papagiannakopoulos, Thales, Pagano, Michele

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Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia von Trimarchi, Thomas, Bilal, Erhan, Ntziachristos, Panagiotis, Fabbri, Giulia, Dalla-Favera, Riccardo, Tsirigos, Aristotelis, Aifantis, Iannis

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The bone marrow microenvironment at single-cell resolution von Tikhonova, Anastasia N., Dolgalev, Igor, Hu, Hai, Sivaraj, Kishor K., Hoxha, Edlira, Cuesta-Domínguez, Álvaro, Pinho, Sandra, Akhmetzyanova, Ilseyar, Gao, Jie, Witkowski, Matthew, Guillamot, Maria, Gutkin, Michael C., Zhang, Yutong, Marier, Christian, Diefenbach, Catherine, Kousteni, Stavroula, Heguy, Adriana, Zhong, Hua, Fooksman, David R., Butler, Jason M., Economides, Aris, Frenette, Paul S., Adams, Ralf H., Satija, Rahul, Tsirigos, Aristotelis, Aifantis, Iannis

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RNA Interactions Are Essential for CTCF-Mediated Genome Organization von Saldaña-Meyer, Ricardo, Rodriguez-Hernaez, Javier, Escobar, Thelma, Nishana, Mayilaadumveettil, Jácome-López, Karina, Nora, Elphege P., Bruneau, Benoit G., Tsirigos, Aristotelis, Furlan-Magaril, Mayra, Skok, Jane, Reinberg, Danny

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Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment von Chen, Xufeng, Glytsou, Christina, Zhou, Hua, Narang, Sonali, Reyna, Denis E, Lopez, Andrea, Sakellaropoulos, Theodore, Gong, Yixiao, Kloetgen, Andreas, Yap, Yoon Sing, Wang, Eric, Gavathiotis, Evripidis, Tsirigos, Aristotelis, Tibes, Raoul, Aifantis, Iannis

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KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks von Di Giammartino, Dafne Campigli, Kloetgen, Andreas, Polyzos, Alexander, Liu, Yiyuan, Kim, Daleum, Murphy, Dylan, Abuhashem, Abderhman, Cavaliere, Paola, Aronson, Boaz, Shah, Veevek, Dephoure, Noah, Stadtfeld, Matthias, Tsirigos, Aristotelis, Apostolou, Effie

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Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries von Gong, Yixiao, Lazaris, Charalampos, Sakellaropoulos, Theodore, Lozano, Aurelie, Kambadur, Prabhanjan, Ntziachristos, Panagiotis, Aifantis, Iannis, Tsirigos, Aristotelis

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Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer von Lopez, Andrea, Reyna, Denis E., Gitego, Nadege, Kopp, Felix, Zhou, Hua, Miranda-Roman, Miguel A., Nordstrøm, Lars Ulrik, Narayanagari, Swathi-Rao, Chi, Ping, Vilar, Eduardo, Tsirigos, Aristotelis, Gavathiotis, Evripidis

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Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression von Cimmino, Luisa, Dolgalev, Igor, Wang, Yubao, Yoshimi, Akihide, Martin, Gaëlle H., Wang, Jingjing, Ng, Victor, Xia, Bo, Witkowski, Matthew T., Mitchell-Flack, Marisa, Grillo, Isabella, Bakogianni, Sofia, Ndiaye-Lobry, Delphine, Martín, Miguel Torres, Guillamot, Maria, Banh, Robert S., Xu, Mingjiang, Figueroa, Maria E., Dickins, Ross A., Abdel-Wahab, Omar, Park, Christopher Y., Tsirigos, Aristotelis, Neel, Benjamin G., Aifantis, Iannis

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Interleukin-17 governs hypoxic adaptation of injured epithelium von Konieczny, Piotr, Xing, Yue, Sidhu, Ikjot, Subudhi, Ipsita, Mansfield, Kody P, Hsieh, Brandon, Biancur, Douglas E, Larsen, Samantha B, Cammer, Michael, Li, Dongqing, Landén, Ning Xu, Loomis, Cynthia, Heguy, Adriana, Tikhonova, Anastasia N, Tsirigos, Aristotelis, Naik, Shruti

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Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology von Zhang, Nan, Mendieta-Esteban, Julen, Magli, Alessandro, Lilja, Karin C., Perlingeiro, Rita C. R., Marti-Renom, Marc A., Tsirigos, Aristotelis, Dynlacht, Brian David

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HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking von Lazaris, Charalampos, Kelly, Stephen, Ntziachristos, Panagiotis, Aifantis, Iannis, Tsirigos, Aristotelis

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An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion von Hatzioannou, Aikaterini, Banos, Aggelos, Sakelaropoulos, Theodore, Fedonidis, Constantinos, Vidali, Maria-Sophia, Köhne, Maren, Händler, Kristian, Boon, Louis, Henriques, Ana, Koliaraki, Vasiliki, Georgiadis, Panagiotis, Zoidakis, Jerome, Termentzi, Aikaterini, Beyer, Marc, Chavakis, Triantafyllos, Boumpas, Dimitrios, Tsirigos, Aristotelis, Verginis, Panayotis

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Dynamic changes in the human methylome during differentiation von Laurent, Louise, Wong, Eleanor, Li, Guoliang, Huynh, Tien, Tsirigos, Aristotelis, Ong, Chin Thing, Low, Hwee Meng, Kin Sung, Ken Wing, Rigoutsos, Isidore, Loring, Jeanne, Wei, Chia-Lin

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H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization von Pelham-Webb, Bobbie, Polyzos, Alexander, Wojenski, Luke, Kloetgen, Andreas, Li, Jiexi, Di Giammartino, Dafne Campigli, Sakellaropoulos, Theodore, Tsirigos, Aristotelis, Core, Leighton, Apostolou, Effie

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Bacteriophages as potential new mammalian pathogens von Tetz, George V., Ruggles, Kelly V., Zhou, Hua, Heguy, Adriana, Tsirigos, Aristotelis, Tetz, Victor

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CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters von Ortabozkoyun, Havva, Huang, Pin-Yao, Cho, Hyunwoo, Narendra, Varun, LeRoy, Gary, Gonzalez-Buendia, Edgar, Skok, Jane A., Tsirigos, Aristotelis, Mazzoni, Esteban O., Reinberg, Danny

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Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells von Kirkling, Margaret E., Cytlak, Urszula, Lau, Colleen M., Lewis, Kanako L., Resteu, Anastasia, Khodadadi-Jamayran, Alireza, Siebel, Christian W., Salmon, Hélène, Merad, Miriam, Tsirigos, Aristotelis, Collin, Matthew, Bigley, Venetia, Reizis, Boris

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Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease von Liu, Menghan, Devlin, Joseph C., Hu, Jiyuan, Volkova, Angelina, Battaglia, Thomas W., Ho, Melody, Asplin, John R., Byrd, Allyson, Loke, P'ng, Li, Huilin, Ruggles, Kelly, Tsirigos, Aristotelis, Blaser, Martin J., Nazzal, Lama

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