AKT signaling in normal and malignant cells von Testa, Joseph R, Tsichlis, Philip N

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Regulation of the Akt kinase by interacting proteins von Du, Keyong, Tsichlis, Philip N

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The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines von JULIEN GRILLE, Sylvia, BELLACOSA, Alfonso, UPSON, John, KLEIN-SZANTO, Andres J, VAN ROY, Frans, LEE-KWON, Whaseon, DONOWITZ, Mark, TSICHLIS, Philip N, LARUE, Lionel

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AKT/PKB AND OTHER D3 PHOSPHOINOSITIDE-REGULATED KINASES: Kinase Activation by Phosphoinositide-Dependent Phosphorylation von Chan, Tung O, Rittenhouse, Susan E, Tsichlis, Philip N

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In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis von Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye Malli, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Wu, Katherine, Oberli, Matthias A, Sánchez-Rivera, Francisco J, Park, Yoona K, Liang, Xu, Eng, George, Taylor, Martin S, Azimi, Roxana, Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Sicinska, Ewa T, Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam J, Tsichlis, Philip N, Lees, Jacqueline, Langer, Robert, Hynes, Richard O, Chen, Jianzhu, Bhutkar, Arjun, Jacks, Tyler, Yilmaz, Ömer H

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TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway von Dumitru, Calin D, Ceci, Jeffrey D, Tsatsanis, Christos, Kontoyiannis, Dimitris, Stamatakis, Konstantinos, Lin, Jun-Hsiang, Patriotis, Christos, Jenkins, Nancy A, Copeland, Neal G, Kollias, George, Tsichlis, Philip N

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Physical and functional interaction of the TPL2 kinase with nucleophosmin von Kanellis, D C, Bursac, S, Tsichlis, P N, Volarevic, S, Eliopoulos, A G

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Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals von Eliopoulos, Aristides G., Dumitru, Calin D., Wang, Chun-Chi, Cho, Jeonghee, Tsichlis, Philip N.

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AKT1/PKBα Kinase Is Frequently Elevated in Human Cancers and Its Constitutive Activation Is Required for Oncogenic Transformation in NIH3T3 Cells von Sun, Mei, Wang, Gen, Paciga, June E., Feldman, Richard I., Yuan, Zeng-Qiang, Ma, Xiao-Ling, Shelley, Sue A., Jove, Richard, Tsichlis, Philip N., Nicosia, Santo V., Cheng, Jin Q.

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Tpl2/Cot Signals Activate ERK, JNK, and NF-κB in a Cell-type and Stimulus-specific Manner von Das, Santasabuj, Cho, Jeonghee, Lambertz, Irina, Kelliher, Michelle A., Eliopoulos, Aristides G., Du, Keyong, Tsichlis, Philip N.

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Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40 von Eliopoulos, Aristides G, Tsichlis, Philip N, Wang, Chun-Chi, Dumitru, Calin D

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal von Kennedy, S G, Wagner, A J, Conzen, S D, Jordán, J, Bellacosa, A, Tsichlis, P N, Hay, N

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c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo von Shao, Zhili, Bhattacharya, Kausik, Hsich, Eileen, Park, Larry, Walters, Brian, Germann, Ursula, Wang, Yow-Ming, Kyriakis, John, Mohanlal, Ramon, Kuida, Keisuke, Namchuk, Mark, Salituro, Francesco, Yao, Yung-mae, Hou, Wei-min, Chen, Xin, Aronovitz, Mark, Tsichlis, Philip N, Bhattacharya, Susmita, Force, Thomas, Kilter, Heiko

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Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway von Muise-Helmericks, Robin C., Grimes, H. Leighton, Bellacosa, Alfonso, Malstrom, Scott E., Tsichlis, Philip N., Rosen, Neal

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Growth Factor Independent-1 Induced by IL-4 Regulates Th2 Cell Proliferation von Zhu, Jinfang, Guo, Liying, Min, Booki, Watson, Cynthia J, Hu-Li, Jane, Young, Howard A, Tsichlis, Philip N, Paul, William E

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Transduction of Interleukin-2 Antiapoptotic and Proliferative Signals via Akt Protein Kinase von Ahmed, Naheed N., Grimes, H. Leighton, Bellacosa, Alfonso, Chan, Tung O., Tsichlis, Philip N.

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Phosphorylation at Thr-290 Regulates Tpl2 Binding to NF-κB1/p105 and Tpl2 Activation and Degradation by Lipopolysaccharide von Cho, Jeonghee, Tsichlis, Philip N., Coffin, John M.

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A Novel Plant Glutathione S-Transferase/Peroxidase Suppresses Bax Lethality in Yeast von Kampranis, Sotirios C., Damianova, Radostina, Atallah, Mirna, Toby, Garabet, Kondi, Greta, Tsichlis, Philip N., Makris, Antonios M.

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Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit von Chan, Tung O., Rodeck, Ulrich, Chan, Andrew M., Kimmelman, Alec C., Rittenhouse, Susan E., Panayotou, George, Tsichlis, Philip N.

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Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway von Skorski, Tomasz, Bellacosa, Alfonso, Nieborowska-Skorska, Margaret, Majewski, Miroslaw, Martinez, Robert, Choi, John K., Trotta, Rossana, Wlodarski, Pawel, Perrotti, Danilo, Chan, Tung O., Wasik, Mariusz A., Tsichlis, Philip N., Calabretta, Bruno

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