Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling von Brady, Lauren, Kriner, Michelle, Coleman, Ilsa, Morrissey, Colm, Roudier, Martine, True, Lawrence D., Gulati, Roman, Plymate, Stephen R., Zhou, Zoey, Birditt, Brian, Meredith, Rhonda, Geiss, Gary, Hoang, Margaret, Beechem, Joseph, Nelson, Peter S.

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Androgen receptor variants occur frequently in castration resistant prostate cancer metastases von Zhang, Xiaotun, Morrissey, Colm, Sun, Shihua, Ketchandji, Melanie, Nelson, Peter S, True, Lawrence D, Vakar-Lopez, Funda, Vessella, Robert L, Plymate, Stephen R

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ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors von Nguyen, Liem T., Tretiakova, Maria S., Silvis, Mark R., Lucas, Jared, Klezovitch, Olga, Coleman, Ilsa, Bolouri, Hamid, Kutyavin, Vassily I., Morrissey, Colm, True, Lawrence D., Nelson, Peter S., Vasioukhin, Valeri

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LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease an­­d Serve as Models for Evaluating Cancer Therapeutics von Nguyen, Holly M., Vessella, Robert L., Morrissey, Colm, Brown, Lisha G., Coleman, Ilsa M., Higano, Celestia S., Mostaghel, Elahe A., Zhang, Xiaotun, True, Lawrence D., Lam, Hung‐Ming, Roudier, Martine, Lange, Paul H., Nelson, Peter S., Corey, Eva

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Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues von Glaser, Adam K., Reder, Nicholas P., Chen, Ye, Yin, Chengbo, Wei, Linpeng, Kang, Soyoung, Barner, Lindsey A., Xie, Weisi, McCarty, Erin F., Mao, Chenyi, Halpern, Aaron R., Stoltzfus, Caleb R., Daniels, Jonathan S., Gerner, Michael Y., Nicovich, Philip R., Vaughan, Joshua C., True, Lawrence D., Liu, Jonathan T. C.

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Genomic and phenotypic heterogeneity in prostate cancer von Haffner, Michael C., Zwart, Wilbert, Roudier, Martine P., True, Lawrence D., Nelson, William G., Epstein, Jonathan I., De Marzo, Angelo M., Nelson, Peter S., Yegnasubramanian, Srinivasan

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Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer von Sharp, Adam, Coleman, Ilsa, Yuan, Wei, Sprenger, Cynthia, Dolling, David, Rodrigues, Daniel Nava, Russo, Joshua W, Figueiredo, Ines, Bertan, Claudia, Seed, George, Riisnaes, Ruth, Uo, Takuma, Neeb, Antje, Welti, Jonathan, Morrissey, Colm, Carreira, Suzanne, Luo, Jun, Nelson, Peter S, Balk, Steven P, True, Lawrence D, de Bono, Johann S, Plymate, Stephen R

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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis von Lucas, Jared M, Heinlein, Cynthia, Kim, Tom, Hernandez, Susana A, Malik, Muzdah S, True, Lawrence D, Morrissey, Colm, Corey, Eva, Montgomery, Bruce, Mostaghel, Elahe, Clegg, Nigel, Coleman, Ilsa, Brown, Christopher M, Schneider, Eric L, Craik, Charles, Simon, Julian A, Bedalov, Antonio, Nelson, Peter S

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Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer von Kumar, Akash, Coleman, Ilsa, Morrissey, Colm, Zhang, Xiaotun, True, Lawrence D, Gulati, Roman, Etzioni, Ruth, Bolouri, Hamid, Montgomery, Bruce, White, Thomas, Lucas, Jared M, Brown, Lisha G, Dumpit, Ruth F, DeSarkar, Navonil, Higano, Celestia, Yu, Evan Y, Coleman, Roger, Schultz, Nikolaus, Fang, Min, Lange, Paul H, Shendure, Jay, Vessella, Robert L, Nelson, Peter S

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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling von Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F., Kaipainen, Arja, Corella, Alexandra N., Yang, Yu Chi, Nyquist, Michael D., Mostaghel, Elahe, Hsieh, Andrew C., Zhang, Xiaotun, Corey, Eva, Brown, Lisha G., Nguyen, Holly M., Pienta, Kenneth, Ittmann, Michael, Schweizer, Michael, True, Lawrence D., Wise, David, Rennie, Paul S., Vessella, Robert L., Morrissey, Colm, Nelson, Peter S.

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Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer von Labrecque, Mark P, Coleman, Ilsa M, Brown, Lisha G, True, Lawrence D, Kollath, Lori, Lakely, Bryce, Nguyen, Holly M, Yang, Yu C, da Costa, Rui M Gil, Kaipainen, Arja, Coleman, Roger, Higano, Celestia S, Yu, Evan Y, Cheng, Heather H, Mostaghel, Elahe A, Montgomery, Bruce, Schweizer, Michael T, Hsieh, Andrew C, Lin, Daniel W, Corey, Eva, Nelson, Peter S, Morrissey, Colm

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Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth von Montgomery, R Bruce, Mostaghel, Elahe A, Vessella, Robert, Hess, David L, Kalhorn, Thomas F, Higano, Celestia S, True, Lawrence D, Nelson, Peter S

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Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens von Glaser, Adam K., Reder, Nicholas P., Chen, Ye, McCarty, Erin F., Yin, Chengbo, Wei, Linpeng, Wang, Yu, True, Lawrence D., Liu, Jonathan T. C.

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How Accurately does PSMA Inhibitor 18F-DCFPyL-PET-CT Image Prostate Cancer? von True, Lawrence D., Chen, Delphine L.

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Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease von DI VIZIO, Dolores, KIM, Jayoung, DEMICHELIS, Francesca, FREEMAN, Michael R, HAGER, Martin H, MORELLO, Matteo, WEI YANGI, LAFARGUE, Christopher J, TRUE, Lawrence D, RUIN, Mark A, ADAM, Rosalyn M, BEROUKHIM, Rameen

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Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B von Sun, Yu, Campisi, Judith, Higano, Celestia, Beer, Tomasz M, Porter, Peggy, Coleman, Ilsa, True, Lawrence, Nelson, Peter S

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Aggressive Variants of Castration-Resistant Prostate Cancer von BELTRAN, Himisha, TOMLINS, Scott, LOGOTHETIS, Christopher, RUBIN, Mark A, APARICIO, Ana, ARORA, Vivek, RICKMAN, David, AYALA, Gustavo, HUANG, Jiaoti, TRUE, Lawrence, GLEAVE, Martin E, SOULE, Howard

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SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer von Zhang, Xiaotun, Coleman, Ilsa M, Brown, Lisha G, True, Lawrence D, Kollath, Lori, Lucas, Jared M, Lam, Hung-Ming, Dumpit, Ruth, Corey, Eva, Chéry, Lisly, Lakely, Bryce, Higano, Celestia S, Montgomery, Bruce, Roudier, Martine, Lange, Paul H, Nelson, Peter S, Vessella, Robert L, Morrissey, Colm

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Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer von Corella, Alexandra N., Ordonio, Ma Victoria Andrea Cabiliza, Coleman, Ilsa, Lucas, Jared M., Kaipainen, Arja, Nguyen, Holly M., Sondheim, Daniel, Brown, Lisha G., True, Lawrence D., Lee, John K., MacPherson, David, Nghiem, Paul, Gulati, Roman, Morrissey, Colm, Corey, Eva, Nelson, Peter S.

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Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy von Bhatia, Vipul, Kamat, Nikhil V., Pariva, Tiffany E., Wu, Li-Ting, Tsao, Annabelle, Sasaki, Koichi, Sun, Huiyun, Javier, Gerardo, Nutt, Sam, Coleman, Ilsa, Hitchcock, Lauren, Zhang, Ailin, Rudoy, Dmytro, Gulati, Roman, Patel, Radhika A., Roudier, Martine P., True, Lawrence D., Srivastava, Shivani, Morrissey, Colm M., Haffner, Michael C., Nelson, Peter S., Priceman, Saul J., Ishihara, Jun, Lee, John K.

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