Acoustic Ejection Mass Spectrometry for High-Throughput Analysis von Zhang, Hui, Liu, Chang, Hua, Wenyi, Ghislain, Lucien P, Liu, Jianhua, Aschenbrenner, Lisa, Noell, Stephen, Dirico, Kenneth J, Lanyon, Lorraine F, Steppan, Claire M, West, Mike, Arnold, Don W, Covey, Thomas R, Datwani, Sammy S, Troutman, Matthew D

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Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination von Varma, Manthena V. S, Obach, R. Scott, Rotter, Charles, Miller, Howard R, Chang, George, Steyn, Stefanus J, El-Kattan, Ayman, Troutman, Matthew D

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Defining Desirable Central Nervous System Drug Space through the Alignment of Molecular Properties, in Vitro ADME, and Safety Attributes von Wager, Travis T, Chandrasekaran, Ramalakshmi Y, Hou, Xinjun, Troutman, Matthew D, Verhoest, Patrick R, Villalobos, Anabella, Will, Yvonne

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High-Throughput Compound Quality Assessment with High-Mass-Resolution Acoustic Ejection Mass Spectrometry: An Automatic Data Processing Toolkit von Quinn, Alandra, Ivosev, Gordana, Chin, Jefferson, Mongillo, Robert, Veiga, Cristiano, Covey, Thomas R., Kapinos, Brendon, Khunte, Bhagyashree, Zhang, Hui, Troutman, Matthew D., Liu, Chang

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Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex von Ha, Sha, Li, Fengsheng, Troutman, Matthew C, Freed, Daniel C, Tang, Aimin, Loughney, John W, Wang, Dai, Wang, I-Ming, Vlasak, Josef, Nickle, David C, Rustandi, Richard R, Hamm, Melissa, DePhillips, Pete A, Zhang, Ningyan, McLellan, Jason S, Zhu, Hua, Adler, Stuart P, McVoy, Michael A, An, Zhiqiang, Fu, Tong-Ming

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A Comparison of Two Stability Proteomics Methods for Drug Target Identification in OnePot 2D Format von Xu, Yingrong, West, Graham M, Abdelmessih, Mario, Troutman, Matthew D, Everley, Robert A

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The Effect of Breast Cancer Resistance Protein and P-Glycoprotein on the Brain Penetration of Flavopiridol, Imatinib Mesylate (Gleevec), Prazosin, and 2-Methoxy-3-(4-(2-(5-methyl-2... von Zhou, Lin, Schmidt, Kari, Nelson, Frederick R, Zelesky, Veronica, Troutman, Matthew D, Feng, Bo

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Fully automated high-throughput immuno-µPlaque assay for live-attenuated tetravalent dengue vaccine development von Wang, Yi, Troutman, Matthew C, Hofmann, Carl, Gonzalez, Ariel, Song, Liping, Levin, Robert, Pixley, Heidi Yoder, Kearns, Kristine, DePhillips, Pete, Loughney, John W

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Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design von Di, Li, Keefer, Christopher, Scott, Dennis O., Strelevitz, Timothy J., Chang, George, Bi, Yi-An, Lai, Yurong, Duckworth, Jonathon, Fenner, Katherine, Troutman, Matthew D., Obach, R. Scott

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Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes von Liu, Jianhua, Vernikovskaya, Daria, Bora, Gary, Carlo, Anthony, Burchett, Woodrow, Jordan, Samantha, Tang, Lloyd Wei Tat, Yang, Joy, Che, Ye, Chang, George, Troutman, Matthew D., Di, Li

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In Vitro-In Vivo Extrapolation of Key Transporter Activity at the Blood-Brain Barrier von Trapa, Patrick E, Troutman, Matthew D, Lau, Thomas Y, Wager, Travis T, Maurer, Tristan S, Patel, Nandini C, West, Mark A, Umland, John P, Carlo, Anthony A, Feng, Bo, Liras, Jennifer L

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Development of a new permeability assay using low‐efflux MDCKII cells von Di, Li, Whitney‐Pickett, Carrie, Umland, John P., Zhang, Hui, Zhang, Xun, Gebhard, David F., Lai, Yurong, Federico, James J., Davidson, Ralph E., Smith, Russ, Reyner, Eric L., Lee, Caroline, Feng, Bo, Rotter, Charles, Varma, Manthena V., Kempshall, Sarah, Fenner, Katherine, El‐kattan, Ayman F., Liston, Theodore E., Troutman, Matthew D.

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Physicochemical Determinants of Human Renal Clearance von Varma, Manthena V. S, Feng, Bo, Obach, R. Scott, Troutman, Matthew D, Chupka, Jonathan, Miller, Howard R, El-Kattan, Ayman

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Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry von DiRico, Kenneth J., Hua, Wenyi, Liu, Chang, Tucker, Joseph W., Ratnayake, Anokha S., Flanagan, Mark E., Troutman, Matthew D., Noe, Mark C., Zhang, Hui

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Species Independence in Brain Tissue Binding Using Brain Homogenates von LI DI, UMLAND, John P, CHANG, George, YOUPING HUANG, ZHEN LIN, SCOTT, Dennis O, TROUTMAN, Matthew D, LISTON, Theodore E

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Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium von TROUTMAN, Matthew D, THAKKER, Dhiren R

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Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex von Yazdi, Aliakbar Khalili, Perveen, Sumera, Dong, Cheng, Song, Xiaosheng, Dong, Aiping, Szewczyk, Magdalena M, Calabrese, Matthew F, Casimiro-Garcia, Agustin, Chakrapani, Subramanyam, Dowling, Matthew S, Ficici, Emel, Lee, Jisun, Montgomery, Justin I, O'Connell, Thomas N, Skrzypek, Grzegorz J, Tran, Tuan P, Troutman, Matthew D, Wang, Feng, Young, Jennifer A, Min, Jinrong, Barsyte-Lovejoy, Dalia, Brown, Peter J, Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H, Vedadi, Masoud, Owen, Dafydd R

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Soluble Human Cytomegalovirus gH/gL/pUL128–131 Pentameric Complex, but Not gH/gL, Inhibits Viral Entry to Epithelial Cells and Presents Dominant Native Neutralizing Epitopes von Loughney, John W., Rustandi, Richard R., Wang, Dai, Troutman, Matthew C., Dick, Lawrence W., Li, Guanghua, Liu, Zhong, Li, Fengsheng, Freed, Daniel C., Price, Colleen E., Hoang, Van M., Culp, Timothy D., DePhillips, Pete A., Fu, Tong-Ming, Ha, Sha

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Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: Asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell... von TROUTMAN, Matthew D, THAKKER, Dhiren R

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HIGH-RESOLUTION NEAR-INFRARED SPECTROSCOPY OF HD 100546. I. ANALYSIS OF ASYMMETRIC RO-VIBRATIONAL OH EMISSION LINES von Liskowsky, Joseph P, Brittain, Sean D, Najita, Joan R, Carr, John S, DOPPMANN, GREG W, Troutman, Matthew R

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