Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study von Varma, Vijay R, Oommen, Anup M, Varma, Sudhir, Casanova, Ramon, An, Yang, Andrews, Ryan M, O'Brien, Richard, Pletnikova, Olga, Troncoso, Juan C, Toledo, Jon, Baillie, Rebecca, Arnold, Matthias, Kastenmueller, Gabi, Nho, Kwangsik, Doraiswamy, P Murali, Saykin, Andrew J, Kaddurah-Daouk, Rima, Legido-Quigley, Cristina, Thambisetty, Madhav

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Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study von Mahajan, Uma V., Varma, Vijay R., Griswold, Michael E., Blackshear, Chad T., An, Yang, Oommen, Anup M., Varma, Sudhir, Troncoso, Juan C., Pletnikova, Olga, O'Brien, Richard, Hohman, Timothy J., Legido-Quigley, Cristina, Thambisetty, Madhav

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TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD von Ling, Jonathan P., Pletnikova, Olga, Troncoso, Juan C., Wong, Philip C.

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Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption von Froelicher, David, Troncoso-Pastoriza, Juan R., Raisaro, Jean Louis, Cuendet, Michel A., Sousa, Joao Sa, Cho, Hyunghoon, Berger, Bonnie, Fellay, Jacques, Hubaux, Jean-Pierre

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Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model von Lasagna-Reeves, Cristian A., de Haro, Maria, Hao, Shuang, Park, Jeehye, Rousseaux, Maxime W.C., Al-Ramahi, Ismael, Jafar-Nejad, Paymaan, Vilanova-Velez, Luis, See, Lauren, De Maio, Antonia, Nitschke, Larissa, Wu, Zhenyu, Troncoso, Juan C., Westbrook, Thomas F., Tang, Jianrong, Botas, Juan, Zoghbi, Huda Y.

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RAN Translation in Huntington Disease von Bañez-Coronel, Monica, Ayhan, Fatma, Tarabochia, Alex D, Zu, Tao, Perez, Barbara A, Tusi, Solaleh Khoramian, Pletnikova, Olga, Borchelt, David R, Ross, Christopher A, Margolis, Russell L, Yachnis, Anthony T, Troncoso, Juan C, Ranum, Laura P W

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RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia von Zu, Tao, Liu, Yuanjing, Bañez-Coronel, Monica, Reid, Tammy, Pletnikova, Olga, Lewis, Jada, Miller, Timothy M, Harms, Matthew B, Falchook, Annet E, Subramony, S H, Ostrow, Lyle W, Rothstein, Jeffrey D, Troncoso, Juan C, Ranum, Laura P W

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Mutant Huntingtin Disrupts the Nuclear Pore Complex von Grima, Jonathan C., Daigle, J. Gavin, Arbez, Nicolas, Cunningham, Kathleen C., Zhang, Ke, Ochaba, Joseph, Geater, Charlene, Morozko, Eva, Stocksdale, Jennifer, Glatzer, Jenna C., Pham, Jacqueline T., Ahmed, Ishrat, Peng, Qi, Wadhwa, Harsh, Pletnikova, Olga, Troncoso, Juan C., Duan, Wenzhen, Snyder, Solomon H., Ranum, Laura P.W., Thompson, Leslie M., Lloyd, Thomas E., Ross, Christopher A., Rothstein, Jeffrey D.

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Arc/Arg3.1 Regulates an Endosomal Pathway Essential for Activity-Dependent β-Amyloid Generation von Wu, Jing, Petralia, Ronald S., Kurushima, Hideaki, Patel, Hiral, Jung, Mi-young, Volk, Lenora, Chowdhury, Shoaib, Shepherd, Jason D., Dehoff, Marlin, Li, Yueming, Kuhl, Dietmar, Huganir, Richard L., Price, Donald L., Scannevin, Robert, Troncoso, Juan C., Wong, Philip C., Worley, Paul F.

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Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo von Colla, Emanuela, Coune, Philippe, Liu, Ying, Pletnikova, Olga, Troncoso, Juan C, Iwatsubo, Takeshi, Schneider, Bernard L, Lee, Michael K

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C9orf72 nucleotide repeat structures initiate molecular cascades of disease von Haeusler, Aaron R., Donnelly, Christopher J., Periz, Goran, Simko, Eric A. J., Shaw, Patrick G., Kim, Min-Sik, Maragakis, Nicholas J., Troncoso, Juan C., Pandey, Akhilesh, Sattler, Rita, Rothstein, Jeffrey D., Wang, Jiou

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PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R) von Horti, Andrew G., Naik, Ravi, Foss, Catherine A., Minn, Il, Misheneva, Varia, Du, Yong, Wang, Yuchuan, Mathews, William B., Wu, Yunkou, Hall, Andrew, LaCourse, Catherine, Ahn, Hye-Hyun, Nam, Hwanhee, Lesniak, Wojciech G., Valentine, Heather, Pletnikova, Olga, Troncoso, Juan C., Smith, Matthew D., Calabresi, Peter A., Savonenko, Alena V., Dannals, Robert F., Pletnikov, Mikhail V., Pomper, Martin G.

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Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease von Johnson, Erik C B, Dammer, Eric B, Duong, Duc M, Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C, Lah, James J, Levey, Allan I, Seyfried, Nicholas T

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Amyloid‐beta is present in human lymph nodes and greatly enriched in those of the cervical region von Nauen, David W., Troncoso, Juan C.

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Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo von Colla, Emanuela, Jensen, Poul H, Pletnikova, Olga, Troncoso, Juan C, Glabe, Charles, Lee, Michael K

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Probing region-specific microstructure of human cortical areas using high angular and spatial resolution diffusion MRI von Aggarwal, Manisha, Nauen, David W., Troncoso, Juan C., Mori, Susumu

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Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease von Kam, Tae-In, Mao, Xiaobo, Park, Hyejin, Chou, Shih-Ching, Karuppagounder, Senthilkumar S, Umanah, George Essien, Yun, Seung Pil, Brahmachari, Saurav, Panicker, Nikhil, Chen, Rong, Andrabi, Shaida A, Qi, Chen, Poirier, Guy G, Pletnikova, Olga, Troncoso, Juan C, Bekris, Lynn M, Leverenz, James B, Pantelyat, Alexander, Ko, Han Seok, Rosenthal, Liana S, Dawson, Ted M, Dawson, Valina L

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Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation von Johnson, Erik C. B., Dammer, Eric B., Duong, Duc M., Ping, Lingyan, Zhou, Maotian, Yin, Luming, Higginbotham, Lenora A., Guajardo, Andrew, White, Bartholomew, Troncoso, Juan C., Thambisetty, Madhav, Montine, Thomas J., Lee, Edward B., Trojanowski, John Q., Beach, Thomas G., Reiman, Eric M., Haroutunian, Vahram, Wang, Minghui, Schadt, Eric, Zhang, Bin, Dickson, Dennis W., Ertekin-Taner, Nilüfer, Golde, Todd E., Petyuk, Vladislav A., De Jager, Philip L., Bennett, David A., Wingo, Thomas S., Rangaraju, Srikant, Hajjar, Ihab, Shulman, Joshua M., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

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Revolutionizing Medical Data Sharing Using Advanced Privacy-Enhancing Technologies: Technical, Legal, and Ethical Synthesis von Scheibner, James, Raisaro, Jean Louis, Troncoso-Pastoriza, Juan Ramon, Ienca, Marcello, Fellay, Jacques, Vayena, Effy, Hubaux, Jean-Pierre

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Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes von Kim, Dong Won, Tu, Kevin J, Wei, Alice, Lau, Ashley J, Gonzalez-Gil, Anabel, Cao, Tianyu, Braunstein, Kerstin, Ling, Jonathan P, Troncoso, Juan C, Wong, Philip C, Blackshaw, Seth, Schnaar, Ronald L, Li, Tong

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