Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study von Varma, Vijay R, Oommen, Anup M, Varma, Sudhir, Casanova, Ramon, An, Yang, Andrews, Ryan M, O'Brien, Richard, Pletnikova, Olga, Troncoso, Juan C, Toledo, Jon, Baillie, Rebecca, Arnold, Matthias, Kastenmueller, Gabi, Nho, Kwangsik, Doraiswamy, P Murali, Saykin, Andrew J, Kaddurah-Daouk, Rima, Legido-Quigley, Cristina, Thambisetty, Madhav

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TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD von Ling, Jonathan P., Pletnikova, Olga, Troncoso, Juan C., Wong, Philip C.

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Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study von Mahajan, Uma V, Varma, Vijay R, Griswold, Michael E, Blackshear, Chad T, An, Yang, Oommen, Anup M, Varma, Sudhir, Troncoso, Juan C, Pletnikova, Olga, O'Brien, Richard, Hohman, Timothy J, Legido-Quigley, Cristina, Thambisetty, Madhav

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Mutant Huntingtin Disrupts the Nuclear Pore Complex von Grima, Jonathan C., Daigle, J. Gavin, Arbez, Nicolas, Cunningham, Kathleen C., Zhang, Ke, Ochaba, Joseph, Geater, Charlene, Morozko, Eva, Stocksdale, Jennifer, Glatzer, Jenna C., Pham, Jacqueline T., Ahmed, Ishrat, Peng, Qi, Wadhwa, Harsh, Pletnikova, Olga, Troncoso, Juan C., Duan, Wenzhen, Snyder, Solomon H., Ranum, Laura P.W., Thompson, Leslie M., Lloyd, Thomas E., Ross, Christopher A., Rothstein, Jeffrey D.

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RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia von Zu, Tao, Liu, Yuanjing, Bañez-Coronel, Monica, Reid, Tammy, Pletnikova, Olga, Lewis, Jada, Miller, Timothy M, Harms, Matthew B, Falchook, Annet E, Subramony, S H, Ostrow, Lyle W, Rothstein, Jeffrey D, Troncoso, Juan C, Ranum, Laura P W

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Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model von Lasagna-Reeves, Cristian A., de Haro, Maria, Hao, Shuang, Park, Jeehye, Rousseaux, Maxime W.C., Al-Ramahi, Ismael, Jafar-Nejad, Paymaan, Vilanova-Velez, Luis, See, Lauren, De Maio, Antonia, Nitschke, Larissa, Wu, Zhenyu, Troncoso, Juan C., Westbrook, Thomas F., Tang, Jianrong, Botas, Juan, Zoghbi, Huda Y.

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Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease von Johnson, Erik C B, Dammer, Eric B, Duong, Duc M, Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C, Lah, James J, Levey, Allan I, Seyfried, Nicholas T

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Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway von Varma, V R, Varma, S, An, Y, Hohman, T J, Seddighi, S, Casanova, R, Beri, A, Dammer, E B, Seyfried, N T, Pletnikova, O, Moghekar, A, Wilson, M R, Lah, J J, O'Brien, R J, Levey, A I, Troncoso, J C, Albert, M S, Thambisetty, M

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The Nun Study: Clinically silent AD, neuronal hypertrophy, and linguistic skills in early life von IACONO, D, MARKESBERY, W. R, GROSS, M, PLETNIKOVA, O, RUDOW, G, ZANDI, P, TRONCOSO, J. C

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RAN Translation in Huntington Disease von Bañez-Coronel, Monica, Ayhan, Fatma, Tarabochia, Alex D, Zu, Tao, Perez, Barbara A, Tusi, Solaleh Khoramian, Pletnikova, Olga, Borchelt, David R, Ross, Christopher A, Margolis, Russell L, Yachnis, Anthony T, Troncoso, Juan C, Ranum, Laura P W

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PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R) von Horti, Andrew G., Naik, Ravi, Foss, Catherine A., Minn, Il, Misheneva, Varia, Du, Yong, Wang, Yuchuan, Mathews, William B., Wu, Yunkou, Hall, Andrew, LaCourse, Catherine, Ahn, Hye-Hyun, Nam, Hwanhee, Lesniak, Wojciech G., Valentine, Heather, Pletnikova, Olga, Troncoso, Juan C., Smith, Matthew D., Calabresi, Peter A., Savonenko, Alena V., Dannals, Robert F., Pletnikov, Mikhail V., Pomper, Martin G.

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Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes von Kim, Dong Won, Tu, Kevin J, Wei, Alice, Lau, Ashley J, Gonzalez-Gil, Anabel, Cao, Tianyu, Braunstein, Kerstin, Ling, Jonathan P, Troncoso, Juan C, Wong, Philip C, Blackshaw, Seth, Schnaar, Ronald L, Li, Tong

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Involvement of Oxidative Stress-Induced Abnormalities in Ceramide and Cholesterol Metabolism in Brain Aging and Alzheimer's Disease von Cutler, Roy G., Kelly, Jeremiah, Storie, Kristin, Pedersen, Ward A., Tammara, Anita, Hatanpaa, Kimmo, Troncoso, Juan C., Mattson, Mark P., Brady, Roscoe O.

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Probing region-specific microstructure of human cortical areas using high angular and spatial resolution diffusion MRI von Aggarwal, Manisha, Nauen, David W., Troncoso, Juan C., Mori, Susumu

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Arc/Arg3.1 Regulates an Endosomal Pathway Essential for Activity-Dependent β-Amyloid Generation von Wu, Jing, Petralia, Ronald S., Kurushima, Hideaki, Patel, Hiral, Jung, Mi-young, Volk, Lenora, Chowdhury, Shoaib, Shepherd, Jason D., Dehoff, Marlin, Li, Yueming, Kuhl, Dietmar, Huganir, Richard L., Price, Donald L., Scannevin, Robert, Troncoso, Juan C., Wong, Philip C., Worley, Paul F.

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Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation von Chuang, Y-F, An, Y, Bilgel, M, Wong, D F, Troncoso, J C, O'Brien, R J, Breitner, J C, Ferrucci, L, Resnick, S M, Thambisetty, M

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Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study von Varma, Vijay R, Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Delgado, João C, Oommen, Anup M, Roberts, Jackson A, Wong, Dean F, Davatzikos, Christos, Resnick, Susan M, Troncoso, Juan C, Pletnikova, Olga, O'Brien, Richard, Hak, Eelko, Baak, Brenda N, Pfeiffer, Ruth, Baloni, Priyanka, Mohmoudiandehkordi, Siamak, Nho, Kwangsik, Kaddurah-Daouk, Rima, Bennett, David A, Gadalla, Shahinaz M, Thambisetty, Madhav

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Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini von Na, Chan Hyun, Barbhuiya, Mustafa A, Kim, Min-Sik, Verbruggen, Steven, Eacker, Stephen M, Pletnikova, Olga, Troncoso, Juan C, Halushka, Marc K, Menschaert, Gerben, Overall, Christopher M, Pandey, Akhilesh

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A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease von Seyfried, Nicholas T., Dammer, Eric B., Swarup, Vivek, Nandakumar, Divya, Duong, Duc M., Yin, Luming, Deng, Qiudong, Nguyen, Tram, Hales, Chadwick M., Wingo, Thomas, Glass, Jonathan, Gearing, Marla, Thambisetty, Madhav, Troncoso, Juan C., Geschwind, Daniel H., Lah, James J., Levey, Allan I.

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MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein von Cho, Hyun Jin, Liu, Guoxiang, Jin, Seok Min, Parisiadou, Loukia, Xie, Chengsong, Yu, Jia, Sun, Lixin, Ma, Bo, Ding, Jinhui, Vancraenenbroeck, Renée, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, He, Ping, Troncoso, Juan C, Shen, Yong, Cai, Huaibin

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