Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors von Centanni, Maddalena, Moes, Dirk Jan A. R., Trocóniz, Iñaki F., Ciccolini, Joseph, van Hasselt, J. G. Coen

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Beyond Deterministic Models in Drug Discovery and Development von Irurzun-Arana, Itziar, Rackauckas, Christopher, McDonald, Thomas O., Trocóniz, Iñaki F.

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Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance von Irurzun-Arana, Itziar, McDonald, Thomas O., Troconiz, Inaki F., Michor, Franziska

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Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment von Sancho-Araiz, Aymara, Parra-Guillen, Zinnia P, Bragard, Jean, Ardanza, Sergio, Mangas-Sanjuan, Victor, Trocóniz, Iñaki F

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Population-Pharmacokinetic and Covariate Analysis of Lurbinectedin (PM01183), a New RNA Polymerase II Inhibitor, in Pooled Phase I/II Trials in Patients with Cancer von Fernandez-Teruel, Carlos, Gonzalez, Ignacio, Trocóniz, Iñaki F., Lubomirov, Rubin, Soto, Arturo, Fudio, Salvador

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Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia and the effect of L-carnitine supplementation von Schiavo, Alejandra, Maldonado, Cecilia, Vázquez, Marta, Fagiolino, Pietro, Trocóniz, Iñaki F., Ibarra, Manuel

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Optimal dynamic control approach in a multi-objective therapeutic scenario: Application to drug delivery in the treatment of prostate cancer von Irurzun-Arana, Itziar, Janda, Alvaro, Ardanza-Trevijano, Sergio, Trocóniz, Iñaki F

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A systems pharmacology model for inflammatory bowel disease von Balbas-Martinez, Violeta, Ruiz-Cerdá, Leire, Irurzun-Arana, Itziar, González-García, Ignacio, Vermeulen, An, Gómez-Mantilla, José David, Trocóniz, Iñaki F

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Advanced Boolean modeling of biological networks applied to systems pharmacology von Irurzun-Arana, Itziar, Pastor, José Martín, Trocóniz, Iñaki F, Gómez-Mantilla, José David

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Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tumor Heterogeneity to Overall Survival von Vera-Yunca, Diego, Girard, Pascal, Parra-Guillen, Zinnia P., Munafo, Alain, Trocóniz, Iñaki F., Terranova, Nadia

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Relevance of primary lesion location, tumour heterogeneity and genetic mutation demonstrated through tumour growth inhibition and overall survival modelling in metastatic colorecta... von Vera‐Yunca, Diego, Parra‐Guillen, Zinnia P., Girard, Pascal, Trocóniz, Iñaki F., Terranova, Nadia

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The Role of Mathematical Models in Immuno-Oncology: Challenges and Future Perspectives von Sancho-Araiz, Aymara, Mangas-Sanjuan, Victor, Troconiz, Inaki F.

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Foxp3 inhibitory peptide encapsulated in a novel CD25-targeted nanoliposome promotes efficient tumor regression in mice von Serrano, Alejandro, Casares, Noelia, Trocóniz, Iñaki F, Lozano, Teresa, Lasarte, Juan J, Zalba, Sara, Garrido, María J

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The Long Neglected Player: Modeling Tumor Uptake to Guide Optimal Dosing von Ruiz-Cerdá, Leire, Asín-Prieto, Eduardo, Parra-Guillen, Zinnia P, Trocóniz, Iñaki F

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Physiologically-Based Pharmacokinetic model for Ciprofloxacin in children with complicated Urinary Tract Infection von Balbas-Martinez, Violeta, Michelet, Robin, Edginton, Andrea N., Meesters, Kevin, Trocóniz, Iñaki F., Vermeulen, An

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Drug Exposure to Establish Pharmacokinetic–Response Relationships in Oncology von Solans, Belén P., Garrido, María Jesús, Trocóniz, Iñaki F.

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Untangling Absorption Mechanisms and Variability in Bioequivalence Studies Using Population Analysis von Ameijeiras Rodríguez, Carolina, Henriques, Sara Carolina, Sancho-Araiz, Aymara, Trocóniz, Iñaki F., Almeida, Luis, Silva, Nuno Elvas

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Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-β kinase antagonist, in mice von Bueno, Lorea, de Alwis, Dinesh P, Pitou, Celine, Yingling, Jonathan, Lahn, Michael, Glatt, Sophie, Trocóniz, Iñaki F

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Model-Based Meta-Analysis Supporting the Combination of Acetaminophen and Topical Diclofenac in Acute Pain: A Therapy for Mild-to-Moderate Osteoarthritis Pain? von Sethi, Vidhu, Qin, Li, Cox, Eugène, Trocóniz, Iñaki F., Della Pasqua, Oscar

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Tramadol and O-Desmethyl Tramadol Clearance Maturation and Disposition in Humans: A Pooled Pharmacokinetic Study von Allegaert, Karel, Holford, Nick, Anderson, Brian J., Holford, Sam, Stuber, Frank, Rochette, Alain, Trocóniz, Iñaki F., Beier, Horst, de Hoon, Jan N., Pedersen, Rasmus S., Stamer, Ulrike

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