Banking on metabolomics for novel therapies in TNBC von Tripp, Aurelien, Poulogiannis, George

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The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer von Najumudeen, Arafath K., Ceteci, Fatih, Fey, Sigrid K., Hamm, Gregory, Steven, Rory T., Hall, Holly, Nikula, Chelsea J., Dexter, Alex, Murta, Teresa, Race, Alan M., Sumpton, David, Vlahov, Nikola, Gay, David M., Knight, John R. P., Jackstadt, Rene, Leach, Joshua D. G., Ridgway, Rachel A., Johnson, Emma R., Nixon, Colin, Hedley, Ann, Gilroy, Kathryn, Clark, William, Malla, Sudhir B., Dunne, Philip D., Rodriguez-Blanco, Giovanny, Critchlow, Susan E., Mrowinska, Agata, Malviya, Gaurav, Solovyev, Dmitry, Brown, Gavin, Lewis, David Y., Mackay, Gillian M., Strathdee, Douglas, Tardito, Saverio, Gottlieb, Eyal, Takats, Zoltan, Barry, Simon T., Goodwin, Richard J. A., Bunch, Josephine, Bushell, Martin, Campbell, Andrew D., Sansom, Owen J.

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Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3 -Mutated Gliomas Recreate the Patient Tumor Complexity von Blandin, Anne-Florence, Durand, Aurélie, Litzler, Marie, Tripp, Aurélien, Guérin, Éric, Ruhland, Elisa, Obrecht, Adeline, Keime, Céline, Fuchs, Quentin, Reita, Damien, Lhermitte, Benoit, Coca, Andres, Jones, Chris, Rebel, Isabelle Lelong, Villa, Pascal, Namer, Izzie Jacques, Dontenwill, Monique, Guenot, Dominique, Entz-Werle, Natacha

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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids von Koundouros, Nikos, Karali, Evdoxia, Tripp, Aurelien, Valle, Adamo, Inglese, Paolo, Perry, Nicholas J.S., Magee, David J., Anjomani Virmouni, Sara, Elder, George A., Tyson, Adam L., Dória, Maria Luisa, van Weverwijk, Antoinette, Soares, Renata F., Isacke, Clare M., Nicholson, Jeremy K., Glen, Robert C., Takats, Zoltan, Poulogiannis, George

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Abstract PO-042: A multimodal analysis in breast cancer: Revealing metabolic heterogeneity using DESI-MS imaging with Laser-microdissection coupled transcriptome approach von Kazanc, Emine, Karali, Evi, Wu, Vincen, Inglese, Paolo, McKenzie, James, Tripp, Aurelien, Koundouros, Nikos, Tsalikis, Thanasis, Kudo, Hiromi, Poulogiannis, George, Takats, Zoltan

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Abstract A34: Hypoxia signaling pathway is frequently involved in pediatric osteosarcoma microenvironment, as diagnostic and prognostic biomarkers, but also as new therapeutic targ... von Pierrevelcin, Marina, Grain, Audrey, Tripp, Aurelien, Obrecht, Adeline, Lhermitte, Benoit, Weingertner, Noelle, Gaspar, Nathalie, Villa, Pascal, Lelong-Rebel, Isabelle, Redini, Françoise, Dontenwill, Monique, Entz-Werlé, Natacha

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A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis von Leslie, Theresa K., Tripp, Aurelien, James, Andrew D., Fraser, Scott P., Nelson, Michaela, Sajjaboontawee, Nattanan, Capatina, Alina L., Toss, Michael, Fadhil, Wakkas, Salvage, Samantha C., Garcia, Mar Arias, Beykou, Melina, Rakha, Emad, Speirs, Valerie, Bakal, Chris, Poulogiannis, George, Djamgoz, Mustafa B. A., Jackson, Antony P., Matthews, Hugh R., Huang, Christopher L-H, Holding, Andrew N., Chawla, Sangeeta, Brackenbury, William J.

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A three-gene signature to predict survival in pediatric osteosarcoma (OS) to follow patients toward liquid biopsy: A collaborative work in OS2006 protocol von Entz-Werle, Natacha, Tripp, Aurelien, Weingertner, Noëlle, Redini, Francoise, Brouchet, Anne, Gaspar, Nathalie, Brugieres, Laurence, Neumann, Sophie Piperno, Marec-Berard, Perrine, Dontenwill, Monique

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A novel Na v 1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis von Leslie, Theresa K, Tripp, Aurelien, James, Andrew D, Fraser, Scott P, Nelson, Michaela, Sajjaboontawee, Nattanan, Capatina, Alina L, Toss, Michael, Fadhil, Wakkas, Salvage, Samantha C, Garcia, Mar Arias, Beykou, Melina, Rakha, Emad, Speirs, Valerie, Bakal, Chris, Poulogiannis, George, Djamgoz, Mustafa B A, Jackson, Antony P, Matthews, Hugh R, Huang, Christopher L-H, Holding, Andrew N, Chawla, Sangeeta, Brackenbury, William J

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TMOD-06. PRIMARY CELL LINES OF PEDIATRIC HIGH GRADE GLIOMAS (PHGGS) WITH HISTONE H3.3 MUTATIONS ARE MIMICKING INTER AND INTRA-TUMOR HETEROGENEITY von Blandin, Anne-Florence, Durand, Aurélie, Litzler, Marie, Guerin, Eric, Tripp, Aurelien, Lelong-Rebel, Isabelle, Dontenwill, Monique, Namer, Izzie Jacques, Guenot, Dominique, Entz-Werle, Natacha

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A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis von Leslie, Theresa, Tripp, Aurelien, James, Andrew, Fraser, Scott P, Nelson, Michaela, Sajjaboontawee, Nattanan, Capatina, Alina, Toss, Michael, Fadhil, Wakkas, Salvage, Samantha, Arias Garcia, Mar, Beykou, Melina, Rakha, Emad, Speirs, Valerie, Bakal, Chris, Poulogiannis, George, Djamgoz, Mustafa B. A, Jackson, Antony P, Matthews, Hugh R, Huang, Christopher L-H, Chawla, Sangeeta, Holding, Andrew Nicholas, Brackenbury, Will

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A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis von Leslie, Theresa K, Tripp, Aurelien, James, Andrew D, Fraser, Scott P, Nelson, Michaela, Sajjaboontawee, Nattanan, Capatina, Alina L, Toss, Michael, Fadhil, Wakkas, Salvage, Samantha C, Garcia, Mar Arias, Beykou, Melina, Rakha, Emad, Speirs, Valerie, Bakal, Chris, Poulogiannis, George, Djamgoz, Mustafa BA, Jackson, Antony P, Matthews, Hugh R, Huang, Christopher L-H, Holding, Andrew N, Chawla, Sangeeta, Brackenbury, William J

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A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis von Leslie, Theresa K, Tripp, Aurelien, James, Andrew D, Fraser, Scott P, Nelson, Michaela, Sajjaboontawee, Nattanan, Capatina, Alina L, Toss, Michael, Fadhil, Wakkas, Salvage, Samantha C, Garcia, Mar Arias, Beykou, Melina, Rakha, Emad, Speirs, Valerie, Bakal, Chris, Poulogiannis, George, Djamgoz, Mustafa BA, Jackson, Antony P, Matthews, Hugh R, Huang, Christopher L-H, Holding, Andrew N, Chawla, Sangeeta, Brackenbury, William J

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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids von Koundouros, Nikos, Karali, Evdoxia, Tripp, Aurelien, Valle, Adamo, Inglese, Paolo, Perry, Nicholas JS, Magee, David J, Anjomani Virmouni, Sara, Elder, George A, Tyson, Adam L, Dória, Maria Luisa, van Weverwijk, Antoinette, Soares, Renata F, Isacke, Clare M, Nicholson, Jeremy K, Glen, Robert C, Takats, Zoltan, Poulogiannis, George

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