Senescent human hematopoietic progenitors show elevated expression of transposable elements and inflammatory genes von Capone, Stephen, Connor, Kwasi M., Colombo, Anthony, Li, Xin, Triche, Tim J., Ramsingh, Giridharan

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Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling von Grit, Jamie L, Johnson, Benjamin K, Dischinger, Patrick S, J Essenburg, Curt, Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A, Triche, Jr, Tim J, Graveel, Carrie R, Steensma, Matthew R

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Methylome of human senescent hematopoietic progenitors von Capone, Stephen, Colombo, Anthony R, Johnson, Benjamin K, Triche, Jr, Tim J, Ramsingh, Giridharan

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Abstract LB-227: Targeted next-generation sequencing (NGS) of circulating tumor cells (CTCs) and matched primary tumors von Liu, Stephen V., Dempsey, Paul W., Strauss, William, Xu, Yucheng, Xu, Tong, Winer-Jones, Jessamine, Triche, Tim J., Quinn, David I., McMurdie, Janine, Defusco, Andre, Goldkorn, Amir

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Additional file 6 of Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling von Grit, Jamie L., Johnson, Benjamin K., Dischinger, Patrick S., Essenburg, Curt J., Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A., Triche, Tim J., Graveel, Carrie R., Steensma, Matthew R.

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CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes von Unterman, Irene, Avrahami, Dana, Katsman, Efrat, Tim, Jr, Triche, Glaser, Benjamin, Berman, Benjamin P

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Validation of Myc-Associated Protein X (MAX) regulation in growth hormone secreting and nonfunctional pituitary adenoma von Tucker, Douglass W, Pangal, Dhiraj J, Du, Robin, Gogia, Angad S, Tafreshi, Ali, Ruzevick, Jacob, Hurth, Kyle T, Triche, Jr, Tim, Micko, Alexander, Carpten, John D, Shiroishi, Mark S, Carmichael, John D, Rhie, Suhn K, Zada, Gabriel

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Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia von Bertrums, Eline J M, Smith, Jenny L, Harmon, Lauren, Ries, Rhonda E, Wang, Yi-Cheng J, Alonzo, Todd A, Menssen, Andrew J, Chisholm, Karen M, Leonti, Amanda R, Tarlock, Katherine, Ostronoff, Fabiana, Pogosova-Agadjanyan, Era L, Kaspers, Gertjan J L, Hasle, Henrik, Dworzak, Michael, Walter, Christiane, Muhlegger, Nora, Morerio, Cristina, Pardo, Laura, Hirsch, Betsy, Raimondi, Susana, Cooper, Todd M, Aplenc, Richard, Gamis, Alan S, Kolb, Edward A, Farrar, Jason E, Stirewalt, Derek, Ma, Xiaotu, Shaw, Tim I, Furlan, Scott N, Brodersen, Lisa Eidenschink, Loken, Michael R, Van den Heuvel-Eibrink, Marry M, Zwaan, C Michel, Triche, Timothy J, Goemans, Bianca F, Meshinchi, Soheil

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Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans von Xicola, Rosa M, Manojlovic, Zarko, Augustus, Gaius J, Kupfer, Sonia S, Emmadi, Rajyasree, Alagiozian-Angelova, Victoria, Triche, Tim, Salhia, Bodour, Carpten, John, Llor, Xavier, Ellis, Nathan A

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Validation of Myc-Associated Protein X von Tucker, Douglass W, Pangal, Dhiraj J, Du, Robin, Gogia, Angad S, Tafreshi, Ali, Ruzevick, Jacob, Hurth, Kyle T, Triche, Tim, Micko, Alexander, Carpten, John D, Shiroishi, Mark S, Carmichael, John D, Rhie, Suhn K, Zada, Gabriel

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Patient-derived xenografts of central nervous system metastasis reveal expansion of aggressive minor clones von Tew, Ben Yi, Legendre, Christophe, Schroeder, Mark A, Triche, Tim, Gooden, Gerald C, Huang, Yizhou, Butry, Loren, Ma, Daniel J, Johnson, Kyle, Martinez, Rae Anne, Pierobon, Mariaelena, Petricoin, Emanuel F, O’shaughnessy, Joyce, Osborne, Cindy, Tapia, Coya, Buckley, David N, Glen, Jennifer, Bernstein, Mark, Sarkaria, Jann N, Toms, Steven A, Salhia, Bodour

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Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia von Abla, Oussama, Ries, Rhonda E., Triche, Tim, Gerbing, Robert B., Hirsch, Betsy, Raimondi, Susana, Cooper, Todd, Farrar, Jason E., Buteyn, Nathaniel, Harmon, Lauren M., Wen, Hong, Deshpande, Aniruddha J., Kolb, E. Anders, Gamis, Alan S., Aplenc, Richard, Alonzo, Todd, Meshinchi, Soheil

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Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup von Obermayer, Alyssa, Yao, Sijie, Smith, Jenny L., Ries, Rhonda E., Wang, Yi-Cheng, Farrar, Jason E, Furlan, Scott N, Triche, Tim, Ma, Xiaotu, Huang, Benjamin J., Wang, Xuefeng, Meshinchi, Soheil, Shaw, Timothy I.

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Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia von Huang, Benjamin J., Smith, Jenny L., Shaw, Timothy I., Furlan, Scott N, Ries, Rhonda E., Leonti, Amanda R., Crowgey, Erin Lynn, Wei, Lisa, Farrar, Jason E, Triche, Tim, Ma, Xiaotu, Le, Quy, Meshinchi, Soheil

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Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue von Shi, Jianxin, Marconett, Crystal N., Duan, Jubao, Hyland, Paula L., Li, Peng, Wang, Zhaoming, Wheeler, William, Zhou, Beiyun, Campan, Mihaela, Lee, Diane S., Huang, Jing, Zhou, Weiyin, Triche, Tim, Amundadottir, Laufey, Warner, Andrew, Hutchinson, Amy, Chen, Po-Han, Chung, Brian S. I., Pesatori, Angela C., Consonni, Dario, Bertazzi, Pier Alberto, Bergen, Andrew W., Freedman, Mathew, Siegmund, Kimberly D., Berman, Benjamin P., Borok, Zea, Chatterjee, Nilanjan, Tucker, Margaret A., Caporaso, Neil E., Chanock, Stephen J., Laird-Offringa, Ite A., Landi, Maria Teresa

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Abstract 991: Development and characterization of patient derived xenografts from central nervous system metastasis reveal minor clone expansion linked with aggressive tumor behavi... von Tew, Ben Yi, Legendre, Christophe, Triche, Tim, Gooden, Gerald C., Johnson, Kyle N., Martinez, Rae Anne, Petricoin, Emanuel F., Pierobon, Mariaelena, O'Shaughnessy, Joyce, Osborne, Cindy, Schroeder, Mark A., Ma, Daniel J., Bernstein, Mark, Sarkaria, Jann N., Toms, Steven A., Salhia, Bodour

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Independent phenotypic plasticity axes define distinct obesity sub-types von Yang, Chih-Hsiang, Fagnocchi, Luca, Apostle, Stefanos, Wegert, Vanessa, Casaní-Galdón, Salvador, Landgraf, Kathrin, Panzeri, Ilaria, Dror, Erez, Heyne, Steffen, Wörpel, Till, Chandler, Darrell P., Lu, Di, Yang, Tao, Gibbons, Elizabeth, Guerreiro, Rita, Bras, Jose, Thomasen, Martin, Grunnet, Louise G., Vaag, Allan A., Gillberg, Linn, Grundberg, Elin, Conesa, Ana, Körner, Antje, Pospisilik, J. Andrew

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Validation of Myc-Associated Protein X (MAX) regulation in growth hormone secreting and nonfunctional pituitary adenoma von Douglass W Tucker, Dhiraj J Pangal, Robin Du, Angad S Gogia, Ali Tafreshi, Jacob Ruzevick, Kyle T Hurth, Tim Triche, Alexander Micko, John D Carpten, Mark S Shiroishi, John D Carmichael, Suhn K Rhie, Gabriel Zada

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Mesothelin is a novel cell surface disease marker and potential therapeutic target in acute myeloid leukemia von Kaeding, Allison J., Barwe, Sonali P., Gopalakrishnapillai, Anilkumar, Ries, Rhonda E., Alonzo, Todd A., Gerbing, Robert B., Correnti, Colin, Loken, Michael R., Broderson, Lisa Eidenschink, Pardo, Laura, Le, Quy H., Tang, Thao, Leonti, Amanda R., Smith, Jenny L., Chou, Cassie K., Xu, Min, Triche, Tim, Kornblau, Steven M., Kolb, E. Anders, Tarlock, Katherine, Meshinchi, Soheil

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Abstract 287: Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue von Shi, Jianxin, Marconett, Crystal, Duan, Jubao, Hyland, Paula, Li, Peng, Wang, Zhaoming, Wheeler, William, Campan, Mihaela, Huang, Jing, Zhou, Weiyin, Triche, Tim, Amundadottir, Laufey, Hutchinson, Amy, Chen, Po-Han, Zhou, Beiyun, Chung, Brian, Bertazzi, Pier Alberto, Bergen, Andrew W., Freedman, Mathew, Lee, Diane, Siegmund, Kim, Warner, Andrew Clay, Berman, Ben, Pesatori, Angela C., Borok, Zea, Consonni, Dario, Chatterjee, Nilanjan, Tucker, Margaret, Caporaso, Neil, Chanock, Stephen J., Laird-Offringa, Ite A., Landi, Maria Teresa

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