Developing new metal-based therapeutics: challenges and opportunities von Hambley, Trevor W

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Chemistry. Metal-based therapeutics von Hambley, Trevor W

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Platinum Drug Distribution in Cancer Cells and Tumors von Klein, Alice V, Hambley, Trevor W

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Transporter and protease mediated delivery of platinum complexes for precision oncology von Hambley, Trevor W.

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A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake von Glenister, Alexandra, Simone, Michela I, Hambley, Trevor W

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Pt(iv) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate von Zhang, Jenny Z, Wexselblatt, Ezequiel, Hambley, Trevor W, Gibson, Dan

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Is Anticancer Drug Development Heading in the Right Direction? von HAMBLEY, Trevor W, HAIT, William N

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Facile Preparation of Mono-, Di- and Mixed-Carboxylato Platinum(IV) Complexes for Versatile Anticancer Prodrug Design von Zhang, Jenny Z., Bonnitcha, Paul, Wexselblatt, Ezequiel, Klein, Alice V., Najajreh, Yousef, Gibson, Dan, Hambley, Trevor W.

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Influence of Equatorial and Axial Carboxylato Ligands on the Kinetic Inertness of Platinum(IV) Complexes in the Presence of Ascorbate and Cysteine and within DLD‑1 Cancer Cells von Chen, Catherine K. J, Zhang, Jenny Z, Aitken, Jade B, Hambley, Trevor W

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Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin von Eljack, Nasma D, Ma, Ho-Yu M, Drucker, Janine, Shen, Clara, Hambley, Trevor W, New, Elizabeth J, Friedrich, Thomas, Clarke, Ronald J

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Harnessing the properties of cobalt coordination complexes for biological application von Renfrew, Anna K., O'Neill, Edward S., Hambley, Trevor W., New, Elizabeth J.

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Is ASCT2 a Suitable Vector for the Selective Delivery of Anticancer Drugs? Modification of Glutamine at Either the Carboxylate or the Side Chain Hinders Binding and Transport von M, Vinitha, Mohammed, Adnan Ibrahim, Briot, Chelsea, Ryan, Renae M, Hambley, Trevor W

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Water-Soluble α‑Amino Acid Complexes of Molybdenum as Potential Antidotes for Cyanide Poisoning: Synthesis and Catalytic Studies of Threonine, Methionine, Serine, and Leucine Compl... von Gretarsdottir, Johanna M, Jonsdottir, Sigridur, Lewis, William, Hambley, Trevor W, Suman, Sigridur G

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Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex von Yamamoto, Natsuho, Renfrew, Anna K, Kim, Byung J, Bryce, Nicole S, Hambley, Trevor W

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Studies of a Cobalt(III) Complex of the MMP Inhibitor Marimastat: A Potential Hypoxia-Activated Prodrug von Failes, Timothy W., Cullinane, Carleen, Diakos, Connie I., Yamamoto, Natsuho, Lyons, J. Guy, Hambley, Trevor W.

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trans-Platinum(iv) pro-drugs that exhibit unusual resistance to reduction by endogenous reductants and blood serum but are rapidly activated inside cells: 1 H NMR and XANES spectro... von Chen, Catherine K J, Kappen, Peter, Gibson, Dan, Hambley, Trevor W

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The impact of highly electron withdrawing carboxylato ligands on the stability and activity of platinum(IV) pro-drugs von Chen, Catherine K.J., Hambley, Trevor W.

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Bioreductive activation and drug chaperoning in cobalt pharmaceuticals von Hall, Matthew D, Failes, Timothy W, Yamamoto, Natsuho, Hambley, Trevor W

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Platinum binding preferences dominate the binding of novel polyamide amidine anthraquinone platinum() complexes to DNA von Lo, Anthony T. S, Chen, Jon K, Murray, Vincent, Todd, Matthew H, Hambley, Trevor W

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Interactions of cisplatin and the copper transporter CTR1 in human colon cancer cells von Akerfeldt, Mia C., Tran, Carmen M.-N., Shen, Clara, Hambley, Trevor W., New, Elizabeth J.

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