Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming von Simula, Luca, Pacella, Ilenia, Colamatteo, Alessandra, Procaccini, Claudio, Cancila, Valeria, Bordi, Matteo, Tregnago, Claudia, Corrado, Mauro, Pigazzi, Martina, Barnaba, Vincenzo, Tripodo, Claudio, Matarese, Giuseppe, Piconese, Silvia, Campello, Silvia

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Modulation of miR-210 alters phasing of circadian locomotor activity and impairs projections of PDF clock neurons in Drosophila melanogaster von Cusumano, Paola, Biscontin, Alberto, Sandrelli, Federica, Mazzotta, Gabriella M, Tregnago, Claudia, De Pittà, Cristiano, Costa, Rodolfo

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Novel Compounds Synergize With Venetoclax to Target KMT2A-Rearranged Pediatric Acute Myeloid Leukemia von Tregnago, Claudia, Benetton, Maddalena, Da Ros, Ambra, Borella, Giulia, Longo, Giorgia, Polato, Katia, Francescato, Samuela, Biffi, Alessandra, Pigazzi, Martina

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Knockdown of APOPT1/COA8 Causes Cytochrome c Oxidase Deficiency, Neuromuscular Impairment, and Reduced Resistance to Oxidative Stress in Drosophila melanogaster von Brischigliaro, Michele, Corrà, Samantha, Tregnago, Claudia, Fernandez-Vizarra, Erika, Zeviani, Massimo, Costa, Rodolfo, De Pittà, Cristiano

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MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation von Pigazzi, Martina, Manara, Elena, Bresolin, Silvia, Tregnago, Claudia, Beghin, Alessandra, Baron, Emma, Giarin, Emanuela, Cho, Er-Chieh, Masetti, Riccardo, Rao, Dinesh S, Sakamoto, Kathleen M, Basso, Giuseppe

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Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement von Pigazzi, Martina, Manara, Elena, Buldini, Barbara, Beqiri, Valzerda, Bisio, Valeria, Tregnago, Claudia, Rondelli, Roberto, Masetti, Riccardo, Putti, Maria Caterina, Fagioli, Franca, Rizzari, Carmelo, Pession, Andrea, Locatelli, Franco, Basso, Giuseppe

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P435: NOVEL COMPOUNDS TO TARGET KMT2A‐REARRANGED PEDIATRIC ACUTE MYELOID LEUKEMIA von Tregnago, Claudia, Benetton, Maddalena, Da Ros, Ambra, Borella, Giulia, Longo, Giorgia, Polato, Katia, Sabatino, Jolanda, DI Salvo, Giovanni, Locatelli, Franco, Pigazzi, Martina

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P414: PATIENT‐DERIVED XENOGRAFT MODELS ARE THE LEADING STRATEGY TO IDENTIFY NEW AGENTS FOR PEDIATRIC ACUTE MYELOID LEUKEMIA von Da Ros, Ambra, Indio, Valentina, Peloso, Alberto, Tregnago, Claudia, Borella, Giulia, Benetton, Maddalena, Longo, Giorgia, Bresolin, Silvia, Buldini, Barbara, Pession, Andrea, Locatelli, Franco, Pigazzi, Martina

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The long non-coding RNA CDK6-AS1 overexpression impacts on acute myeloid leukemia differentiation and mitochondrial dynamics von Porcù, Elena, Benetton, Maddalena, Bisio, Valeria, Da Ros, Ambra, Tregnago, Claudia, Borella, Giulia, Zanon, Carlo, Bordi, Matteo, Germano, Giuseppe, Manni, Sabrina, Campello, Silvia, Rao, Dinesh S., Locatelli, Franco, Pigazzi, Martina

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Molecular Measurable Residual Disease Assessment before Hematopoietic Stem Cell Transplantation in Pediatric Acute Myeloid Leukemia Patients: A Retrospective Study by the I-BFM Stu... von Benetton, Maddalena, Merli, Pietro, Walter, Christiane, Hansen, Maria, Da Ros, Ambra, Polato, Katia, Tregnago, Claudia, Abrahamsson, Jonas, Strocchio, Luisa, Sonneveld, Edwin, Fogelstrand, Linda, Von Neuhoff, Nils, Reinhardt, Dirk, Hasle, Henrik, Pigazzi, Martina, Locatelli, Franco

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Label-free, real-time on-chip sensing of living cells via grating-coupled surface plasmon resonance von Borile, Giulia, Rossi, Stefano, Filippi, Andrea, Gazzola, Enrico, Capaldo, Pietro, Tregnago, Claudia, Pigazzi, Martina, Romanato, Filippo

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Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia von Borella, Giulia, Da Ros, Ambra, Borile, Giulia, Porcù, Elena, Tregnago, Claudia, Benetton, Maddalena, Marchetti, Anna, Bisio, Valeria, Montini, Barbara, Michielotto, Barbara, Cani, Alice, Leszl, Anna, Campodoni, Elisabetta, Sandri, Monica, Montesi, Monica, Bresolin, Silvia, Cairo, Stefano, Buldini, Barbara, Locatelli, Franco, Pigazzi, Martina

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Bioelectric Reprogramming of the Bone Marrow Niche in Acute Myeloid Leukemia von Borella, Giulia, Benetton, Maddalena, Da Ros, Ambra, Longo, Giorgia, Borile, Giulia, Cani, Alice, Pigozzi, Diego Lopez, Bortolozzi, Mario, Bresolin, Silvia, Tregnago, Claudia, Locatelli, Franco, Pigazzi, Martina

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CD72 Is a Pan-Tumor Antigen Associated with Childhood Acute Leukemia von Buldini, Barbara, Faggin, Giovanni, Porcù, Elena, Scarparo, Pamela, Polato, Katia, Tregnago, Claudia, Varotto, Elena, Rizzardi, Paolo, Rizzari, Carmelo, Locatelli, Franco, Biffi, Alessandra, Pigazzi, Martina

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Mesenchymal Stromal Cell Secretome in Acute Myeloid Leukemia Bone Marrow Niche von Borella, Giulia, Longo, Giorgia, Da Ros, Ambra, Campodoni, Elisabetta, Montanari, Margherita, Benetton, Maddalena, Bertuccio, Salvatore Nicola, Sandri, Monica, Tregnago, Claudia, Masetti, Riccardo, Locatelli, Franco, Pigazzi, Martina

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Characterization of the Molecular Landscape of Pediatric Acute Myeloid Leukemia: A Retrospective AIEOP AML2013/01 Study von Benetton, Maddalena, Merli, Pietro, Santoro, Nicola, Lo Nigro, Luca, Tregnago, Claudia, Da Ros, Ambra, Polato, Katia, Zampieri, Veronica, Michielotto, Barbara, Francescato, Samuela, Leszl, Anna, Masetti, Riccardo, Buldini, Barbara, Biffi, Alessandra, Fagioli, Franca, Rizzari, Carmelo, Locatelli, Franco, Pigazzi, Martina

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Nucleophosmin (NPM1) Type D Genotype Is Associated with Distinct Outcome in Acute Myeloid Leukemia - an AIEOP-BFM and COG-SWOG Intergroup Collaboration von Pigazzi, Martina, Tregnago, Claudia, Ries, Rhonda E, Benetton, Maddalena, Alonzo, Todd A., Duployez, Nicolas, Sonneveld, Edwin, Abrahamsson, Jonas, Fogelstrand, Linda, Von Neuhoff, Nils, Hasle, Henrik, Reinhardt, Dirk, Locatelli, Franco, Meshinchi, Soheil

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Prognostic Role of Molecular MRD Variations during Treatment of Pediatric AML: A Retrospective AIEOP AML2013/01 Study von Pigazzi, Martina, Benetton, Maddalena, Merli, Pietro, Cuccurullo, Rosanna, Polato, Katia, Scarparo, Pamela, Tumino, Manuela, Cesaro, Simone, Mura, Rosa Maria, Micalizzi, Concetta, Tregnago, Claudia, Rizzari, Carmelo, Zecca, Marco, Buldini, Barbara, Locatelli, Franco

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DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML von Ries, Rhonda E, Ma, Xiaotu, Tregnago, Claudia, Alonzo, Todd A., Wang, Jim, Hylkema, Tiffany, Huang, Benjamin J, Torabi, Alireza, Peplinski, Jack H, Wallace, Logan K, Aplenc, Richard, Gamis, Alan S, Tarlock, Katherine, Locatelli, Franco, Pigazzi, Martina, Meshinchi, Soheil

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CD72 is a pan‐tumor antigen associated to pediatric acute leukemia von Buldini, Barbara, Faggin, Giovanni, Porcù, Elena, Scarparo, Pamela, Polato, Katia, Tregnago, Claudia, Varotto, Elena, Rizzardi, Paolo, Rizzari, Carmelo, Locatelli, Franco, Biffi, Alessandra, Pigazzi, Martina

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