The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing von Thuenauer, Roland, Landi, Alessia, Trefzer, Anne, Altmann, Silke, Wehrum, Sarah, Eierhoff, Thorsten, Diedrich, Britta, Dengjel, Joern, Nystroem, Alexander, Imberty, Anne, Roemer, Winfried

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Dynamic adoption of anergy by antigen-exhausted CD4+ T cells von Trefzer, Anne, Kadam, Pallavi, Wang, Shu-Hung, Pennavaria, Stefanie, Lober, Benedikt, Akçabozan, Batuhan, Kranich, Jan, Brocker, Thomas, Nakano, Naoko, Irmler, Martin, Beckers, Johannes, Straub, Tobias, Obst, Reinhard

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The Lectin LecB Induces Patches with Basolateral Characteristics at the Apical Membrane to Promote Pseudomonas aeruginosa Host Cell Invasion von Thuenauer, Roland, Kühn, Katja, Guo, Yubing, Kotsis, Fruzsina, Xu, Maokai, Trefzer, Anne, Altmann, Silke, Wehrum, Sarah, Heshmatpour, Najmeh, Faust, Brian, Landi, Alessia, Diedrich, Britta, Dengjel, Jörn, Kuehn, E Wolfgang, Imberty, Anne, Römer, Winfried

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Phosphatidylserine-positive extracellular vesicles boost effector CD8 + T cell responses during viral infection von Rausch, Lisa, Flaskamp, Lavinia, Ashokkumar, Ashretha, Trefzer, Anne, Ried, Christine, Buchholz, Veit R, Obst, Reinhard, Straub, Tobias, Brocker, Thomas, Kranich, Jan

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Antigen-exhausted CD4+ T cells deviate towards multiple states of anergy von Trefzer, Anne

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Dynamic Adoption of Anergy by Antigen-Exhausted CD4+ T Cells von Kadam, Pallavi, Trefzer, Anne, Wang, Shu-Hung, Pennavaria, Stefanie, Lober, Benedikt, Akcabozan, Batuhan, Kranich, Jan, Brocker, Thomas, Nakano, Naoko, Irmler, Martin, Beckers, Johannes, Straub, Tobias, Obst, Reinhard

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Dynamic Adoption of Anergy by Antigen-Exhausted CD4+ T Cells von Obst, Reinhard, Trefzer, Anne, Kadam, Pallavi, Wang, Shu-Hung, Pennavaria, Stefanie, Lober, Benedikt, Kranich, Jan, Brocker, Thomas, Irmler, Martin, Beckers, Johannes, Straub, Tobias

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TCR tuning and exhaustion of CD4+ T cells by persisting antigen von Obst, Reinhard, Trefzer, Anne, Pennavaria, Stefanie, Wang, Shu-Hung, Lober, Benedikt, Asoyan, Ayuna

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IMPROVED PROTEASE-ACTIVATABLE T CELL BISPECIFIC ANTIBODIES von GEIGER, Martina, TREFZER, Anne, KLEIN, Christian, UMAÑA, Pablo, BRUENKER, Peter

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Phase II Trial (BREAK-2) of the BRAF Inhibitor Dabrafenib (GSK2118436) in Patients With Metastatic Melanoma von ASCIERTO, Paolo A, MINOR, David, HAMID, Omid, AMARAVADI, Ravi, SIMEONE, Ester, WILHELM, Tabea, KIM, Kevin B, LONG, Georgina V, MARTIN, Anne-Marie, MAZUMDAR, Jolly, GOODMAN, Vicki L, TREFZER, Uwe, RIBAS, Antoni, LEBBE, Celeste, O'HAGAN, Anne, ARYA, Niki, GUCKERT, Mary, SCHADENDORF, Dirk, KEFFORD, Richard F, GROB, Jean-Jacques

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Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial von Long, Georgina V, Dr, Trefzer, Uwe, MD, Davies, Michael A, MD, Kefford, Richard F, Prof, Ascierto, Paolo A, MD, Chapman, Paul B, MD, Puzanov, Igor, MD, Hauschild, Axel, MD, Robert, Caroline, PhD, Algazi, Alain, MD, Mortier, Laurent, Prof, Tawbi, Hussein, PhD, Wilhelm, Tabea, MD, Zimmer, Lisa, MD, Switzky, Julie, MSN, Swann, Suzanne, PhD, Martin, Anne-Marie, PhD, Guckert, Mary, MSN, Goodman, Vicki, MD, Streit, Michael, MD, Kirkwood, John M, Prof, Schadendorf, Dirk, Prof

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Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma von Flaherty, Keith T, Robert, Caroline, Hersey, Peter, Nathan, Paul, Garbe, Claus, Milhem, Mohammed, Demidov, Lev V, Hassel, Jessica C, Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M.G, Utikal, Jochen, Dreno, Brigitte, Nyakas, Marta, Middleton, Mark R, Becker, Jürgen C, Casey, Michelle, Sherman, Laurie J, Wu, Frank S, Ouellet, Daniele, Martin, Anne-Marie, Patel, Kiran, Schadendorf, Dirk

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Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial von Migden, Michael R, Dr, Guminski, Alexander, PhD, Gutzmer, Ralf, Prof, Dirix, Luc, MD, Lewis, Karl D, MD, Combemale, Patrick, MD, Herd, Robert M, MD, Kudchadkar, Ragini, MD, Trefzer, Uwe, Prof, Gogov, Sven, MD, Pallaud, Celine, PhD, Yi, Tingting, PhD, Mone, Manisha, PhD, Kaatz, Martin, MD, Loquai, Carmen, MD, Stratigos, Alexander J, Prof, Schulze, Hans-Joachim, MD, Plummer, Ruth, Prof, Chang, Anne Lynn S, MD, Cornélis, Frank, MD, Lear, John T, MD, Sellami, Dalila, MD, Dummer, Reinhard, Prof

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The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell... von Dummer, Reinhard, MD, Guminski, Alexander, MD, PhD, Gutzmer, Ralf, MD, Dirix, Luc, MD, Lewis, Karl D., MD, Combemale, Patrick, MD, Herd, Robert M., MD, Kaatz, Martin, MD, Loquai, Carmen, MD, Stratigos, Alexander J., MD, Schulze, Hans-Joachim, MD, Plummer, Ruth, MD, Gogov, Sven, MD, Pallaud, Celine, PhD, Yi, Tingting, PhD, Mone, Manisha, PhD, Chang, Anne Lynn S., MD, Cornélis, Frank, MD, Kudchadkar, Ragini, MD, Trefzer, Uwe, MD, Lear, John T., MD, Sellami, Dalila, MD, Migden, Michael R., MD

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Evolving Carbon Nanotube Reservoir Computers von Dale, Matthew, Miller, Julian F., Stepney, Susan, Trefzer, Martin A.

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Results of a multicenter, randomized, double‐blind phase 2/3 study of lenalidomide in the treatment of pretreated relapsed or refractory metastatic malignant melanoma von Eisen, Tim, Trefzer, Uwe, Hamilton, Anne, Hersey, Peter, Millward, Michael, Knight, Robert D., Jungnelius, Jarl U., Glaspy, John

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Efficacy and safety of sonidegib in patients (pts) with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC): BOLT 30-month analysis von Dummer, Reinhard, Migden, Michael Robert, Guminski, Alexander, Gutzmer, Ralf, Kudchadkar, Ragini Reiney, Lewis, Karl D., Dirix, Luc, Combemale, Patrick, Trefzer, Uwe, Loquai, Carmen, Kaatz, Martin, Chang, Anne L. S., Stratigos, Alexander, Plummer, Elizabeth R., Mone, Manisha, Castro, Henry J., Yi, Tingting, Sellami, Dalila B., Lear, John

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The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell... von Dummer, Reinhard, Guminski, Alexander, Gutzmer, Ralf, Dirix, Luc, Lewis, Karl D, Combemale, Patrick, Herd, Robert M, Kaatz, Martin, Loquai, Carmen, Stratigos, Alexander J, Schulze, Hans-Joachim, Plummer, Ruth, Gogov, Sven, Pallaud, Celine, Yi, Tingting, Mone, Manisha, Chang, Anne Lynn S, Cornélis, Frank, Kudchadkar, Ragini, Trefzer, Uwe, Lear, John T, Sellami, Dalila, Migden, Michael R

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Long-term safety and overall survival update for BREAK-2, a phase 2, single-arm, open-label study of dabrafenib in previously treated metastatic melanoma (NCT01153763) von Ascierto, Paolo Antonio, Minor, David R., Ribas, Antoni, Lebbe, Celeste, O'Hagan, Anne, Swann, R. Suzanne, Scheuber, Anita, Schadendorf, Dirk, Kefford, Richard, Grob, Jean Jacques, Hamid, Omid, Schuchter, Lynn Mara, Simeone, Ester, Wilhelm, Tabea, Kim, Kevin, Aktan, Gursel, Trefzer, Uwe

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Coordinated expression of clustered cancer/testis genes encoded in a large inverted repeat DNA structure von Bredenbeck, Anne, Hollstein, Verena M., Trefzer, Uwe, Sterry, Wolfram, Walden, Peter, Losch, Florian O.

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