Solid-Phase Synthesis of Piperazinones via Disrupted Ugi Condensation von Treder, Adam P, Tremblay, Marie-Claude, Yudin, Andrei K, Marsault, Eric

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Solid-Phase Parallel Synthesis of Functionalised Medium-to-Large Cyclic Peptidomimetics through Three-Component Coupling Driven by Aziridine Aldehyde Dimers von Treder, Adam P., Hickey, Jennifer L., Tremblay, Marie-Claude J., Zaretsky, Serge, Scully, Conor C. G., Mancuso, John, Doucet, Annie, Yudin, Andrei K., Marsault, Eric

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New imidazoline/α2-adrenoceptors affecting compounds—4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies von Treder, Adam P., Andruszkiewicz, Ryszard, Zgoda, Włodzimierz, Walkowiak, Aleksandra, Ford, Celeste, Hudson, Alan L.

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New imidazoline/α(2)-adrenoceptors affecting compounds-4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies von Treder, Adam P, Andruszkiewicz, Ryszard, Zgoda, Włodzimierz, Walkowiak, Aleksandra, Ford, Celeste, Hudson, Alan L

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New analogues of agmatine with higher affinity to imidazoline receptors von Treder, Adam P., Andruszkiewicz, Ryszard, Zgoda, Włodzimierz, Ford, Celeste, Hudson, Alan L.

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Abstract 4423: Antitumor activity of the novel oral highly selective Wee1 inhibitor Debio 0123 von O'Dowd, Colin, Gavory, Gerald, Burkamp, Frank, Treder, Adam, Boyd, Caroline, Harrison, Tim, Massière, Frederic, Glück, Astrid, Chardonnens, Christophe, Zaffalon, Andrea, Rigotti, Stefania, Mader, Robert, Vuagniaux, Grégoire, Chessex, Anne Vaslin

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Abstract LB-319: Development and characterization of ADC999 : A novel, potent orally available Wee1 inhibitor with robust antitumor efficacy in vivo von Gavory, Gerald, O'Dowd, Colin, Rozycka, Ewelina, Boyd, Caroline, Gorges, Beronia, McLean, Estelle, Daubriac, Julien, Rountree, Shane, Shepherd, Steven, Burton, Stephanie, McFarland, Mary, Treder, Adam, Wilkinson, Andy, Burkamp, Frank, Harrison, Tim

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Abstract 1935: Accessing the cancer DUBome with UbiPlex: A bespoke drug discovery platform for deubiquitinase enzymes von Gavory, Gerald, O'Dowd, Colin, Barker, Oliver, Bell, Christina, Burkamp, Frank, Burton, Stephanie, Cassidy, Eamon, Costa, Joana, Dossang, Anthony, Helm, Matt, Henderson, Ashling, Hewitt, Peter, Hughes, Caroline, McFarland, Mary, Miel, Hugues, Page, Natalie, Proctor, Lauren, Rountree, Shane, Rozycka, Ewelina, Shepherd, Steven, Treder, Adam, Wappett, Mark, Whitehead, Steven, Harrison, Tim

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Abstract B17: Development of novel, potent orally available Wee1 inhibitors with robust antitumor efficacy in vivo von Gavory, Gerald, O'Dowd, Colin, Rozycka, Ewelina, Boyd, Caroline, Gorges, Beronia, McLean, Estelle, Rountree, Shane, Sheperd, Steven, Burton, Stephanie, McFarland, Mary, Janssen, Dominic, Treder, Adam, Wilkinson, Andy, Burkamp, Frank, Harrison, Tim

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New imidazoline/ alpha sub(2)-adrenoceptors affecting compounds - 4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies von Treder, Adam P, Andruszkiewicz, Ryszard, Zgoda, Wlodzimierz, Walkowiak, Aleksandra, d, Celeste, Hudson, Alan L

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A New Approach to the Synthesis of Selectively Protected (2S)-1,2,4-Triaminobutane Derivatives von Treder, Adam P., Walkowiak, Aleksandra, Zgoda, Włodzimierz, Andruszkiewicz, Ryszard

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HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS von HELM, Matthew, O'DOWD, Colin, CRANSTON, Aaron, BURKAMP, Frank, TREDER, Adam Piotr, ROUNTREE, James Samuel Shane, PROCTOR, Lauren Emma

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A New Approach to the Synthesis of Selectively Protected (2S)-1,2,4-Triaminobutane Derivatives von Treder, Adam P., Walkowiak, Aleksandra, Zgoda, Wlodzimierz, Andruszkiewicz, Ryszard

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HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS von HELM, Matthew, O'DOWD, Colin, CRANSTON, Aaron, BURKAMP, Frank, TREDER, Adam Piotr, ROUNTREE, James Samuel Shane, PROCTOR, Lauren Emma

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4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (USP19) von Rountree, James Samuel Shane, O'Dowd, Colin, Shepherd, Steven David, Treder, Adam Piotr, Proctor, Lauren Emma, Burkamp, Frank, Costa, Joana Rita Castro, Whitehead, Steven Kristopher, Harrison, Timothy

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4-HYDROXYPIPERIDINE DERIVATIVES AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) von SHEPHERD, Steven David, O'DOWD, Colin, HARRISON, Timothy, TREDER, Adam Piotr, BURKAMP, Frank, ROUNTREE, James Samuel Shane, COSTA, Joana Rita Castro, WHITEHEAD, Steven Kristopher, PROCTOR, Lauren Emma

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WEE-1 INHIBITING PYRAZOLOPYRIMIDINONE COMPOUNDS von BURKAMP, Frank, TREDER, Adam Piotr, ROUNTREE, James Samuel Shane

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4-HYDROXYPIPERIDINE DERIVATIVES AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) von SHEPHERD, Steven David, O'DOWD, Colin, HARRISON, Timothy, TREDER, Adam Piotr, BURKAMP, Frank, ROUNTREE, James Samuel Shane, COSTA, Joana Rita Castro, WHITEHEAD, Steven Kristopher, PROCTOR, Lauren Emma

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WEE-1 INHIBITING PYRAZOLOPYRIMIDINONE COMPOUNDS von BURKAMP, Frank, TREDER, Adam Piotr, ROUNTREE, James Samuel Shane

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WEE-1 INHIBITING PYRIDOPYRIMIDINONE COMPOUNDS von BURKAMP, Frank, TREDER, Adam Piotr, ROUNTREE, James Samuel Shane

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