Functional significance of the perforin/granzyme cell death pathway von Trapani, Joseph A, Smyth, Mark J

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Apoptosis induced by the lymphocyte effector molecule perforin von Bolitho, Paul, Voskoboinik, Ilia, Trapani, Joseph A, Smyth, Mark J

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A fresh look at tumor immunosurveillance and immunotherapy von Smyth, Mark J, Godfrey, Dale I, Trapani, Joseph A

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The dual adverse effects of TGF-β secretion on tumor progression von Trapani, Joseph A.

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Granzyme B: pro-apoptotic, antiviral and antitumor functions von Trapani, Joseph A, Sutton, Vivien R

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Suppression of lymphoma and epithelial malignancies effected by interferon gamma von Street, Shayna E A, Trapani, Joseph A, MacGregor, Duncan, Smyth, Mark J

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Extracellular Matrix Remodeling by Human Granzyme B via Cleavage of Vitronectin, Fibronectin, and Laminin von Buzza, Marguerite S., Zamurs, Laura, Sun, Jiuru, Bird, Catherina H., Smith, A. Ian, Trapani, Joseph A., Froelich, Christopher J., Nice, Edouard C., Bird, Phillip I.

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A new quantitative assay for cytochrome c release in apoptotic cells von Waterhouse, N J, Trapani, J A

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A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis von Voskoboinik, Ilia, Thia, Marie-Claude, Trapani, Joseph A.

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Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma von Smyth, M J, Thia, K Y, Street, S E, MacGregor, D, Godfrey, D I, Trapani, J A

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Differential tumor surveillance by natural killer (NK) and NKT cells von Smyth, M J, Thia, K Y, Street, S E, Cretney, E, Trapani, J A, Taniguchi, M, Kawano, T, Pelikan, S B, Crowe, N Y, Godfrey, D I

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Novel mechanisms of apoptosis induced by histone deacetylase inhibitors von PEART, Melissa J, TAINTON, Kellie M, RUEFLI, Astrid A, DEAR, Anthony E, SEDELIES, Karin A, O'REILLY, Lorraine A, WATERHOUSE, Nigel J, TRAPANI, Joseph A, JOHNSTONE, Ricky W

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Calcium-dependent Plasma Membrane Binding and Cell Lysis by Perforin Are Mediated through Its C2 Domain von Voskoboinik, Ilia, Thia, Marie-Claude, Fletcher, Jamie, Ciccone, Annette, Browne, Kylie, Smyth, Mark J., Trapani, Joseph A.

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Adoptive Transfer of T Cells Modified with a Humanized Chimeric Receptor Gene Inhibits Growth of Lewis-Y-Expressing Tumors in Mice von Jennifer A. Westwood, Smyth, Mark J., Michele W. L. Teng, Maria Moeller, Trapani, Joseph A., Scott, Andrew M., Fiona E. Smyth, Glenn A. Cartwright, Barbara E. Power, Dirk Hönemann, H. Miles Prince, Phillip K. Darcy, Michael H. Kershaw

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Caspase Activation by Granzyme B Is Indirect, and Caspase Autoprocessing Requires the Release of Proapoptotic Mitochondrial Factors von Sutton, Vivien R, Wowk, Michelle E, Cancilla, Michael, Trapani, Joseph A

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Cytotoxic Cell Granule-Mediated Apoptosis: Perforin Delivers Granzyme B-Serglycin Complexes into Target Cells without Plasma Membrane Pore Formation von Metkar, Sunil S, Wang, Baikun, Aguilar-Santelises, Miguel, Raja, Srikumar M, Uhlin-Hansen, Lars, Podack, Eckhard, Trapani, Joseph A, Froelich, Christopher J

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation von Sutton, V R, Davis, J E, Cancilla, M, Johnstone, R W, Ruefli, A A, Sedelies, K, Browne, K A, Trapani, J A

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Granzyme M Mediates a Novel Form of Perforin-dependent Cell Death von Kelly, Janice M, Waterhouse, Nigel J, Cretney, Erika, Browne, Kylie A, Ellis, Sarah, Trapani, Joseph A, Smyth, Mark J

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A Central Role for Bid in Granzyme B-induced Apoptosis von Waterhouse, Nigel J., Sedelies, Karin A., Browne, Kylie A., Wowk, Michelle E., Newbold, Andrea, Sutton, Vivien R., Clarke, Chris J. P, Oliaro, Jane, Lindemann, Ralph K., Bird, Phillip I., Johnstone, Ricky W., Trapani, Joseph A.

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Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis von Waterhouse, Nigel J, Sutton, Vivien R, Sedelies, Karin A, Ciccone, Annette, Jenkins, Misty, Turner, Stephen J, Bird, Phillip I, Trapani, Joseph A

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