BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition von Hofmann, Marco H., Gmachl, Michael, Ramharter, Juergen, Savarese, Fabio, Gerlach, Daniel, Marszalek, Joseph R., Sanderson, Michael P., Kessler, Dirk, Trapani, Francesca, Arnhof, Heribert, Rumpel, Klaus, Botesteanu, Dana-Adriana, Ettmayer, Peter, Gerstberger, Thomas, Kofink, Christiane, Wunberg, Tobias, Zoephel, Andreas, Fu, Szu-Chin, Teh, Jessica L., Boettcher, Jark, Pototschnig, Nikolai, Schachinger, Franziska, Schipany, Katharina, Lieb, Simone, Vellano, Christopher P., O'Connell, Jonathan C., Mendes, Rachel L., Moll, Jurgen, Petronczki, Mark, Heffernan, Timothy P., Pearson, Mark, McConnell, Darryl B., Kraut, Norbert

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Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c von Hagiwara, Asami, Cornu, Marion, Cybulski, Nadine, Polak, Pazit, Betz, Charles, Trapani, Francesca, Terracciano, Luigi, Heim, Markus H., Rüegg, Markus A., Hall, Michael N.

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Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer von Hodgkinson, Cassandra L, Morrow, Christopher J, Li, Yaoyong, Metcalf, Robert L, Rothwell, Dominic G, Trapani, Francesca, Polanski, Radoslaw, Burt, Deborah J, Simpson, Kathryn L, Morris, Karen, Pepper, Stuart D, Nonaka, Daisuke, Greystoke, Alastair, Kelly, Paul, Bola, Becky, Krebs, Matthew G, Antonello, Jenny, Ayub, Mahmood, Faulkner, Suzanne, Priest, Lynsey, Carter, Louise, Tate, Catriona, Miller, Crispin J, Blackhall, Fiona, Brady, Ged, Dive, Caroline

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CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer von Weiskopf, Kipp, Jahchan, Nadine S, Schnorr, Peter J, Cristea, Sandra, Ring, Aaron M, Maute, Roy L, Volkmer, Anne K, Volkmer, Jens-Peter, Liu, Jie, Lim, Jing Shan, Yang, Dian, Seitz, Garrett, Nguyen, Thuyen, Wu, Di, Jude, Kevin, Guerston, Heather, Barkal, Amira, Trapani, Francesca, George, Julie, Poirier, John T, Gardner, Eric E, Miles, Linde A, de Stanchina, Elisa, Lofgren, Shane M, Vogel, Hannes, Winslow, Monte M, Dive, Caroline, Thomas, Roman K, Rudin, Charles M, van de Rijn, Matt, Majeti, Ravindra, Garcia, K Christopher, Weissman, Irving L, Sage, Julien

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Vasculogenic mimicry in small cell lung cancer von Williamson, Stuart C., Metcalf, Robert L., Trapani, Francesca, Mohan, Sumitra, Antonello, Jenny, Abbott, Benjamin, Leong, Hui Sun, Chester, Christopher P. E., Simms, Nicole, Polanski, Radoslaw, Nonaka, Daisuke, Priest, Lynsey, Fusi, Alberto, Carlsson, Fredrika, Carlsson, Anders, Hendrix, Mary J. C., Seftor, Richard E. B., Seftor, Elisabeth A., Rothwell, Dominic G., Hughes, Andrew, Hicks, James, Miller, Crispin, Kuhn, Peter, Brady, Ged, Simpson, Kathryn L., Blackhall, Fiona H., Dive, Caroline

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Activity of the Monocarboxylate Transporter 1 Inhibitor AZD3965 in Small Cell Lung Cancer von POLANSKI, Radostaw, HODGKINSON, Cassandra L, SMITH, Paul D, BLACKHALL, Fiona, DIVE, Caroline, MORROW, Christopher J, FUSI, Alberto, NONAKA, Daisuke, PRIEST, Lynsey, KELLY, Paul, TRAPANI, Francesca, BISHOP, Paul W, WHITE, Anne, CRITCHLOW, Susan E

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Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21 von Cornu, Marion, Oppliger, Wolfgang, Albert, Verena, Robitaille, Aaron M., Trapani, Francesca, Quagliata, Luca, Fuhrer, Tobias, Sauer, Uwe, Terracciano, Luigi, Hall, Michael N.

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Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04 von Brecht, Karin, Kirchhofer, Carla, Bouitbir, Jamal, Trapani, Francesca, Keiser, Jennifer, Krähenbühl, Stephan

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A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity von Simpson, Kathryn L., Stoney, Ruth, Frese, Kristopher K., Simms, Nicole, Rowe, William, Pearce, Simon P., Humphrey, Sam, Booth, Laura, Morgan, Derrick, Dynowski, Marek, Trapani, Francesca, Catozzi, Alessia, Revill, Mitchell, Helps, Thomas, Galvin, Melanie, Girard, Luc, Nonaka, Daisuke, Carter, Louise, Krebs, Matthew G., Cook, Natalie, Carter, Mathew, Priest, Lynsey, Kerr, Alastair, Gazdar, Adi F., Blackhall, Fiona, Dive, Caroline

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Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer von Jahchan, Nadine S., Lim, Jing Shan, Bola, Becky, Morris, Karen, Seitz, Garrett, Tran, Kim Q., Xu, Lei, Trapani, Francesca, Morrow, Christopher J., Cristea, Sandra, Coles, Garry L., Yang, Dian, Vaka, Dedeepya, Kareta, Michael S., George, Julie, Mazur, Pawel K., Nguyen, Thuyen, Anderson, Wade C., Dylla, Scott J., Blackhall, Fiona, Peifer, Martin, Dive, Caroline, Sage, Julien

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Potential Aroma Chemical Fingerprint of Oxidised Coffee Note by HS-SPME-GC-MS and Machine Learning von Strocchi, Giulia, Bagnulo, Eloisa, Ruosi, Manuela R, Ravaioli, Giulia, Trapani, Francesca, Bicchi, Carlo, Pellegrino, Gloria, Liberto, Erica

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Corrigendum to “HMGA1 expression in human hepatocellular carcinoma correlates with poor prognosis and promotes tumor growth and migration in in vitro models” [Neoplasia 18 (2016) 7... von Andreozzi, Mariacarla, Quintavalle, Cristina, Benz, David, Quagliata, Luca, Matter, Matthias, Calabrese, Diego, Tosti, Nadia, Ruiz, Christian, Trapani, Francesca, Tornillo, Luigi, Fusco, Alfredo, Heim, Markus H., Ng, Charlotte K.Y., Pallante, Pierlorenzo, Terracciano, Luigi M., Piscuoglio, Salvatore

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Exploring the Potential of Lactic Acid Fermentation for the Recovery of Exhausted Vanilla Beans von Hadj Saadoun, Jasmine, Levante, Alessia, Ferrillo, Antonio, Trapani, Francesca, Bernini, Valentina, Galaverna, Gianni, Neviani, Erasmo, Lazzi, Camilla

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Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma von Lehmann, Frank Serge, Trapani, Francesca, Fueglistaler, Ida, Terracciano, Luigi Maria, von Flüe, Markus, Cathomas, Gieri, Zettl, Andreas, Benkert, Pascal, Oertli, Daniel, Beglinger, Christoph

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Role of serotonergic system in the pathogenesis of fibrosis in canine idiopathic inflammatory myopathies von Pavone, Luigi Michele, Rea, Silvana, Trapani, Francesca, De Pasquale, Valeria, Tafuri, Simona, Papparella, Serenella, Paciello, Orlando

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Therapeutic impact of BET inhibitor BI 894999 treatment: backtranslation from the clinic von Tontsch-Grunt, Ulrike, Traexler, Paula-Elena, Baum, Anke, Musa, Hanny, Marzin, Kristell, Wang, Shaonan, Trapani, Francesca, Engelhardt, Harald, Solca, Flavio

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A Bispecific DLL3/CD3 IgG-Like T-Cell Engaging Antibody Induces Antitumor Responses in Small Cell Lung Cancer von Hipp, Susanne, Voynov, Vladimir, Drobits-Handl, Barbara, Giragossian, Craig, Trapani, Francesca, Nixon, Andrew E., Scheer, Justin M., Adam, Paul J.

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The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer von Lallo, Alice, Frese, Kristopher K, Morrow, Christopher J, Sloane, Robert, Gulati, Sakshi, Schenk, Maximillian W, Trapani, Francesca, Simms, Nicole, Galvin, Melanie, Brown, Stewart, Hodgkinson, Cassandra L, Priest, Lynsey, Hughes, Adina, Lai, Zhongwu, Cadogan, Elaine, Khandelwal, Garima, Simpson, Kathryn L, Miller, Crispin, Blackhall, Fiona, O'Connor, Mark J, Dive, Caroline

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Abstract 1083: MEKi and SOS1i as a combination treatment option for KRAS mutant endometrial cancer von Kostyrko, Kaja, Hinkel, Melanie, Hofmann, Marco H., Trapani, Francesca

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Pharmacodynamic and Antitumor Activity of BI 836880, a Dual Vascular Endothelial Growth Factor and Angiopoietin 2 Inhibitor, Alone and Combined with Programmed Cell Death Protein-1... von Hofmann, Irmgard, Baum, Anke, Hofmann, Marco H, Trapani, Francesca, Reichel-Voda, Claudia, Ehrensperger, Diane, Aichinger, Martin, Ebner, Florian, Budano, Nicole, Schweifer, Norbert, Sykora, Martina, Depla, Erik, Boucneau, Joachim, Gschwind, Andreas, Kraut, Norbert, Hilberg, Frank, Künkele, Klaus-Peter

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