A Refined 3-Dimensional QSAR of Cytochrome P450 2C9:  Computational Predictions of Drug Interactions von Rao, Sreedhara, Aoyama, Ron, Schrag, Michael, Trager, William F, Rettie, Allan, Jones, Jeffrey P

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Oxidation of Acetaminophen to Its Toxic Quinone Imine and Nontoxic Catechol Metabolites by Baculovirus-Expressed and Purified Human Cytochromes P450 2E1 and 2A6 von Chen, Weiqiao, Koenigs, Luke L, Thompson, Stella J, Peter, Raimund M, Rettie, Allan E, Trager, William F, Nelson, Sidney D

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Mechanism-Based Inactivation of P450 2A6 by Furanocoumarins von Koenigs, Luke L, Trager, William F

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Mechanism-Based Inactivation of Cytochrome P450 2B1 by 8-Methoxypsoralen and Several Other Furanocoumarins von Koenigs, Luke L, Trager, William F

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Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline von Kunze, Kent L, Trager, William F

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions von Rettie, Allan E, Korzekwa, Kenneth R, Kunze, Kent L, Lawrence, Ross F, Eddy, A Craig, Aoyama, Toshifumi, Gelboin, Harry V, Gonzalez, Frank J, Trager, William F

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Electrospray Ionization Mass Spectrometric Analysis of Intact Cytochrome P450:  Identification of Tienilic Acid Adducts to P450 2C9 von Koenigs, Luke L, Peter, Raimund M, Hunter, Ann P, Haining, Robert L, Rettie, Allan E, Friedberg, Thomas, Pritchard, Michael P, Shou, Magang, Rushmore, Thomas H, Trager, William F

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Photoaffinity labeling of P450Cam by an imidazole-tethered benzophenone probe von Trnka, Michael J, Doneanu, Catalin E, Trager, William F

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Allelic Variants of Human Cytochrome P450 2C9: Baculovirus-Mediated Expression, Purification, Structural Characterization, Substrate Stereoselectivity, and Prochiral Selectivity of... von Haining, Robert L., Hunter, Ann P., Veronese, Maurice E., Trager, William F., Rettie, Allan E.

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Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors von Suzuki, Hisashi, Kneller, M.Byron, Rock, Dan A, Jones, Jeffrey P, Trager, William F, Rettie, Allan E

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Fluvoxamine-theophylline interaction: Gap between in vitro and in vivo inhibition constants toward cytochrome P4501A2 von Yao, Caiping, Kunze, Kent L., Kharasch, Evan D., Wang, Yi, Trager, William F., Ragueneau, Isabelle, Levy, René H.

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Enzymatic Determinants of the Substrate Specificity of CYP2C9:  Role of B‘−C Loop Residues in Providing the π-Stacking Anchor Site for Warfarin Binding von Haining, Robert L, Jones, Jeffrey P, Henne, Kirk R, Fisher, Michael B, Koop, Dennis R, Trager, William F, Rettie, Allan E

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Mechanism-Based Inactivation of Cytochrome P450 3A4 by L-754,394 von Lightning, Luke Koenigs, Jones, Jeffrey P, Friedberg, Thomas, Pritchard, Michael P, Shou, Magang, Rushmore, Thomas H, Trager, William F

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Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: In vitro and in vivo comparison and calculation of in vivo inhibition constants von Tran, Agnès, Rey, Elisabeth, Pons, Gérard, Rousseau, Marina, d'Athis, Philippe, Olive, Georges, Mather, Gary G., Bishop, Frances E., Wurden, Colleen J., Labroo, Rita, Trager, William F., Kunze, Kent L., Thummel, Kenneth E., Vincent, Jean C., Gillardin, Jean‐Marie, Lepage, Francis, Levy, René H.

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Active Site Characteristics of CYP4B1 Probed with Aromatic Ligands von Henne, Kirk R, Fisher, Michael B, Iyer, Krishna R, Lang, Dieter H, Trager, William F, Rettie, Allan E

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Characterization of covalent adducts to intact cytochrome P450s by mass spectrometry von Lightning, Luke K., Trager, William F.

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Intramolecular Isotope Effects for Benzylic Hydroxylation of Isomeric Xylenes and 4,4‘-Dimethylbiphenyl by Cytochrome P450:  Relationship between Distance of Methyl Groups and Mask... von Iyer, Krishna R, Jones, Jeffrey P, Darbyshire, John F, Trager, William F

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Experimental and Theoretical Study of the Effect of Active-Site Constrained Substrate Motion on the Magnitude of the Observed Intramolecular Isotope Effect for the P450 101 Catalyz... von Audergon, Christian, Iyer, Krishna R, Jones, Jeffrey P, Darbyshire, John F, Trager, William F

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The preferred solution conformation of warfarin at the active site of cytochrome P-450 based on the CD spectra in octanol/water model system von Heimark, Larry D, Trager, William F

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The binding and regioselectivity of reaction of (R)- and (S)-nicotine with cytochrome P-450cam: parallel experimental and theoretical studies von Jones, Jeffrey P, Trager, William F, Carlson, Timothy J

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