Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients von Sachdeo, R. C., Sachdeo, S. K., Levy, R. H., Streeter, A. J., Bishop, F. E., Kunze, K. L., Mather, G. G., Roskos, L. K., Shen, D. D., Thummel, K. E., Trager, W. F., Curtin, C. R., Doose, Dennis R., Gisclon, L. G., Bialer, Meir

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions von Rettie, Allan E, Korzekwa, Kenneth R, Kunze, Kent L, Lawrence, Ross F, Eddy, A Craig, Aoyama, Toshifumi, Gelboin, Harry V, Gonzalez, Frank J, Trager, William F

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Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline von Kunze, Kent L, Trager, William F

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A Refined 3-Dimensional QSAR of Cytochrome P450 2C9:  Computational Predictions of Drug Interactions von Rao, Sreedhara, Aoyama, Ron, Schrag, Michael, Trager, William F, Rettie, Allan, Jones, Jeffrey P

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Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: In vitro and in vivo comparison and calculation of in vivo inhibition constants von Tran, Agnès, Rey, Elisabeth, Pons, Gérard, Rousseau, Marina, d'Athis, Philippe, Olive, Georges, Mather, Gary G., Bishop, Frances E., Wurden, Colleen J., Labroo, Rita, Trager, William F., Kunze, Kent L., Thummel, Kenneth E., Vincent, Jean C., Gillardin, Jean‐Marie, Lepage, Francis, Levy, René H.

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Active Site Characteristics of CYP4B1 Probed with Aromatic Ligands von Henne, Kirk R, Fisher, Michael B, Iyer, Krishna R, Lang, Dieter H, Trager, William F, Rettie, Allan E

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Oxidation of Acetaminophen to Its Toxic Quinone Imine and Nontoxic Catechol Metabolites by Baculovirus-Expressed and Purified Human Cytochromes P450 2E1 and 2A6 von Chen, Weiqiao, Koenigs, Luke L, Thompson, Stella J, Peter, Raimund M, Rettie, Allan E, Trager, William F, Nelson, Sidney D

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Mechanism-Based Inactivation of P450 2A6 by Furanocoumarins von Koenigs, Luke L, Trager, William F

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Mechanism-Based Inactivation of Cytochrome P450 2B1 by 8-Methoxypsoralen and Several Other Furanocoumarins von Koenigs, Luke L, Trager, William F

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Allelic Variants of Human Cytochrome P450 2C9: Baculovirus-Mediated Expression, Purification, Structural Characterization, Substrate Stereoselectivity, and Prochiral Selectivity of... von Haining, Robert L., Hunter, Ann P., Veronese, Maurice E., Trager, William F., Rettie, Allan E.

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Structural Forms of Phenprocoumon and Warfarin That Are Metabolized at the Active Site of CYP2C9 von He, Minxia, Korzekwa, Kenneth R., Jones, Jeffrey P., Rettie, Allan E., Trager, William F.

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Electrospray Ionization Mass Spectrometric Analysis of Intact Cytochrome P450:  Identification of Tienilic Acid Adducts to P450 2C9 von Koenigs, Luke L, Peter, Raimund M, Hunter, Ann P, Haining, Robert L, Rettie, Allan E, Friedberg, Thomas, Pritchard, Michael P, Shou, Magang, Rushmore, Thomas H, Trager, William F

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Lack of Effect of Azelastine and Ketoconazole Coadministration on Electrocardiographic Parameters in Healthy Volunteers von Morganroth, J., Lyness, W. H., Perhach, J. L., Mather, G. G., Harr, J. E., Trager, W. F., Levy, R. H., Rosenberg, A.

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Enzymatic Determinants of the Substrate Specificity of CYP2C9:  Role of B‘−C Loop Residues in Providing the π-Stacking Anchor Site for Warfarin Binding von Haining, Robert L, Jones, Jeffrey P, Henne, Kirk R, Fisher, Michael B, Koop, Dennis R, Trager, William F, Rettie, Allan E

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Racemates versus enantiomers in drug development: Dogmatism or pragmatism? von Testa, Bernard, Trager, William F.

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Mechanism-Based Inactivation of Cytochrome P450 3A4 by L-754,394 von Lightning, Luke Koenigs, Jones, Jeffrey P, Friedberg, Thomas, Pritchard, Michael P, Shou, Magang, Rushmore, Thomas H, Trager, William F

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Inactivation of multiple hepatic cytochrome P-450 isozymes in rats by allylisopropylacetamide: mechanistic implications von BORNHEIM, L. M, UNDERWOOD, M. C, CALDERA, P, RETTIE, A. E, TRAGER, W. F, WRIGHTON, S. A, CORREIA, M. A

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Theory for the observed isotope effects from enzymatic systems that form multiple products via branched reaction pathways: cytochrome P-450 von KORZEKWA, K. R, TRAGER, W. F, GILLETTE, J. R

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Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450-catalyzed hydroxylation of octane is isozyme independent von Jones, Jeffrey P, Rettie, Allan E, Trager, William F

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Studies on the mechanism of aromatase and other cytochrome P450 mediated deformylation reactions von Korzekwa, Kenneth R., Trager, William F., Mancewicz, Julie, Osawa, Yoichi

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