The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer von O'Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio

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Perspectives on the Biological Role of Chemokine:Glycosaminoglycan Interactions von Handel, Tracy M., Dyer, Douglas P.

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Chemokine: receptor structure, interactions, and antagonism von Allen, Samantha J, Crown, Susan E, Handel, Tracy M

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Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis von Stephens, Bryan S, Ngo, Tony, Kufareva, Irina, Handel, Tracy M

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Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding von Gustavsson, Martin, Dyer, Douglas P, Zhao, Chunxia, Handel, Tracy M

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Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System von Proudfoot, Amanda E I, Johnson, Zoë, Bonvin, Pauline, Handel, Tracy M

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The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions von Dyer, Douglas P., Salanga, Catherina L., Johns, Scott C., Valdambrini, Elena, Fuster, Mark M., Milner, Caroline M., Day, Anthony J., Handel, Tracy M.

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Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices von Wescott, Melanie P., Kufareva, Irina, Paes, Cheryl, Goodman, Jason R., Thaker, Yana, Puffer, Bridget A., Berdougo, Eli, Rucker, Joseph B., Handel, Tracy M., Doranz, Benjamin J.

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Structural basis of ligand interaction with atypical chemokine receptor 3 von Gustavsson, Martin, Wang, Liwen, van Gils, Noortje, Stephens, Bryan S., Zhang, Penglie, Schall, Thomas J., Yang, Sichun, Abagyan, Ruben, Chance, Mark R., Kufareva, Irina, Handel, Tracy M.

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Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity von Ngo, Tony, Stephens, Bryan S, Gustavsson, Martin, Holden, Lauren G, Abagyan, Ruben, Handel, Tracy M, Kufareva, Irina

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Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment von O'Hayre, Morgan, Salanga, Catherina L, Handel, Tracy M, Allen, Samantha J

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Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: Molecular modeling and experimental validation von Kufareva, Irina, Stephens, Bryan S, Holden, Lauren G, Qin, Ling, Zhao, Chunxia, Kawamura, Tetsuya, Abagyan, Ruben, Handel, Tracy M

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Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data von Wang, Xu, Watson, Caroline, Sharp, Joshua S., Handel, Tracy M., Prestegard, James H.

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Interactions of the Chemokine CCL5/RANTES with Medium-Sized Chondroitin Sulfate Ligands von Deshauer, Courtney, Morgan, Ashli M., Ryan, Eathen O., Handel, Tracy M., Prestegard, James H., Wang, Xu

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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors von Gray, Anna L., Karlsson, Richard, Roberts, Abigail R.E., Ridley, Amanda J.L., Pun, Nabina, Khan, Bakhtbilland, Lawless, Craig, Luís, Rafael, Szpakowska, Martyna, Chevigné, Andy, Hughes, Catherine E., Medina-Ruiz, Laura, Birchenough, Holly L., Mulholland, Iashia Z., Salanga, Catherina L., Yates, Edwin A., Turnbull, Jeremy E., Handel, Tracy M., Graham, Gerard J., Jowitt, Thomas A., Schiessl, Ingo, Richter, Ralf P., Miller, Rebecca L., Dyer, Douglas P.

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A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling von Grimsey, Neil J., Narala, Rachan, Rada, Cara C., Mehta, Sohum, Stephens, Bryan S., Kufareva, Irina, Lapek, John, Gonzalez, David J., Handel, Tracy M., Zhang, Jin, Trejo, JoAnn

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Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis von O'Hayre, Morgan, Salanga, Catherina L, Kipps, Thomas J, Messmer, Davorka, Dorrestein, Pieter C, Handel, Tracy M

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Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis von Zabel, Brian A, Nakae, Susumu, Zúñiga, Luis, Kim, Ji-Yun, Ohyama, Takao, Alt, Carsten, Pan, Junliang, Suto, Hajime, Soler, Dulce, Allen, Samantha J, Handel, Tracy M, Song, Chang Ho, Galli, Stephen J, Butcher, Eugene C

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On-bead purification and nanodisc reconstitution of human chemokine receptor complexes for structural and biophysical studies von Gu, Siyi, Huang, Mian, Handel, Tracy M.

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Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice von Axelsson, Jakob, Xu, Ding, Na Kang, Bit, Nussbacher, Julia K., Handel, Tracy M., Ley, Klaus, Sriramarao, P., Esko, Jeffrey D.

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