The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors von Rinaldi, Jacob, Sokol, Ethan S, Hartmaier, Ryan J, Trabucco, Sally E, Frampton, Garrett M, Goldberg, Michael E, Albacker, Lee A, Daemen, Anneleen, Manning, Gerard

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A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient S... von Trabucco, Sally E., Gowen, Kyle, Maund, Sophia L., Sanford, Eric, Fabrizio, David A., Hall, Michael J., Yakirevich, Evgeny, Gregg, Jeffrey P., Stephens, Phil J., Frampton, Garrett M., Hegde, Priti S., Miller, Vincent A., Ross, Jeffrey S., Hartmaier, Ryan J., Huang, Shih-Min A., Sun, James X.

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Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients von Fernando, Tharu M., Piskol, Robert, Bainer, Russell, Sokol, Ethan S., Trabucco, Sally E., Zhang, Qing, Trinh, Huong, Maund, Sophia, Kschonsak, Marc, Chaudhuri, Subhra, Modrusan, Zora, Januario, Thomas, Yauch, Robert L.

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Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma von Trabucco, Sally E, Gerstein, Rachel M, Evens, Andrew M, Bradner, James E, Shultz, Leonard D, Greiner, Dale L, Zhang, Hong

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Finding Shangri-La: Limiting the Impact of Senescence on Aging von Trabucco, Sally E., Zhang, Hong

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YY1 Regulates the Germinal Center Reaction by Inhibiting Apoptosis von Trabucco, Sally E, Gerstein, Rachel M, Zhang, Hong

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Real-World Clinical Performance of a DNA-Based Comprehensive Genomic Profiling Assay for Detecting Targetable Fusions in Nonsquamous NSCLC von Mack, Philip C, Keller-Evans, Rachel B, Li, Gerald, Lofgren, Katherine T, Schrock, Alexa B, Trabucco, Sally E, Allen, Justin M, Tolba, Khaled, Oxnard, Geoffrey R, Huang, Richard S P

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Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2-, PIK3CA-mutated breast cancers von Hutchinson, Katherine E, Chen, Jessica W, Savage, Heidi M, Stout, Thomas J, Schimmoller, Frauke, Cortés, Javier, Dent, Susan, Harbeck, Nadia, Jacot, William, Krop, Ian, Trabucco, Sally E, Sivakumar, Smruthy, Sokol, Ethan S, Wilson, Timothy R

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A clinico-genomic analysis of soft tissue sarcoma patients reveals CDKN2A deletion as a biomarker for poor prognosis von Bui, Nam Q, Przybyl, Joanna, Trabucco, Sally E, Frampton, Garrett, Hastie, Trevor, van de Rijn, Matt, Ganjoo, Kristen N

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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations von Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D., Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar

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Smurf2 regulates hematopoietic stem cell self‐renewal and aging von Ramkumar, Charusheila, Kong, Yahui, Trabucco, Sally E., Gerstein, Rachel M., Zhang, Hong

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Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors von Riess, Jonathan W., Rahman, Shaila, Kian, Waleed, Edgerly, Claire, Heilmann, Andreas M., Madison, Russell, Ramkissoon, Shakti H., Klaitman, Shai Shlomi, Chung, Jon H., Trabucco, Sally E., Jin, Dexter X., Alexander, Brian M., Klempner, Samuel J., Albacker, Lee A., Frampton, Garrett M., Roisman, Laila C., Miller, Vincent A., Ross, Jeffrey S., Schrock, Alexa B., Gregg, Jeffrey P., Peled, Nir, Sokol, Ethan S., Ali, Siraj M.

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Prediction and characterization of diffuse large B-cell lymphoma cell-of-origin subtypes using targeted sequencing von Trabucco, Sally E, Sokol, Ethan S, Maund, Sophia L, Moore, Jay A, Frampton, Garrett M, Albacker, Lee A, Oestergaard, Mikkel Z, Venstrom, Jeffrey, Sehn, Laurie H, Bolen, Christopher R

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Integrated DNA/RNA targeted genomic profiling of diffuse large B-cell lymphoma using a clinical assay von Intlekofer, Andrew M., Joffe, Erel, Batlevi, Connie L., Hilden, Patrick, He, Jie, Seshan, Venkatraman E., Zelenetz, Andrew D., Palomba, M. Lia, Moskowitz, Craig H., Portlock, Carol, Straus, David J., Noy, Ariela, Horwitz, Steven M., Gerecitano, John F., Moskowitz, Alison, Hamlin, Paul, Matasar, Matthew J, Kumar, Anita, van den Brink, Marcel R., Knapp, Kristina M., Pichardo, Janine D., Nahas, Michelle K., Trabucco, Sally E., Mughal, Tariq, Copeland, Amanda R., Papaemmanuil, Elli, Moarii, Mathai, Levine, Ross L., Dogan, Ahmet, Miller, Vincent A., Younes, Anas

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Abstract 2496: YY1 regulates the germinal center reaction by inhibiting apoptosis von Trabucco, Sally E., Zhang, Hong

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Abstract IA30: Dissecting the playbook of cancer: Genomic analysis of 100,000 human tumors reveals elaborate patterns of activation of the RTK-RAS-MAPK pathway von Manning, Gerard, Lounsbury, Nick, Hartmaier, Ryan, Trabucco, Sally, Sokol, Ethan

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Primary Adult Retroperitoneal Sarcoma: A Comprehensive Genomic Profiling Study von Necchi, Andrea, Basile, Giuseppe, Pederzoli, Filippo, Bandini, Marco, Grivas, Petros, Bratslavsky, Gennady, Spiess, Philippe E., Killian, J. Keith, Lin, Douglas I., Williams, Erik, Ramkissoon, Shakti, Severson, Eric A., Alexander, Brian M., Venstrom, Jeffrey, Reddy, Prasanth, McGregor, Kimberly, Elvin, Julia A., Schrock, Alexa B., Pavlick, Dean C., Jin, Dexter X., Trabucco, Sally E., Danziger, Natalie, Ross, Jeffrey S.

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Abstract 3538: Microsatellite instability (MSI) and homologous recombination deficiency (HRD) are mutually exclusive mechanisms of genomic instability von Jin, Dexter X., Sokol, Ethan S., Trabucco, Sally E., Frampton, Garrett M., Molinero, Luciana

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Abstract PR03: Dissecting the playbook of cancer: Genomic analysis of 100,000 human tumors reveals elaborate patterns of activation of the RTK-RAS-MAPK pathway von Manning, Gerard, Lounsbury, Nicholas, Hartmaier, Ryan, Trabucco, Sally, Sokol, Ethan, Rinaldi, Jacob, Liu, Jinfeng, Gnad, Florian

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Abstract B37: Dissecting the playbook of cancer: Genomic analysis of 100,000 human tumors reveals elaborate patterns of activation of the RTK-RAS-MAPK pathway von Manning, Gerard, Lounsbury, Nicholas, Hartmaier, Ryan, Trabucco, Sally, Sokol, Ethan, Rinaldi, Jacob, Liu, Jinfeng, Gnad, Florian

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