Recurrent hyperactive ESR1 fusion proteins in endocrine therapy-resistant breast cancer von Hartmaier, R.J., Trabucco, S.E., Priedigkeit, N., Chung, J.H., Parachoniak, C.A., Vanden Borre, P., Morley, S., Rosenzweig, M., Gay, L.M., Goldberg, M.E., Suh, J., Ali, S.M., Ross, J., Leyland-Jones, B., Young, B., Williams, C., Park, B., Tsai, M., Haley, B., Peguero, J., Callahan, R.D., Sachelarie, I., Cho, J., Atkinson, J.M., Bahreini, A., Nagle, A.M., Puhalla, S.L., Watters, R.J., Erdogan-Yildirim, Z., Cao, L., Oesterreich, S., Mathew, A., Lucas, P.C., Davidson, N.E., Brufsky, A.M., Frampton, G.M., Stephens, P.J., Chmielecki, J., Lee, A.V.

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443PDGenomic characteristics and predicted ancestry of NTRK1/2/3 and ROS1 fusion-positive tumours from >165,000 pan-solid tumours von Wilson, T R, Sokol, E S, Trabucco, S E, Newberg, J Y, Simmons, B, Riehl, T, Maund, S L

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1549PNTRK1-3 genomic fusions in non-small cell lung cancer (NSCLC) determined by comprehensive genomic profiling von Ou, S-H I, Sokol, E S, Trabucco, S E, Jin, D X, Frampton, G M, Graziano, S L, Elvin, J A, Vergilio, J-A, Killian, J K, Ngo, N, Lin, D, Ramkissoon, S, Severson, E, Ali, S M, Schrock, A B, Chung, J, Reddy, P, McGregor, K, Alexander, B M, Ross, J S

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Efficacy and safety of cannabinoid oromucosal spray for multiple sclerosis spasticity von Patti, F, Messina, S, Solaro, C, Amato, M P, Bergamaschi, R, Bonavita, S, Bruno Bossio, R, Brescia Morra, V, Costantino, G F, Cavalla, P, Centonze, D, Comi, G, Cottone, S, Danni, M, Francia, A, Gajofatto, A, Gasperini, C, Ghezzi, A, Iudice, A, Lus, G, Maniscalco, G T, Marrosu, M G, Matta, M, Mirabella, M, Montanari, E, Pozzilli, C, Rovaris, M, Sessa, E, Spitaleri, D, Trojano, M, Valentino, P, Zappia, M

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Cost-Effectiveness Analysis of Cannabinoid Oromucosal Spray Use for the Management of Spasticity in Subjects with Multiple Sclerosis von Mantovani, Lorenzo G., Cozzolino, Paolo, Cortesi, Paolo A., Patti, Francesco

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An Arabidopsis gene regulatory network for secondary cell wall synthesis von Taylor-Teeples, M., Lin, L., de Lucas, M., Turco, G., Toal, T. W., Gaudinier, A., Young, N. F., Trabucco, G. M., Veling, M. T., Lamothe, R., Handakumbura, P. P., Xiong, G., Wang, C., Corwin, J., Tsoukalas, A., Zhang, L., Ware, D., Pauly, M., Kliebenstein, D. J., Dehesh, K., Tagkopoulos, I., Breton, G., Pruneda-Paz, J. L., Ahnert, S. E., Kay, S. A., Hazen, S. P., Brady, S. M.

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The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors von Rinaldi, Jacob, Sokol, Ethan S, Hartmaier, Ryan J, Trabucco, Sally E, Frampton, Garrett M, Goldberg, Michael E, Albacker, Lee A, Daemen, Anneleen, Manning, Gerard

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A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient S... von Trabucco, Sally E., Gowen, Kyle, Maund, Sophia L., Sanford, Eric, Fabrizio, David A., Hall, Michael J., Yakirevich, Evgeny, Gregg, Jeffrey P., Stephens, Phil J., Frampton, Garrett M., Hegde, Priti S., Miller, Vincent A., Ross, Jeffrey S., Hartmaier, Ryan J., Huang, Shih-Min A., Sun, James X.

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Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma von Trabucco, Sally E, Gerstein, Rachel M, Evens, Andrew M, Bradner, James E, Shultz, Leonard D, Greiner, Dale L, Zhang, Hong

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Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients von Fernando, Tharu M., Piskol, Robert, Bainer, Russell, Sokol, Ethan S., Trabucco, Sally E., Zhang, Qing, Trinh, Huong, Maund, Sophia, Kschonsak, Marc, Chaudhuri, Subhra, Modrusan, Zora, Januario, Thomas, Yauch, Robert L.

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Depressive Symptoms Correlate with Disability and Disease Course in Multiple Sclerosis Patients: An Italian Multi-Center Study Using the Beck Depression Inventory von Solaro, C, Trabucco, E, Signori, A, Martinelli, V, Radaelli, M, Centonze, D, Rossi, S, Grasso, M G, Clemenzi, A, Bonavita, S, D'Ambrosio, A, Patti, F, D'Amico, E, Cruccu, G, Truini, A

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Pain and Multiple Sclerosis: Pathophysiology and Treatment von Solaro, Claudio, Trabucco, Erika, Messmer Uccelli, Michele

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Finding Shangri-La: Limiting the Impact of Senescence on Aging von Trabucco, Sally E., Zhang, Hong

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Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2-, PIK3CA-mutated breast cancers von Hutchinson, Katherine E, Chen, Jessica W, Savage, Heidi M, Stout, Thomas J, Schimmoller, Frauke, Cortés, Javier, Dent, Susan, Harbeck, Nadia, Jacot, William, Krop, Ian, Trabucco, Sally E, Sivakumar, Smruthy, Sokol, Ethan S, Wilson, Timothy R

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Abstract 2496: YY1 regulates the germinal center reaction by inhibiting apoptosis von Trabucco, Sally E., Zhang, Hong

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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations von Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D., Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar

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Preimplantation genetic diagnosis for aneuploidy testing in women older than 44 years: a multicenter experience von Ubaldi, Filippo Maria, M.D., M.Sc, Cimadomo, Danilo, M.Sc, Capalbo, Antonio, Ph.D, Vaiarelli, Alberto, M.D., Ph.D, Buffo, Laura, M.D, Trabucco, Elisabetta, M.D, Ferrero, Susanna, M.D, Albani, Elena, M.Sc, Rienzi, Laura, M.Sc, Levi Setti, Paolo E., M.D

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YY1 Regulates the Germinal Center Reaction by Inhibiting Apoptosis von Trabucco, Sally E, Gerstein, Rachel M, Zhang, Hong

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A clinico-genomic analysis of soft tissue sarcoma patients reveals CDKN2A deletion as a biomarker for poor prognosis von Bui, Nam Q, Przybyl, Joanna, Trabucco, Sally E, Frampton, Garrett, Hastie, Trevor, van de Rijn, Matt, Ganjoo, Kristen N

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Real-World Clinical Performance of a DNA-Based Comprehensive Genomic Profiling Assay for Detecting Targetable Fusions in Nonsquamous NSCLC von Mack, Philip C, Keller-Evans, Rachel B, Li, Gerald, Lofgren, Katherine T, Schrock, Alexa B, Trabucco, Sally E, Allen, Justin M, Tolba, Khaled, Oxnard, Geoffrey R, Huang, Richard S P

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