SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation von Hasee, Abdul, Kc, Ranjan, Angelozzi, Marco, de Charleroy, Charles, Rux, Danielle, Tower, Robert J., Yao, Lutian, da Silva, Renata Pellegrino, Pacifici, Maurizio, Qin, Ling, Lefebvre, Véronique

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Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment von Zhong, Leilei, Yao, Lutian, Tower, Robert J, Wei, Yulong, Miao, Zhen, Park, Jihwan, Shrestha, Rojesh, Wang, Luqiang, Yu, Wei, Holdreith, Nicholas, Huang, Xiaobin, Zhang, Yejia, Tong, Wei, Gong, Yanqing, Ahn, Jaimo, Susztak, Katalin, Dyment, Nathanial, Li, Mingyao, Long, Fanxin, Chen, Chider, Seale, Patrick, Qin, Ling

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Contact of myeloma cells induces a characteristic transcriptome signature in skeletal precursor cells – Implications for myeloma bone disease von Julia, Dotterweich, Katrin, Schlegelmilch, Alexander, Keller, Beate, Geyer, Doris, Schneider, Sabine, Zeck, Tower Robert, J, Regina, Ebert, Franz, Jakob, MD, Norbert, Schütze

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Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling von Böhm, Anna-Marei, Dirckx, Naomi, Tower, Robert J., Peredo, Nicolas, Vanuytven, Sebastiaan, Theunis, Koen, Nefyodova, Elena, Cardoen, Ruben, Lindner, Volkhard, Voet, Thierry, Van Hul, Matthias, Maes, Christa

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NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma von Lee, Seungyong, Hwang, Charles, Marini, Simone, Tower, Robert J., Qin, Qizhi, Negri, Stefano, Pagani, Chase A., Sun, Yuxiao, Stepien, David M., Sorkin, Michael, Kubiak, Carrie A., Visser, Noelle D., Meyers, Carolyn A., Wang, Yiyun, Rasheed, Husain A., Xu, Jiajia, Miller, Sarah, Huber, Amanda K., Minichiello, Liliana, Cederna, Paul S., Kemp, Stephen W. P., Clemens, Thomas L., James, Aaron W., Levi, Benjamin

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Glutaminolysis provides nucleotides and amino acids to regulate osteoclast differentiation in mice von Hu, Guoli, Yu, Yilin, Ren, Yinshi, Tower, Robert J, Zhang, Guo-Fang, Karner, Courtney M

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Periarticular Mesenchymal Progenitors Initiate and Contribute to Secondary Ossification Center Formation During Mouse Long Bone Development von Tong, Wei, Tower, Robert J., Chen, Chider, Wang, Luqiang, Zhong, Leilei, Wei, Yulong, Sun, Hao, Cao, Gaoyuan, Jia, Haoruo, Pacifici, Maurizio, Koyama, Eiki, Enomoto‐Iwamoto, Motomi, Qin, Ling

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Neutrophil and NETosis Modulation in Traumatic Heterotopic Ossification von Nunez, Johanna H., Juan, Conan, Sun, Yuxiao, Hong, Jonathan, Bancroft, Alec C., Hwang, Charles, Medrano, Jessica, Huber, Amanda K., Tower, Robert J, Levi, Benjamin

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Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism von Dirckx, Naomi, Tower, Robert J, Mercken, Evi M, Vangoitsenhoven, Roman, Moreau-Triby, Caroline, Breugelmans, Tom, Nefyodova, Elena, Cardoen, Ruben, Mathieu, Chantal, Van der Schueren, Bart, Confavreux, Cyrille B, Clemens, Thomas L, Maes, Christa

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Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling von Tower, Robert J., Li, Zhu, Cheng, Yu-Hao, Wang, Xue-Wei, Rajbhandari, Labchan, Zhang, Qian, Negri, Stefano, Uytingco, Cedric R., Venkatesan, Arun, Zhou, Feng-Quan, Cahan, Patrick, James, Aaron W., Clemens, Thomas L.

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NELL1 Regulates the Matrisome to Promote Osteosarcoma Progression von Qin, Qizhi, Gomez-Salazar, Mario, Tower, Robert J, Chang, Leslie, Morris, Carol D, McCarthy, Edward F, Ting, Kang, Zhang, Xinli, James, Aaron W

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Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration von Tower, Robert J, Busse, Emily, Jaramillo, Josue, Lacey, Michelle, Hoffseth, Kevin, Guntur, Anyonya R, Simkin, Jennifer, Sammarco, Mimi C

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Macrophage-mediated PDGF Activation Correlates With Regenerative Outcomes Following Musculoskeletal Trauma von Chowdary, Ashish R., Maerz, Tristan, Henn, Dominic, Hankenson, Kurt D., Pagani, Chase A., Marini, Simone, Gallagher, Katherine, Aguilar, Carlos A., Tower, Robert J., Levi, Benjamin

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Periosteal Mesenchymal Progenitor Dysfunction and Extraskeletally‐Derived Fibrosis Contribute to Atrophic Fracture Nonunion von Wang, Luqiang, Tower, Robert J, Chandra, Abhishek, Yao, Lutian, Tong, Wei, Xiong, Zekang, Tang, Kai, Zhang, Yejia, Liu, X Sherry, Boerckel, Joel D, Guo, Xiaodong, Ahn, Jaimo, Qin, Ling

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The KISS1 Receptor as an In Vivo Microenvironment Imaging Biomarker of Multiple Myeloma Bone Disease von Dotterweich, Julia, Tower, Robert J, Brandl, Andreas, Müller, Marc, Hofbauer, Lorenz C, Beilhack, Andreas, Ebert, Regina, Glüer, Claus C, Tiwari, Sanjay, Schütze, Norbert, Jakob, Franz

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Nr4a1 enhances Wnt4 transcription to promote mesenchymal stem cell osteogenesis and alleviates inflammation-inhibited bone regeneration von Gao, Yangshuai, Zou, Yuming, Sokolowskei, Dimitri, Xing, Xin, Tower, Robert J., Lai, Zejia, Shi, Jiawei, Zhu, Liheng, Zheng, Quan, James, Aaron W., Xu, Jiajia, Zhang, Zhongmin

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NGF-p75 signaling coordinates skeletal cell migration during bone repair von Xu, Jiajia, Li, Zhao, Tower, Robert J, Negri, Stefano, Wang, Yiyun, Meyers, Carolyn A, Sono, Takashi, Qin, Qizhi, Lu, Amy, Xing, Xin, McCarthy, Edward F, Clemens, Thomas L, James, Aaron W

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Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells von Wang, Yiyun, Thottappillil, Neelima, Gomez-Salazar, Mario, Tower, Robert J., Qin, Qizhi, Del Rosario Alvia, Ishbel Camila, Xu, Mingxin, Cherief, Masnsen, Cheng, Ray, Archer, Mary, Arondekar, Shreya, Reddy, Sashank, Broderick, Kristen, Péault, Bruno, James, Aaron W.

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The Mohawk homeobox gene represents a marker and osteo-inhibitory factor in calvarial suture osteoprogenitor cells von Wang, Yiyun, Qin, Qizhi, Wang, Ziyi, Negri, Stefano, Sono, Takashi, Tower, Robert J., Li, Zhao, Xing, Xin, Archer, Mary, Thottappillil, Neelima, Zhu, Manyu, Suarez, Allister, Kim, Deok-Ho, Harvey, Tyler, Fan, Chen-Ming, James, Aaron W.

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A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth von Dirckx, Naomi, Zhang, Qian, Chu, Emily Y, Tower, Robert J, Li, Zhu, Guo, Shenghao, Yuan, Shichen, Khare, Pratik A, Zhang, Cissy, Verardo, Angela, Alejandro, Lucy O, Park, Angelina, Faugere, Marie-Claude, Helfand, Stephen L, Somerman, Martha J, Riddle, Ryan C, de Cabo, Rafael, Le, Anne, Schmidt-Rohr, Klaus, Clemens, Thomas L

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