Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes von Zambetti, Noemi A, Bindels, Eric M J, Van Strien, Paulina M H, Valkhof, Marijke G, Adisty, Maria N, Hoogenboezem, Remco M, Sanders, Mathijs A, Rommens, Johanna M, Touw, Ivo P, Raaijmakers, Marc H G P

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MicroRNA-155 induces AML in combination with the loss of C/EBPA in mice von Alemdehy, M F, de Looper, H W J, Kavelaars, F G, Sanders, M A, Hoogenboezem, R, Löwenberg, B, Valk, P J M, Touw, I P, Erkeland, S J

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Mutations in the Gene for the Granulocyte Colony-Stimulating–Factor Receptor in Patients with Acute Myeloid Leukemia Preceded by Severe Congenital Neutropenia von Dong, Fan, Brynes, Russell K, Tidow, Nicola, Welte, Karl, Löwenberg, Bob, Touw, Ivo P

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Regulation of granulopoiesis by transcription factors and cytokine signals von WARD, A. C, LOEB, D. M, SOEDE-BOBOK, A. A, TOUW, I. P, FRIEDMAN, A. D

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Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation sign... von Erkeland, S J, Aarts, L H, Irandoust, M, Roovers, O, Klomp, A, Valkhof, M, Gits, J, Eyckerman, S, Tavernier, J, Touw, I P

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Hematopoietic Growth Factors and Their Receptors in Acute Leukemia von Löwenberg, Bob, Touw, Ivo P.

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Hematopoietic stem cell transplantation in severe congenital neutropenia von Carlsson, G., Winiarski, J., Ljungman, P., Ringdén, O., Mattsson, J., Nordenskjöld, M., Touw, I., Henter, J.-I., Palmblad, J., Fadeel, B., Hägglund, H.

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Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia von WARD, A. C, VAN AESCH, Y. M, SCHELEN, A. M, TOUW, I. P

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Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors von GITS, J, VAN LEEUWEN, D, CARROLL, H. P, TOUW, I. P, WARD, A. C

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The Carboxyl Terminus of the Granulocyte Colony- Stimulating Factor Receptor, Truncated in Patients with Severe Congenital Neutropenia/Acute Myeloid Leukemia, Is Required for SH2-C... von Dong, Fan, Qiu, Yaling, Yi, Taolin, Touw, Ivo P, Larner, Andrew C

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Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation von FAN DONG, VAN BUITTENEN, C, POUWELS, K, HOEFSLOOT, L. H, LÖWENBERG, B, TOUW, I. P

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Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia von DONG, F, DALE, D. C, WELTE, K, LÖWENBERG, B, TOUW, I. P, BONILLA, M. A, FREEDMAN, M, FASTH, A, NEIJENS, H. J, PALMBLAD, J, BRIARS, G. L, CARLSSON, G, VEERMAN, A. J. P

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Perturbed granulopoiesis in mice with a targeted mutation in the granulocyte colony-stimulating factor receptor gene associated with severe chronic neutropenia von HERMANS, M. H. A, WARD, A. C, ANTONISSEN, C, KARIS, A, LÖWENBERG, B, TOUW, I. P

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C/EBPα and G-CSF receptor signals cooperate to induce the myeloperoxidase and neutrophil elastase genes von WANG, W, WANG, X, WARD, A. C, TOUW, I. P, FRIEDMAN, A. D

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Acute lymphoblastic leukemia in a patient with congenital neutropenia without G-CSF-R and ELA2 mutations von Yetgin, S, Germeshausen, M, Touw, I, Koç, A, Olcay, L

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Identification of a Nonsense Mutation in the Granulocyte-Colony-Stimulating Factor Receptor in Severe Congenital Neutropenia von Dong, Fan, Hoefsloot, Lies H., Schelen, Anita M., Lianne C. A. M. Broeders, Meijer, Yolande, Anjo J. P. Veerman, Touw, Ivo P., Lowenberg, Bob

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Severe congenital neutropenia and chronic neutrophilic leukemia: an intriguing molecular connection unveiled by oncogenic mutations in CSF3R von Touw, Ivo P, Beekman, Renée

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Multiple Signals Mediate Proliferation, Differentiation, and Survival from the Granulocyte Colony-stimulating Factor Receptor in Myeloid 32D Cells von Ward, Alister C., Smith, Louise, de Koning, John P., van Aesch, Yvette, Touw, Ivo P.

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The SH2 domain-containing protein tyrosine phosphatase SHP-1 is induced by granulocyte colony-stimulating factor (G-CSF) and modulates signaling from the G-CSF receptor von WARD, A. C, OOMEN, S. P. M. A, SMITH, L, GITS, J, VAN LEEUWEN, D, SOEDE-BOBOK, A. A, ERPELINCK-VERSCHUEREN, C. A. J, YI, T, TOUW, I. P

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Autonomous Proliferation of Leukemic Cells in Vitro as a Determinant of Prognosis in Adult Acute Myeloid Leukemia von Lowenberg, Bob, van Putten, Wim, Touw, Ivo P, Delwel, Ruud, Santini, Valeria

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