T-Cell Dependent Immunogenicity of Protein Therapeutics Pre-clinical Assessment and Mitigation-Updated Consensus and Review 2020 von Jawa, Vibha, Terry, Frances, Gokemeijer, Jochem, Mitra-Kaushik, Shibani, Roberts, Brian J, Tourdot, Sophie, De Groot, Anne S

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Editorial: Induction of immune tolerance: addressing unmet medical need in immune mediated diseases and immune responses to biologics von Rosenberg, Amy S., Tourdot, Sophie, Markusic, David

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Assay format diversity in pre-clinical immunogenicity risk assessment: Toward a possible harmonization of antigenicity assays von Ducret, Axel, Ackaert, Chloé, Bessa, Juliana, Bunce, Campbell, Hickling, Timothy, Jawa, Vibha, Kroenke, Mark A., Lamberth, Kasper, Manin, Anaïs, Penny, Hweixian L., Smith, Noel, Terszowski, Grzegorz, Tourdot, Sophie, Spindeldreher, Sebastian

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Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals von Tourdot, Sophie, Baltrunkonis, Daniel, Denies, Sofie, Devanarayan, Viswanath, Grudzinska-Goebel, Joanna, Kromminga, Arno, Lotz, Gregor P, Malherbe, Laurent, Michaut, Lydia, Weldingh, Karin N, Pedras-Vasconcelos, Joao A, Salazar-Fontana, Laura I, Spindeldreher, Sebastian, Sauna, Zuben, Snoeck, Veerle, Verthelyi, Daniela, Kramer, Daniel

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HLAII peptide presentation of infliximab increases when complexed with TNF von Casasola-LaMacchia, Andrea, Seward, Robert Joseph, Tourdot, Sophie, Willetts, Matthew, Kruppa, Gary, Agostino, Michael J, Bergeron, Gabrielle, Ahyi-Amendah, Nathalie, Ciarla, Andrew, Lu, Zhaojiang, Kim, Hai-Young, Hickling, Timothy P, Neubert, Hendrik

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Efficacy of sublingual vectorized recombinant Bet v 1a in a mouse model of birch pollen allergic asthma von Tourdot, Sophie, Airouche, Sabi, Berjont, Nathalie, Moussu, Hélène, Betbeder, Didier, Nony, Emmanuel, Bordas-Le Floch, Véronique, Baron-Bodo, Véronique, Mascarell, Laurent, Moingeon, Philippe

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Bifidobacterium bifidum NCC 453 Promotes Tolerance Induction in Murine Models of Sublingual Immunotherapy von Moussu, Hélène, Van Overtvelt, Laurence, Horiot, Stéphane, Tourdot, Sophie, Airouche, Sabi, Zuercher, Adrian, Holvoet, Sébastien, Prioult, Guénolée, Nutten, Sophie, Mercenier, Annick, Mascarell, Laurent, Moingeon, Philippe

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A general strategy to enhance immunogenicity of low‐affinity HLA‐A2.1‐associated peptides: implication in the identification of cryptic tumor epitopes von Tourdot, Sophie, Scardino, Antonio, Saloustrou, Eleanna, Gross, David A., Pascolo, Steve, Cordopatis, Pavlos, Lemonnier, François A., Kosmatopoulos, Kostas

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Nonclinical immunogenicity risk assessment of therapeutic proteins von Tourdot, Sophie, Hickling, Timothy P

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H‐2 class I knockout, HLA‐A2.1‐transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies von Firat, Hüseyin, Garcia‐Pons, Francisco, Tourdot, Sophie, Pascolo, Steve, Scardino, Antonio, Garcia, Zacarias, Michel, Marie‐Louise, Jack, Ralph Wiliams, Jung, Günther, Kosmatopoulos, Konstadinos, Mateo, Luis, Suhrbier, Andreas, Lemonnier, François A., Langlade‐Demoyen, Pierre

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An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR‐T and TCR‐T Cellular Therapies Development von Gokemeijer, Jochem, Balasubramanian, Nanda, Ogasawara, Ken, Grudzinska‐Goebel, Joanna, Upreti, Vijay V., Mody, Hardik, Kasar, Siddha, Vepachedu, Venkata R., Xu, Weifeng, Gupta, Swati, Tarcsa, Edit, Dodge, Robert, Herr, Kate, Yang, Tong‐Yuan, Tourdot, Sophie, Jawa, Vibha

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Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium von Hässler, Signe, Bachelet, Delphine, Duhaze, Julianne, Szely, Natacha, Gleizes, Aude, Hacein-Bey Abina, Salima, Aktas, Orhan, Auer, Michael, Avouac, Jerôme, Birchler, Mary, Bouhnik, Yoram, Brocq, Olivier, Buck-Martin, Dorothea, Cadiot, Guillaume, Carbonnel, Franck, Chowers, Yehuda, Comabella, Manuel, Derfuss, Tobias, De Vries, Niek, Donnellan, Naoimh, Doukani, Abiba, Guger, Michael, Hartung, Hans-Peter, Kubala Havrdova, Eva, Hemmer, Bernhard, Huizinga, Tom, Ingenhoven, Kathleen, Hyldgaard-Jensen, Poul Erik, Jury, Elizabeth C, Khalil, Michael, Kieseier, Bernd, Laurén, Anna, Lindberg, Raija, Loercher, Amy, Maggi, Enrico, Manson, Jessica, Mauri, Claudia, Mohand Oumoussa, Badreddine, Montalban, Xavier, Nachury, Maria, Nytrova, Petra, Richez, Christophe, Ryner, Malin, Sellebjerg, Finn, Sievers, Claudia, Sikkema, Dan, Soubrier, Martin, Tourdot, Sophie, Trang, Caroline, Vultaggio, Alessandra, Warnke, Clemens, Spindeldreher, Sebastian, Dönnes, Pierre, Hickling, Timothy P, Hincelin Mery, Agnès, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe

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Development and application of an in vitro dendritic cell internalization assay to assess immunogenicity risk von Halimani, Mahantappa, Atkuri, Kondala, Goiberg, Polina, You, Zhiping, Steeno, Greg, Tourdot, Sophie, Xue, Li, Lepsy, Chris, Hickling, Tim, King, Lindsay

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Survey Outcome on Immunogenicity Risk Assessment Tools for Biotherapeutics: an Insight into Consensus on Methods, Application, and Utility in Drug Development von Gokemeijer, Jochem, Wen, Yi, Jawa, Vibha, Mitra-Kaushik, Shibani, Chung, Shan, Goggins, Alan, Kumar, Seema, Lamberth, Kasper, Liao, Karen, Lill, Jennie, Phung, Qui, Walsh, Robin, Roberts, Brian J., Swanson, Michael, Singh, Inderpal, Tourdot, Sophie, Kroenke, Mark A., Rup, Bonita, Goletz, Theresa J., Gupta, Swati, Malherbe, Laurent, Pattijn, Sofie

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Identification of HER‐2/neu immunogenic epitopes presented by renal cell carcinoma and other human epithelial tumors von Scardino, Antonio, Alves, Pedro, Gross, David A., Tourdot, Sophie, Graff‐Dubois, Stephanie, Angevin, Eric, Firat, Hüseyin, Chouaib, Salem, Lemonnier, François, Nadler, Lee M., Cardoso, Angelo A., Kosmatopoulos, Kostas

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Quantitative analysis of the CD4+ T cell response to therapeutic antibodies in healthy donors using a novel T cell:PBMC assay von Schultz, Heidi S, Reedtz-Runge, Stine Louise, Bäckström, B Thomas, Lamberth, Kasper, Pedersen, Christian R, Kvarnhammar, Anne M

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Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A von Bachelet, Delphine, Albert, Thilo, Mbogning, Cyprien, Hässler, Signe, Zhang, Yuan, Schultze-Strasser, Stephan, Repessé, Yohann, Rayes, Julie, Pavlova, Anna, Pezeshkpoor, Behnaz, Liphardt, Kerstin, Davidson, Julie E, Hincelin-Méry, Agnès, Dönnes, Pierre, Lacroix-Desmazes, Sébastien, Königs, Christoph, Oldenburg, Johannes, Broët, Philippe

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European Immunogenicity Platform 11th Open Scientific Symposium on immunogenicity of biopharmaceuticals von Tourdot, Sophie, Quaglia, Carolina B, Chamberlain, Paul, De Groot, Anne S, Dellas, Nikki, Guillemare, Eric, Kromminga, Arno, Lotz, Gregor P, Mingozzi, Federico, Piccoli, Luca, Pine, Samuel, Richards, Susan, Waxenecker, Günter, Kramer, Daniel

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A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins von Kierzek, Andrzej M., Hickling, Timothy P., Figueroa, Isabel, Kalvass, J. Cory, Nijsen, Marjoleen, Mohan, Krithika, Veldman, Geertruida M., Yamada, Akihiro, Sayama, Hiroyuki, Yokoo, Sachiko, Gulati, Abhishek, Dhanikula, Renu S., Gokemeijer, Jochem, Leil, Tarek A., Thalhauser, Craig J., Giorgi, Mario, Swat, Maciej J., Chelliah, Vijayalakshmi, Small, Ben G., Benson, Neil, Walker, Michael, Gadkar, Kapil, Quarmby, Valerie, Deng, Rong, Ferrante, Andrea, Dickinson, Gemma L., Van Der Walt, Jan‐Stefan, Zhou, Lian, Chen, Xiaoying, Jones, Hannah M., Narula, Jatin, Tourdot, Sophie, Lavé, Thierry, Ribba, Benjamin, Graaf, Piet H.

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Expression and Characterization of Natural-Like Recombinant Der p 2 for Sublingual Immunotherapy von Bordas-Le Floch, Véronique, Bussières, Laetitia, Airouche, Sabi, Lautrette, Aurélie, Bouley, Julien, Berjont, Nathalie, Horiot, Stéphane, Huet, Axelle, Jain, Karine, Lemoine, Pierrick, Chabre, Henri, Batard, Thierry, Mascarell, Laurent, Baron-Bodo, Véronique, Tourdot, Sophie, Nony, Emmanuel, Moingeon, Philippe

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