Complete Inhibition of Anisomycin and UV Radiation but Not Cytokine Induced JNK and p38 Activation by an Aryl-substituted Dihydropyrrolopyrazole Quinoline and Mixed Lineage Kinase... von Wang, Xushan, Mader, Mary M., Toth, John E., Yu, Xiaohong, Jin, Najia, Campbell, Robert M., Smallwood, Jeffrey K., Christe, Michael E., Chatterjee, Arindam, Goodson, Theodore, Vlahos, Chris J., Matter, William F., Bloem, Laura J.

Volltext

Imidazolyl benzimidazoles and imidazo[4,5- b]pyridines as potent p38α MAP kinase inhibitors with excellent in vivo antiinflammatory properties von Mader, Mary, de Dios, Alfonso, Shih, Chuan, Bonjouklian, Rosanne, Li, Tiechao, White, Wesley, de Uralde, Beatriz López, Sánchez-Martinez, Concepción, del Prado, Miriam, Jaramillo, Carlos, de Diego, Eugenio, Martín Cabrejas, Luisa M., Dominguez, Carmen, Montero, Carlos, Shepherd, Timothy, Dally, Robert, Toth, John E., Chatterjee, Arindam, Pleite, Sehila, Blanco-Urgoiti, Jaime, Perez, Leticia, Barberis, Mario, Lorite, María José, Jambrina, Enrique, Nevill, C. Richard, Lee, Paul A., Schultz, Richard C., Wolos, Jeffrey A., Li, Li C., Campbell, Robert M., Anderson, Bryan D.

Volltext

Studies on the Mechanism of Phosphatidylinositol 3-Kinase Inhibition by Wortmannin and Related Analogs von Norman, Bryan H, Shih, Chuan, Toth, John E, Ray, James E, Dodge, Jeffrey A, Johnson, Doug W, Rutherford, Pamela G, Schultz, Richard M, Worzalla, John F, Vlahos, Chris J

Volltext

Synthesis and In Vitro Antimicrobial Activity of 3-Keto 16-Membered Macrolides Derived From Tylosin von CREEMER, LAWRENCE C., TOTH, JOHN E., KIRST, HERBERT A.

Volltext

Structures of Three Inhibitor Complexes Provide Insight into the Reaction Mechanism of the Human Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase von Schmidt, Andrea, Wu, Haiping, MacKenzie, Robert E, Chen, Victor J, Bewly, Jesse R, Ray, James E, Toth, John E, Cygler, Miroslaw

Volltext

Synthesis and resolution of sulfonimidamide analogs of sulfonylureas von Toth, John E, Ray, James, Deeter, Jack

Volltext

A concise synthesis of quinazolinone TGF-β RI inhibitor through one-pot three-component Suzuki–Miyaura/etherification and imidate–amide rearrangement reactions von Li, Hong-yu, Wang, Yan, McMillen, William T., Chatterjee, Arindam, Toth, John E., Mundla, Sreenivasa R., Voss, Matthew, Boyer, Robert D., Sawyer, J. Scott

Volltext

Sulfonimidamide analogs of oncolytic sulfonylureas von TOTH, J. E, GRINDEY, G. B, WEIR, L. C, WORZALLA, J. F, EHLHARDT, W. J, RAY, J. E, BODER, G. B, BEWLEY, J. R, KLINGERMAN, K. K, GATES, S. B, RINZEL, S. M, SCHULTZ, R. M

Volltext

Sulfonimidamide Analogs of Oncolytic Sulfonylureas † ,1 von Toth, John E, Grindey, Gerald B, Ehlhardt, William J, Ray, James E, Boder, George B, Bewley, Jesse R, Klingerman, Kim K, Gates, Susan B, Rinzel, Sharon M, Schultz, Richard M, Weir, Leonard C, Worzalla, John F

Volltext

Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas von Ehlhardt, William J, Woodland, Joseph M, Worzalla, John F, Bewley, Jesse R, Grindey, Gerald B, Todd, Glen C, Toth, John E, Howbert, J. Jeffry

Volltext

Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics von Kirst, Herbert A, Toth, John E, Debono, Manuel, Willard, Kevin E, Truedell, Brenda A, Ott, John L, Counter, Fred T, Felty-Duckworth, Anna M, Pekarek, Robert S

Volltext

Diamino Benzo[b]thiophene Derivatives as a Novel Class of Active Site Directed Thrombin Inhibitors. 5. Potency, Efficacy, and Pharmacokinetic Properties of Modified C-3 Side Chain... von Sall, Daniel J, Bailey, Dianna L, Bastian, Jolie A, Buben, John A, Chirgadze, Nickolay Y, Clemens-Smith, Amy C, Denney, Michael L, Fisher, Matthew J, Giera, Deborah D, Gifford-Moore, Donetta S, Harper, Richard W, Johnson, Lea M, Klimkowski, Valentine J, Kohn, Todd J, Lin, Ho-Shen, McCowan, Jefferson R, Palkowitz, Alan D, Richett, Michael E, Smith, Gerald F, Snyder, David W, Takeuchi, Kumiko, Toth, John E, Zhang, Minsheng

Volltext

Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region) von Varie, David L., Shih, Chuan, Hay, David A., Andis, Sherri L., Corbett, Tom H., Gossett, Lynn S., Janisse, Samantha K., Martinelli, Michael J., Moher, Eric D., Schultz, Richard M., Toth, John E.

Volltext

Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli von Allen, Norris E, Alborn, William E, Kirst, Herbert A, Toth, John E

Volltext

Control of site-specific substitution of aminoglycosides by transition metal cations von Kirst, Herbert A., Truedell, Brenda A., Toth, John E.

Volltext

Effects of diarylsulfonylurea antitumor agents on the function of mitochondria isolated from rat liver and GC3/c1 cells von Rush, Glenn F., Rinzel, Sharon, Boder, George, Alan Heim, R., Toth, John E., Doug Ponsler, G.

Volltext

2,3-Dihydroxy-9-amino-9,10-dihydrophenanthrene, a rigid congener of dopamine and isoapomorphine von Nichols, David E, Toth, John E, Kohli, Jai D, Kotake, Connie K

Volltext

Imidazolyl benzimidazoles and imidazo[4,5-b]pyridines as potent p38alpha MAP kinase inhibitors with excellent in vivo antiinflammatory properties von Mader, Mary, de Dios, Alfonso, Shih, Chuan, Bonjouklian, Rosanne, Li, Tiechao, White, Wesley, López de Uralde, Beatriz, Sánchez-Martinez, Concepción, del Prado, Miriam, Jaramillo, Carlos, de Diego, Eugenio, Martín Cabrejas, Luisa M, Dominguez, Carmen, Montero, Carlos, Shepherd, Timothy, Dally, Robert, Toth, John E, Chatterjee, Arindam, Pleite, Sehila, Blanco-Urgoiti, Jaime, Perez, Leticia, Barberis, Mario, Lorite, María José, Jambrina, Enrique, Nevill, Jr, C Richard, Lee, Paul A, Schultz, Richard C, Wolos, Jeffrey A, Li, Li C, Campbell, Robert M, Anderson, Bryan D

Volltext

The synthesis of o-aminophenyl sulfate metabolites of the oncolytic sulfonylureas von Toth, John E., Ray, James, Ehihardt, William J.

Volltext

Synthesis and in vitro Antimicrobial Activity of 3-Keto 16-Membered Macrolides Derived from Tylosin von Creemer, Lawrence C., Toth, John E., Kirst, Herbert A.

Volltext