Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies von Rocamora, Frances, Peralta, Angelo G., Shin, Seunghyeon, Sorrentino, James, Wu, Mina Ying Min, Toth, Eric A., Fuerst, Thomas R., Lewis, Nathan E.

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Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies von Metcalf, Matthew C., Janus, Benjamin M., Yin, Rui, Wang, Ruixue, Guest, Johnathan D., Pozharski, Edwin, Law, Mansun, Mariuzza, Roy A., Toth, Eric A., Pierce, Brian G., Fuerst, Thomas R., Ofek, Gilad

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Prospects for developing an Hepatitis C virus E1E2-based nanoparticle vaccine von Toth, Eric A, Andrianov, Alexander K, Fuerst, Thomas R

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Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development von Pierce, Brian G, Felbinger, Nathaniel, Metcalf, Matthew, Toth, Eric A, Ofek, Gilad, Fuerst, Thomas R

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Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge von Romanyuk, Andrey, Wang, Ruixue, Marin, Alexander, Janus, Benjamin M, Felner, Eric I, Xia, Dengning, Goez-Gazi, Yenny, Alfson, Kendra J, Yunus, Abdul S, Toth, Eric A, Ofek, Gilad, Carrion, Jr, Ricardo, Prausnitz, Mark R, Fuerst, Thomas R, Andrianov, Alexander K

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Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development von Toth, Eric A., Chagas, Andrezza, Pierce, Brian G., Fuerst, Thomas R.

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Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein von Li, Xiaofeng, Kulakova, Liudmila, Jones, Kezzia, Toth, Eric A., Mitchell, Marina Kirkland, Mendez, Qiana, Weiner, Michael P., Fuerst, Thomas R.

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Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization von Pierce, Brian G., Keck, Zhen-Yong, Wang, Ruixue, Lau, Patrick, Garagusi, Kyle, Elkholy, Khadija, Toth, Eric A., Urbanowicz, Richard A., Guest, Johnathan D., Agnihotri, Pragati, Kerzic, Melissa C., Marin, Alexander, Andrianov, Alexander K., Ball, Jonathan K., Mariuzza, Roy A., Fuerst, Thomas R., Foung, Steven K. H.

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Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate von Wang, Ruixue, Suzuki, Saori, Guest, Johnathan D, Heller, Brigitte, Almeda, Maricar, Andrianov, Alexander K, Marin, Alexander, Mariuzza, Roy A, Keck, Zhen-Yong, Foung, Steven K H, Yunus, Abdul S, Pierce, Brian G, Toth, Eric A, Ploss, Alexander, Fuerst, Thomas R

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Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor von Manvilla, Brittney A., Pozharski, Edwin, Toth, Eric A., Drohat, Alexander C.

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Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer von Guest, Johnathan D., Wang, Ruixue, Elkholy, Khadija H., Chagas, Andrezza, Chao, Kinlin L., Cleveland, Thomas E., Kim, Young Chang, Keck, Zhen-Yong, Marin, Alexander, Yunus, Abdul S., Mariuzza, Roy A., Andrianov, Alexander K., Toth, Eric A., Foung, Steven K. H., Pierce, Brian G., Fuerst, Thomas R.

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Hsp70 Is a Novel Posttranscriptional Regulator of Gene Expression That Binds and Stabilizes Selected mRNAs Containing AU-Rich Elements von Kishor, Aparna, Tandukar, Bishal, Ly, Yann V., Toth, Eric A., Suarez, Yvelisse, Brewer, Gary, Wilson, Gerald M.

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Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA von Manvilla, Brittney A., Maiti, Atanu, Begley, Matthew C., Toth, Eric A., Drohat, Alexander C.

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A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization von Erzurumlu, Yalcin, Aydin Kose, Fadime, Gozen, Oguz, Gozuacik, Devrim, Toth, Eric A., Ballar, Petek

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Alternatively Expressed Domains of AU-rich Element RNA-binding Protein 1 (AUF1) Regulate RNA-binding Affinity, RNA-induced Protein Oligomerization, and the Local Conformation of Bo... von Zucconi, Beth E., Ballin, Jeff D., Brewer, Brandy Y., Ross, Christina R., Huang, Jun, Toth, Eric A., Wilson, Gerald M.

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Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein von Lanning, Maryanna E., Yu, Wenbo, Yap, Jeremy L., Chauhan, Jay, Chen, Lijia, Whiting, Ellis, Pidugu, Lakshmi S., Atkinson, Tyler, Bailey, Hala, Li, Willy, Roth, Braden M., Hynicka, Lauren, Chesko, Kirsty, Toth, Eric A., Shapiro, Paul, MacKerell, Alexander D., Wilder, Paul T., Fletcher, Steven

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A Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex Interactions von Luncsford, Paz J., Chang, Dau-Yin, Shi, Guoli, Bernstein, Jade, Madabushi, Amrita, Patterson, Dimeka N., Lu, A-Lien, Toth, Eric A.

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Metal-Assisted and Microwave-Accelerated Evaporative Crystallization: Proof-of-Principle Application to Proteins von Mauge-Lewis, Kevin, Mojibola, Adeolu, Toth, Eric A, Mohammed, Muzaffer, Seifu, Dereje, Aslan, Kadir

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The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid von Malik, Shuja S., Patterson, Dimeka N., Ncube, Ziphezinhle, Toth, Eric A.

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Covalent Small Molecule Inhibitors of Ca2+-Bound S100B von Cavalier, Michael C, Pierce, Adam D, Wilder, Paul T, Alasady, Milad J, Hartman, Kira G, Neau, David B, Foley, Timothy L, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Toth, Eric A, Weber, David J

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