HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma von Courtney, Kevin D., Ma, Yuanqing, de Leon, Alberto Diaz, Christie, Alana, Xie, Zhiqun, Woolford, Layton, Singla, Nirmish, Joyce, Allison, Hill, Haley, Madhuranthakam, Ananth J., Yuan, Qing, Xi, Yin, Zhang, Yue, Chang, Jenny, Fatunde, Oluwatomilade, Arriaga, Yull, Frankel, Arthur E., Kalva, Sanjeeva, Zhang, Song, McKenzie, Tiffani, Torras, Oscar Reig, Figlin, Robert A., Rini, Brian, McKay, Renee M., Kapur, Payal, Wang, Tao, Pedrosa, Ivan, Brugarolas, James

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Molecular Genetic Determinants of Shorter Time on Active Surveillance in a Prospective Phase 2 Clinical Trial in Metastatic Renal Cell Carcinoma von Reig Torras, Oscar, Mishra, Akhilesh, Christie, Alana, McKenzie, Tiffani, Onabolu, Oreoluwa, Singla, Nirmish, Plimack, Elizabeth R., Suárez, Cristina, Ornstein, Moshe C., Alpaugh, R. Katherine, Elias, Roy, Bowman, I. Alex, McKay, Renee M., Przybycin, Christopher, Kapur, Payal, Brugarolas, James, Rini, Brian

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Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis von Prakasam, Gopinath, Mishra, Akhilesh, Christie, Alana, Miyata, Jeffrey, Carrillo, Deyssy, Tcheuyap, Vanina T, Ye, Hui, Do, Quyen N, Wang, Yunguan, Reig Torras, Oscar, Butti, Ramesh, Zhong, Hua, Gagan, Jeffrey, Jones, Kevin B, Carroll, Thomas J, Modrusan, Zora, Durinck, Steffen, Requena-Komuro, Mai-Carmen, Williams, Noelle S, Pedrosa, Ivan, Wang, Tao, Rakheja, Dinesh, Kapur, Payal, Brugarolas, James

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A renal cell carcinoma tumorgraft platform to advance precision medicine von Elias, Roy, Tcheuyap, Vanina T., Kaushik, Akash K., Singla, Nirmish, Gao, Ming, Reig Torras, Oscar, Christie, Alana, Mulgaonkar, Aditi, Woolford, Layton, Stevens, Christina, Kettimuthu, Kavitha Priya, Pavia-Jimenez, Andrea, Boroughs, Lindsey K., Joyce, Allison, Dakanali, Marianna, Notgrass, Hollis, Margulis, Vitaly, Cadeddu, Jeffrey A., Pedrosa, Ivan, Williams, Noelle S., Sun, Xiankai, DeBerardinis, Ralph J., Öz, Orhan K., Zhong, Hua, Seshagiri, Somasekar, Modrusan, Zora, Cantarel, Brandi L., Kapur, Payal, Brugarolas, James

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SOGUG-vexillum: Phase II non-randomized clinical trial of nivolumab/ipilimumab maintenance following first-line chemotherapy in unresectable locally advanced or metastatic urotheli... von de Velasco, Guillermo, Alvarez-Fernandez, Carlos, Alvarez Marquez, Francisco Jose, Reig Torras, Oscar, Virizuela, Juan Antonio, Anido, Urbano, Azkarate, Aitor, Gajate, Pablo, Garcia Carbonero, Iciar, Iranzo Sabater, Aina, Lozano, Rebeca, Pujol, Eduardo

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Does the time-of-day administration of immune checkpoint inhibitors affect efficacy in patients with metastatic renal cell carcinoma? A single-center study von Fernandez-Mañas, Laia, Gonzalez Aguado, Laura, Aversa, Caterina, Ferrer-Mileo, Laura, Garcia de Herreros, Marta, Jiménez, Natalia, Febrer, Albert, Vernet, Roger, García-Esteve, Samuel, Mellado, Begona, Reig Torras, Oscar

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Development and independent validation of a predictive gene expression signature based on RB1, PTEN, and TP53 in patients with metastatic hormone-sensitive metastatic prostate canc... von Reig Torras, Oscar, Garcia de Herreros, Marta, Jiménez, Natalia, Aversa, Caterina, Marín-Aguilera, Mercedes, Ferrer Mileo, Laura, Rodriguez-Carunchio, Leonardo, Trias, Isabel, Font Pous, Albert, Rodriguez-Vida, Alejo, Domenech-Santasusana, Montserrat, Figols, Mariona, Climent, Miguel Ángel, Cros Costa, Sara, Chirivella, Isabel, Herrero Rivera, Daniel, Jiménez-Peralta, Daniel, Gonzalez -Billalabeitia, Enrique, Carles, Joan, Mellado-Gonzalez, Begoña

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Development and validation of a gene expression signature based on RB1 , PTEN,and TP53 in patients with metastatic hormone-sensitive prostate cancer (mHSPC) von Reig Torras, Oscar, Jiménez, Natalia, Garcia de Herreros, Marta, Aversa, Caterina, Marin, Mercedes, Ferrer, Laura, Rodriguez-Carunchio, Leonardo, Trias, Isabel, Fernandez-Mañas, Laia, García-Esteve, Samuel, Font Pous, Albert, Rodriguez-Vida, Alejo, Domenech-Santasusana, Montserrat, Figols, Mariona, Climent, Miguel Ángel, Cros Costa, Sara, Chirivella, Isabel, Herrero Rivera, Daniel, Suárez, Cristina, Mellado-Gonzalez, Begoña

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INMUNOSUN-SOGUG trial: A prospective phase II study to assess the efficacy and safety of sunitinib as second-line (2L) treatment in patients (pts) with metastatic renal cell cancer... von Grande, Enrique, Alonso Gordoa, Teresa, Reig Torras, Oscar, Esteban, Emilio, Castellano, Daniel, Garcia del Muro, Xavier, Mendez Vidal, María José, García-Donas, Jesús, Arranz, Jose Angel, Suarez Rodriguez, Cristina

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Pancreatic tropism of metastatic renal cell carcinoma von Singla, Nirmish, Xie, Zhiqun, Zhang, Ze, Gao, Ming, Yousuf, Qurratulain, Onabolu, Oreoluwa, McKenzie, Tiffani, Tcheuyap, Vanina Toffessi, Ma, Yuanqing, Choi, Jacob, McKay, Renee, Christie, Alana, Torras, Oscar Reig, Bowman, Isaac A., Margulis, Vitaly, Pedrosa, Ivan, Przybycin, Christopher, Wang, Tao, Kapur, Payal, Rini, Brian, Brugarolas, James

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Prognostic Gene Expression-Based Signature in Clear-Cell Renal Cell Carcinoma von Roldán, Fiorella L, Izquierdo Reyes, Laura, Ingelmo-Torres, Mercedes, Lozano Salvatella, Juan José, Carrasco, Raquel, Cuñado, Alexandra, Reig Torras, Oscar, Mengual Brichs, Lourdes, Alcaraz Asensio, Antonio

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Abstract 785: Molecular profile of sunitinib resistance in clear-cell renal cell carcinoma von Torras, Oscar Reig, Marin-Aguilera, Mercedes, Jiménez, Natalia, Laia, Paré, Galvan, Patricia, Mallofre, Carme, Prat, Aleix, Mellado, Begoña

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Interim analysis of ibrutinib plus paclitaxel for patients with metastatic urothelial carcinoma previously treated with platinum-based chemotherapy von Castellano, Daniel E., Morales-Barrera, Rafael, Duran, Ignacio, Keam, Bhumsuk, Chung, Ik Joo, Arkenau, Tobias, Vaishampayan, Ulka N., Tuthill, Mark, Gajate, Pablo, Shin, Sang Joon, Dang, S. Paul, Ju, Chia-Hsin, Lin, Jennifer, Cole, George, James, Danelle Frances, Reig Torras, Oscar

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Retrospective study to identify clinical factors related to a high benefit of axitinib in mRCC: Results from AXILONG Spanish real-world study von Pinto, Alvaro, Iglesias Gomez, Clara, Climent, Miguel Ángel, Gallardo Diaz, Enrique, Garcia del Muro, Xavier, Alonso Gordoa, Teresa, Llinares Legido, Julia Inmaculada, Suarez Rodriguez, Cristina, Anguera, Georgia, Muñoz-Langa, José, Lainez, Nuria, Rodriguez Sanchez, Angel, Martínez Ortega, Esther, Villalobos, Maria L., Reig Torras, Oscar

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HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor in Clear Cell Renal Cell Carcinoma Patients von Courtney, Kevin D., Ma, Yuanqing, de Leon, Alberto Diaz, Christie, Alana, Xie, Zhiqun, Woolford, Layton, Singla, Nirmish, Joyce, Allison, Hill, Haley, Madhuranthakam, Ananth J., Yuan, Qing, Xi, Yin, Zhang, Yue, Chang, Jenny, Fatunde, Oluwatomilade, Arriaga, Yull, Frankel, Arthur, Kalva, Sanjeeva, Zhang, Song, McKenzie, Tiffani, Torras, Oscar Reig, Figlin, Robert A., Rini, Brian I., McKay, Renée M., Kapur, Payal, Wang, Tao, Pedrosa, Ivan, Brugarolas, James

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DUTRENEO Trial: A phase II randomized trial of DUrvalumab and TREmelimumab as NEOadjuvant approach in muscle-invasive urothelial bladder cancer (MIBC) patients prospectively select... von Grande, Enrique, Guerrero, Félix, Puente, Javier, Galante, Isabel, Duran, Ignacio, Fuentes, Javier, Alonso-Gordoa, Teresa, Burgos, Javier, Font Pous, Albert, Buisan, Oscar, Pinto, Alvaro, Alvarez-Maestro, Mario, Reig Torras, Oscar, Maroto, Pablo, Garcia del Muro, Xavier, Galvan, Patricia, Malats, Nuria, Prat, Aleix, Real, Francisco X., Castellano, Daniel E.

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Transcriptional Profile Associated with Clinical Outcomes in Metastatic Hormone-Sensitive Prostate Cancer Treated with Androgen Deprivation and Docetaxel von Jimenez, Natalia, Reig Torras, Oscar, Marin Aguilera, Mercedes, Aversa, Caterina, Ferrer Mileo, Laura, Font, Albert, Rodriguez Vida, Alejo, Climent, Miguel Ángel, Cros, Sara, Chirivella, Isabel, Domenech, Montserrat, Figols, Mariona, González Billalabeitia, Enrique, Jiménez Peralta, Daniel, Rodriguez Carunchio, Leonardo, Garcia Esteve, Samuel, García de Herrero, Marta, Ribal, Maria J, Prat Aparicio, Aleix, Mellado González, Begoña

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Results from the INMUNOSUN-SOGUG trial: a prospective phase II study of sunitinib as a second-line therapy in patients with metastatic renal cell carcinoma after immune checkpoint-... von Grande, Enrique, Alonso Gordoa, Teresa, Reig Torras, Oscar, Esteban, E, Castellano, D, Garcia Del Muro, Xavier, Mendez, M.J, García Donas, J, González Rodríguez, M, Arranz Arija, José Ángel, Lopez Criado, P, Molina Cerrillo, J, Mellado González, Begoña, Alvarez Fernandez, C, Velasco, G. de, Cuéllar Rivas, M.A, Rodríguez Alonso, R.M, Rodríguez Moreno, J.F, Suarez Rodriguez, C

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Biomarcadors i resistència a la quimioteràpia en càncer de pròstata von Reig Torras, Oscar

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Androgen receptor and its splicing variant 7 expression in peripheral blood mononuclear cells and in circulating tumor cells in metastatic castration-resistant prostate cancer von Marín Aguilera, Mercedes, Jiménez, Natalia, Reig Torras, Oscar, Montalbo Calafell, Ruth, Verma, Ajit K, Castellano, Giancarlo, Mengual Brichs, Lourdes, Victoria, Iván, Pereira, María Verónica, Milà Guasch, Maria, García-Recio, Susana, Benítez-Ribas, Daniel, Cabezón, Raquel, González, Azucena, Juan, Manel, Prat Aparicio, Aleix, Mellado González, Begoña

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