Euhaplorchis californiensis Cercariae Exhibit Positive Phototaxis and Negative Geotaxis von Weinersmith, K. L, Brown, C. E, Clingen, K. B, Jacobsen, M. C, Topper, L. B, Hechinger, R. F

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Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden von Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., Zahnow, Cynthia A.

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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer von Topper, Michael J., Vaz, Michelle, Chiappinelli, Katherine B., DeStefano Shields, Christina E., Niknafs, Noushin, Yen, Ray-Whay Chiu, Wenzel, Alyssa, Hicks, Jessica, Ballew, Matthew, Stone, Meredith, Tran, Phuoc T., Zahnow, Cynthia A., Hellmann, Matthew D., Anagnostou, Valsamo, Strissel, Pamela L., Strick, Reiner, Velculescu, Victor E., Baylin, Stephen B.

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Uncovering sperm metabolome to discover biomarkers for bull fertility von Menezes, E B, Velho, A L C, Santos, F, Dinh, T, Kaya, A, Topper, E, Moura, A A, Memili, E

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Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria von Pejaver, Vikas, Byrne, Alicia B., Feng, Bing-Jian, Pagel, Kymberleigh A., Mooney, Sean D., Karchin, Rachel, O’Donnell-Luria, Anne, Harrison, Steven M., Tavtigian, Sean V., Greenblatt, Marc S., Biesecker, Leslie G., Radivojac, Predrag, Brenner, Steven E., Biesecker, Leslie G., Harrison, Steven M., Tayoun, Ahmad A., Berg, Jonathan S., Brenner, Steven E., Cutting, Garry R., Ellard, Sian, Greenblatt, Marc S., Kang, Peter, Karbassi, Izabela, Karchin, Rachel, Mester, Jessica, O’Donnell-Luria, Anne, Pesaran, Tina, Plon, Sharon E., Rehm, Heidi L., Strande, Natasha T., Tavtigian, Sean V., Topper, Scott

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Epigenetic therapy inhibits metastases by disrupting premetastatic niches von Lu, Zhihao, Zou, Jianling, Li, Shuang, Topper, Michael J., Tao, Yong, Zhang, Hao, Jiao, Xi, Xie, Wenbing, Kong, Xiangqian, Vaz, Michelle, Li, Huili, Cai, Yi, Xia, Limin, Huang, Peng, Rodgers, Kristen, Lee, Beverly, Riemer, Joanne B., Day, Chi-Ping, Yen, Ray-Whay Chiu, Cui, Ying, Wang, Yujiao, Wang, Yanni, Zhang, Weiqiang, Easwaran, Hariharan, Hulbert, Alicia, Kim, KiBem, Juergens, Rosalyn A., Yang, Stephen C., Battafarano, Richard J., Bush, Errol L., Broderick, Stephen R., Cattaneo, Stephen M., Brahmer, Julie R., Rudin, Charles M., Wrangle, John, Mei, Yuping, Kim, Young J., Zhang, Bin, Wang, Ken Kang-Hsin, Forde, Patrick M., Margolick, Joseph B., Nelkin, Barry D., Zahnow, Cynthia A., Pardoll, Drew M., Housseau, Franck, Baylin, Stephen B., Shen, Lin, Brock, Malcolm V.

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Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties von Kong, Xiangqian, Chen, Jie, Xie, Wenbing, Brown, Stephen M., Cai, Yi, Wu, Kaichun, Fan, Daiming, Nie, Yongzhan, Yegnasubramanian, Srinivasan, Tiedemann, Rochelle L., Tao, Yong, Chiu Yen, Ray-Whay, Topper, Michael J., Zahnow, Cynthia A., Easwaran, Hariharan, Rothbart, Scott B., Xia, Limin, Baylin, Stephen B.

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Using the ACMG/AMP framework to capture evidence related to predicted and observed impact on splicing: Recommendations from the ClinGen SVI Splicing Subgroup von Walker, Logan C., Hoya, Miguel de la, Wiggins, George A.R., Lindy, Amanda, Vincent, Lisa M., Parsons, Michael T., Canson, Daffodil M., Bis-Brewer, Dana, Cass, Ashley, Tchourbanov, Alexander, Zimmermann, Heather, Byrne, Alicia B., Pesaran, Tina, Karam, Rachid, Harrison, Steven M., Spurdle, Amanda B., Biesecker, Leslie G., Harrison, Steven M., Tayoun, Ahmad A., Berg, Jonathan S., Brenner, Steven E., Cutting, Garry R., Ellard, Sian, Greenblatt, Marc S., Kang, Peter, Karbassi, Izabela, Karchin, Rachel, Mester, Jessica, O’Donnell-Luria, Anne, Pesaran, Tina, Plon, Sharon E., Rehm, Heidi L., Strande, Natasha T., Tavtigian, Sean V., Topper, Scott

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The “All of Us” Research Program von Denny, Joshua C, Rutter, Joni L, Goldstein, David B, Philippakis, Anthony, Smoller, Jordan W, Jenkins, Gwynne, Dishman, Eric

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Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53 -Dependent Manner von McDonald, James I, Diab, Noor, Arthofer, Elisa, Hadley, Melissa, Kanholm, Tomas, Rentia, Uzma, Gomez, Stephanie, Yu, Angela, Grundy, Erin E, Cox, Olivia, Topper, Michael J, Xing, Xiaoyun, Strissel, Pamela L, Strick, Reiner, Wang, Ting, Baylin, Stephen B, Chiappinelli, Katherine B

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Early Cambrian chronostratigraphy and geochronology of South Australia von Betts, Marissa J., Paterson, John R., Jacquet, Sarah M., Andrew, Anita S., Hall, Philip A., Jago, James B., Jagodzinski, Elizabeth A., Preiss, Wolfgang V., Crowley, James L., Birch, Sienna A., Mathewson, Ciaran P., García-Bellido, Diego C., Topper, Timothy P., Skovsted, Christian B., Brock, Glenn A.

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Scaling resolution of variant classification differences in ClinVar between 41 clinical laboratories through an outlier approach von Harrison, Steven M., Dolinksy, Jill S., Chen, Wenjie, Collins, Christin D., Das, Soma, Deignan, Joshua L., Garber, Kathryn B., Garcia, John, Jarinova, Olga, Knight Johnson, Amy E., Koskenvuo, Juha W., Lee, Hane, Mao, Rong, Mar‐Heyming, Rebecca, McFaddin, Andrew S., Moyer, Krista, Nagan, Narasimhan, Rentas, Stefan, Santani, Avni B., Seppälä, Eija H., Shirts, Brian H., Tidwell, Timothy, Topper, Scott, Vincent, Lisa M., Vinette, Kathy, Rehm, Heidi L.

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Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington von McMichael, Temet M, Currie, Dustin W, Clark, Shauna, Pogosjans, Sargis, Kay, Meagan, Schwartz, Noah G, Lewis, James, Baer, Atar, Kawakami, Vance, Lukoff, Margaret D, Ferro, Jessica, Brostrom-Smith, Claire, Rea, Thomas D, Sayre, Michael R, Riedo, Francis X, Russell, Denny, Hiatt, Brian, Montgomery, Patricia, Rao, Agam K, Chow, Eric J, Tobolowsky, Farrell, Hughes, Michael J, Bardossy, Ana C, Oakley, Lisa P, Jacobs, Jesica R, Stone, Nimalie D, Reddy, Sujan C, Jernigan, John A, Honein, Margaret A, Clark, Thomas A, Duchin, Jeffrey S

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Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children von Moler, Frank W, Silverstein, Faye S, Holubkov, Richard, Slomine, Beth S, Christensen, James R, Nadkarni, Vinay M, Meert, Kathleen L, Browning, Brittan, Pemberton, Victoria L, Page, Kent, Gildea, Marianne R, Scholefield, Barnaby R, Shankaran, Seetha, Hutchison, Jamie S, Berger, John T, Ofori-Amanfo, George, Newth, Christopher J.L, Topjian, Alexis, Bennett, Kimberly S, Koch, Joshua D, Pham, Nga, Chanani, Nikhil K, Pineda, Jose A, Harrison, Rick, Dalton, Heidi J, Alten, Jeffrey, Schleien, Charles L, Goodman, Denise M, Zimmerman, Jerry J, Bhalala, Utpal S, Schwarz, Adam J, Porter, Melissa B, Shah, Samir, Fink, Ericka L, McQuillen, Patrick, Wu, Theodore, Skellett, Sophie, Thomas, Neal J, Nowak, Jeffrey E, Baines, Paul B, Pappachan, John, Mathur, Mudit, Lloyd, Eric, van der Jagt, Elise W, Dobyns, Emily L, Meyer, Michael T, Sanders, Ronald C, Clark, Amy E, Dean, J. Michael

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Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency von McLaughlin, Lena J., Stojanovic, Lora, Kogan, Aksinija A., Rutherford, Julia L., Choi, Eun Yong, Yen, Ray-Whay Chiu, Xia, Limin, Zou, Ying, Lapidus, Rena G., Baylin, Stephen B., Topper, Michael J., Rassool, Feyruz V.

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The morphological disparity, ecological evolution and palaeobiogeography of Palaeozoic hyoliths von Liu, Fan, Topper, Timothy P, Strotz, Luke C, Liang, Yue, Skovsted, Christian B, Zhang, Zhifei

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Elevated CD4 + T-cell glucose metabolism in HIV+ women with diabetes mellitus von Butterfield, Tiffany R., Hanna, David B., Kaplan, Robert C., Xue, Xiaonan, Kizer, Jorge R., Durkin, Helen G., Kassaye, Seble G., Nowicki, Marek, Tien, Phyllis C., Topper, Elizabeth T., Floris-Moore, Michelle A., Titanji, Kehmia, Fischl, Margaret A., Heath, Sonya, Palmer, Clovis S., Landay, Alan L., Anzinger, Joshua J.

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Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia von Kogan, Aksinija A, Topper, Michael J, Dellomo, Anna J, Stojanovic, Lora, McLaughlin, Lena J, Creed, T Michael, Eberly, Christian L, Kingsbury, Tami J, Baer, Maria R, Kessler, Michael D, Baylin, Stephen B, Rassool, Feyruz V

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A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy von Jang, H Josh, Hostetter, Galen, Macfarlane, Alexander W, Madaj, Zachary, Ross, Eric A, Hinoue, Toshinori, Kulchycki, Justin R, Burgos, Ryan S, Tafseer, Mahvish, Alpaugh, R Katherine, Schwebel, Candice L, Kokate, Rutika, Geynisman, Daniel M, Zibelman, Matthew R, Ghatalia, Pooja, Nichols, Peter W, Chung, Woonbok, Madzo, Jozef, Hahn, Noah M, Quinn, David I, Issa, Jean-Pierre J, Topper, Michael J, Baylin, Stephen B, Shen, Hui, Campbell, Kerry S, Jones, Peter A, Plimack, Elizabeth R

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The Brain’s Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample von Stringaris, Argyris, Vidal-Ribas Belil, Pablo, Artiges, Eric, Lemaitre, Hervé, Gollier-Briant, Fanny, Wolke, Selina, Vulser, Hélène, Miranda, Ruben, Penttilä, Jani, Struve, Maren, Fadai, Tahmine, Kappel, Viola, Grimmer, Yvonne, Goodman, Robert, Poustka, Luise, Conrod, Patricia, Cattrell, Anna, Banaschewski, Tobias, Bokde, Arun L.W., Bromberg, Uli, Büchel, Christian, Flor, Herta, Frouin, Vincent, Gallinat, Juergen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Nees, Frauke, Papadopoulos, Dimitri, Paus, Tomas, Smolka, Michael N., Walter, Henrik, Whelan, Rob, Martinot, Jean-Luc, Schumann, Gunter, Paillère-Martinot, Marie-Laure

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