Regulation of mRNA translation by signaling pathways von Roux, Philippe P, Topisirovic, Ivan

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mRNA translation and energy metabolism in cancer: the role of the MAPK and mTORC1 pathways von Topisirovic, I, Sonenberg, N

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The integrated stress response exposes a therapeutic vulnerability in KRAS driven lung cancer von Ghaddar, N., Wang, S., Woodvine, B., Krishnamoorthy, J., Darini, C., Van Hoef, V., Popper, H., Topisirovic, I., Larsson, O., Le Quesne, J., Koromilas, A.

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RACK1 Function in Cell Motility and Protein Synthesis von Gandin, Valentina, Senft, Daniela, Topisirovic, Ivan, Ronai, Ze'ev A

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The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner von Im, Y K, La Selva, R, Gandin, V, Ha, J R, Sabourin, V, Sonenberg, N, Pawson, T, Topisirovic, I, Ursini-Siegel, J

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The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth von Topisirovic, Ivan, Culjkovic, Biljana, Cohen, Natalie, Perez, Jacqueline M., Skrabanek, Lucy, Borden, Katherine L.B.

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mTOR coordinates protein synthesis, mitochondrial activity and proliferation von Morita, Masahiro, Gravel, Simon-Pierre, Hulea, Laura, Larsson, Ola, Pollak, Michael, St-Pierre, Julie, Topisirovic, Ivan

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Translational control of immune responses: from transcripts to translatomes von Piccirillo, Ciriaco A, Bjur, Eva, Topisirovic, Ivan, Sonenberg, Nahum, Larsson, Ola

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mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1 von Morita, Masahiro, Prudent, Julien, Basu, Kaustuv, Goyon, Vanessa, Katsumura, Sakie, Hulea, Laura, Pearl, Dana, Siddiqui, Nadeem, Strack, Stefan, McGuirk, Shawn, St-Pierre, Julie, Larsson, Ola, Topisirovic, Ivan, Vali, Hojatollah, McBride, Heidi M., Bergeron, John J., Sonenberg, Nahum

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Generally applicable transcriptome-wide analysis of translation using anota2seq von Oertlin, Christian, Lorent, Julie, Murie, Carl, Furic, Luc, Topisirovic, Ivan, Larsson, Ola

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An antiviral disulfide compound blocks interaction between arenavirus Z protein and cellular promyelocytic leukemia protein von García, C.C., Topisirovic, I., Djavani, M., Borden, K.L.B., Damonte, E.B., Salvato, M.S.

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mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation von Morita, Masahiro, Gravel, Simon-Pierre, Chénard, Valérie, Sikström, Kristina, Zheng, Liang, Alain, Tommy, Gandin, Valentina, Avizonis, Daina, Arguello, Meztli, Zakaria, Chadi, McLaughlan, Shannon, Nouet, Yann, Pause, Arnim, Pollak, Michael, Gottlieb, Eyal, Larsson, Ola, St-Pierre, Julie, Topisirovic, Ivan, Sonenberg, Nahum

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Regulation of gene expression via translational buffering von Kusnadi, Eric P., Timpone, Clelia, Topisirovic, Ivan, Larsson, Ola, Furic, Luc

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mTOR-sensitive translation: Cleared fog reveals more trees von Masvidal, Laia, Hulea, Laura, Furic, Luc, Topisirovic, Ivan, Larsson, Ola

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Distinct perturbation of the translatome by the antidiabetic drug metformin von Larsson, Ola, Morita, Masahiro, Topisirovic, Ivan, Alain, Tommy, Blouin, Marie-Jose, Pollak, Michael, Sonenberg, Nahum

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Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation von Hipolito, Victoria E B, Diaz, Jacqueline A, Tandoc, Kristofferson V, Oertlin, Christian, Ristau, Johannes, Chauhan, Neha, Saric, Amra, Mclaughlan, Shannon, Larsson, Ola, Topisirovic, Ivan, Botelho, Roberto J

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nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs von Gandin, Valentina, Masvidal, Laia, Hulea, Laura, Gravel, Simon-Pierre, Cargnello, Marie, McLaughlan, Shannon, Cai, Yutian, Balanathan, Preetika, Morita, Masahiro, Rajakumar, Arjuna, Furic, Luc, Pollak, Michael, Porco, Jr, John A, St-Pierre, Julie, Pelletier, Jerry, Larsson, Ola, Topisirovic, Ivan

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A Unique ISR Program Determines Cellular Responses to Chronic Stress von Guan, Bo-Jhih, van Hoef, Vincent, Jobava, Raul, Elroy-Stein, Orna, Valasek, Leos S., Cargnello, Marie, Gao, Xing-Huang, Krokowski, Dawid, Merrick, William C., Kimball, Scot R., Komar, Anton A., Koromilas, Antonis E., Wynshaw-Boris, Anthony, Topisirovic, Ivan, Larsson, Ola, Hatzoglou, Maria

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mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs von Dowling, Ryan J.O, Topisirovic, Ivan, Alain, Tommy, Bidinosti, Michael, Fonseca, Bruno D, Petroulakis, Emmanuel, Wang, Xiaoshan, Larsson, Ola, Selvaraj, Anand, Liu, Yi, Kozma, Sara C, Thomas, George, Sonenberg, Nahum

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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth von Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal

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