Design, Synthesis, and Evaluation of the Highly Selective and Potent G‑Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure von Okawa, Tomohiro, Aramaki, Yoshio, Yamamoto, Mitsuo, Kobayashi, Toshitake, Fukumoto, Shoji, Toyoda, Yukio, Henta, Tsutomu, Hata, Akito, Ikeda, Shota, Kaneko, Manami, Hoffman, Isaac D, Sang, Bi-Ching, Zou, Hua, Kawamoto, Tetsuji

Volltext

Orally Active CCR5 Antagonists as Anti-HIV-1 Agents: Synthesis and Biological Activity of 1-Benzothiepine 1,1-Dioxide and 1-Benzazepine Derivatives Containing a Tertiary Amine Moie... von Seto, Masaki, Aramaki, Yoshio, Okawa, Tomohiro, Miyamoto, Naoki, Aikawa, Katsuji, Kanzaki, Naoyuki, Niwa, Shin-ichi, Iizawa, Yuji, Baba, Masanori, Shiraishi, Mitsuru

Volltext

Synthesis of 1-Benzothiepine and 1-Benzazepine Derivatives as Orally Active CCR5 Antagonists von Aramaki, Yoshio, Seto, Masaki, Okawa, Tomohiro, Oda, Tsuneo, Kanzaki, Naoyuki, Shiraishi, Mitsuru

Volltext

Synthesis of pyrazino[2,3- e][1,4]diazepin-5-one and pyrazino[2,3- e]pyrrolo[1,2- a][1,4]diazepin-5-one derivatives via the intramolecular aza-Wittig reaction von Okawa, Tomohiro, Eguchi, Shoji

Volltext

A Selective Bombesin Receptor Subtype 3 Agonist Promotes Weight Loss in Male Diet-Induced-Obese Rats With Circadian Rhythm Change von Nio, Yasunori, Hotta, Natsu, Maruyama, Minoru, Hamagami, Kenichi, Nagi, Toshimi, Funata, Masaaki, Sakamoto, Junichi, Nakakariya, Masanori, Amano, Nobuyuki, Okawa, Tomohiro, Arikawa, Yasuyoshi, Sasaki, Shinobu, Okuda, Shoki, Kasai, Shizuo, Habata, Yugo, Nagisa, Yasutaka

Volltext

Facile synthesis of pyrazino[2,3- e][1,4]diazepine derivatives via the intramolecular aza-Wittig reaction von Okawa, Tomohiro, Eguchi, Shoji

Volltext

Bombesin receptor subtype‐3‐expressing neurons regulate energy homeostasis through a novel neuronal pathway in the hypothalamus von Maruyama, Minoru, Hotta, Natsu, Nio, Yasunori, Hamagami, Kenichi, Nagi, Toshimi, Funata, Masaaki, Sakamoto, Junichi, Nakakariya, Masanori, Amano, Nobuyuki, Nishida, Mayumi, Okawa, Tomohiro, Arikawa, Yasuyoshi, Sasaki, Shinobu, Kasai, Shizuo, Nagisa, Yasutaka, Habata, Yugo, Mori, Masaaki

Volltext

Synthesis, Structure–Activity Relationship, and Pharmacological Studies of Novel Melanin-Concentrating Hormone Receptor 1 Antagonists 3-Aminomethylquinolines: Reducing Human Ether-... von Kasai, Shizuo, Kamata, Makoto, Masada, Shinichi, Kunitomo, Jun, Kamaura, Masahiro, Okawa, Tomohiro, Takami, Kazuaki, Ogino, Hitomi, Nakano, Yoshihide, Ashina, Shuntarou, Watanabe, Kaoru, Kaisho, Tomoko, Imai, Yumi N, Ryu, Sunghi, Nakayama, Masaharu, Nagisa, Yasutaka, Takekawa, Shiro, Kato, Koki, Murata, Toshiki, Suzuki, Nobuhiro, Ishihara, Yuji

Volltext

The First Total Synthesis of (−)-Benzomalvin A via Intramolecular Aza-Wittig Reactions von Sugimori, Toshiyuki, Okawa, Tomohiro, Eguchi, Shoji, Yashima, Eiji, Okamoto, Yoshio

Volltext

Chemoselectivity in the Intramolecular Aza-Wittig Reaction of N-[2-(Trisubstituted-phosphoranylidene)aminobenzoyl]-2-pyridone-5-carboxylic Acid Derivatives von Okawa, Tomohiro, Sugimori, Toshiyuki, Eguchi, Shoji, Kakehi, Akikazu

Volltext

Synthesis of Optically Active Vasicinone Based on Intramolecular Aza-Wittig Reaction and Asymmetric Oxidation1 von Eguchi, Shoji, Suzuki, Toshio, Okawa, Tomohiro, Matsushita, Yuji, Yashima, Eiji, Okamoto, Yoshio

Volltext

Synthesis of Optically Active Vasicinone Based on Intramolecular Aza-Wittig Reaction and Asymmetric Oxidation(1) von Eguchi, Shoji, Suzuki, Toshio, Okawa, Tomohiro, Matsushita, Yuji, Yashima, Eiji, Okamoto, Yoshio

Volltext

The first total synthesis of (−)-benzomalvin A and benzomalvin B via the intramolecular aza-Wittig reactions von Sugimori, Toshiyuki, Okawa, Tomohiro, Eguchi, Shoji, Kakehi, Akikazu, Yashima, Eiji, Okamoto, Yoshio

Volltext

FUSED HETEROARYL COMPOUNDS AND THEIR USE AS CAMKII INHIBITORS von MACCOSS, Malcolm, SHIOKAWA, Zenyu, KAWADA, Akira, SHIBUYA, Akito, SHIRAI, Junya, OKAWA, Tomohiro, NAKAHATA, Takashi, MATSUNAGA, Nobuyuki, MIYAMOTO, Yasufumi

Volltext bestellen

FUSED HETEROARYL COMPOUNDS AND THEIR USE AS CAMKII INHIBITORS von MACCOSS, Malcolm, SHIOKAWA, Zenyu, KAWADA, Akira, SHIRAI, Junya, OKAWA, Tomohiro, SHIBUYA, Akito, NAKAHATA, Takashi, MATSUNAGA, Nobuyuki, MIYAMOTO, Yasufumi

Volltext bestellen

HETEROCYCLIC COMPOUND von TOKUHARA, HIDEKAZU, OGURO, YUYA, IKEDA, SHUHEI, AIDA, JUMPEI, OKAWA, TOMOHIRO, NAKAMURA, MINORU, MURAKAMI, MASATAKA, SUGIYAMA, HIDEYUKI

Volltext bestellen

Subordination in Japanese insolvency proceedings von Okawa, Tomohiro

Volltext

SUBSTITUTED IMIDAZO [1,2-b] PYRIDAZINES AND [1, 2, 4] TRIAZOLO [ 4,3-b] PYRIDAZINES AS CAMKII INHIBITORS von MACCOSS, Malcolm, SHIOKAWA, Zenyu, KAWADA, Akira, SHIRAI, Junya, OKAWA, Tomohiro, SHIBUYA, Akito, NAKAHATA, Takashi, MATSUNAGA, Nobuyuki, MIYAMOTO, Yasufumi

Volltext bestellen

AMINOPYRIMIDINE COMPOUND von MACCOSS, Malcolm, SHIOKAWA, Zenyu, SHIRAI, Junya, OKAWA, Tomohiro, SHIBUYA, Akito, NAKAHATA, Takashi, MATSUNAGA, Nobuyuki, MIYAMOTO, Yasufumi

Volltext bestellen

HETEROCYCLIC COMPOUND von TOKUHARA, HIDEKAZU, OGURO, YUYA, IKEDA, SHUHEI, AIDA, JUMPEI, OKAWA, TOMOHIRO, NAKAMURA, MINORU, MURAKAMI, MASATAKA, SUGIYAMA, HIDEYUKI

Volltext bestellen