The effects of mutational processes and selection on driver mutations across cancer types von Temko, Daniel, Tomlinson, Ian P. M., Severini, Simone, Schuster-Böckler, Benjamin, Graham, Trevor A.

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase von Frezza, Christian, Zheng, Liang, Folger, Ori, Rajagopalan, Kartik N., MacKenzie, Elaine D., Jerby, Livnat, Micaroni, Massimo, Chaneton, Barbara, Adam, Julie, Hedley, Ann, Kalna, Gabriela, Tomlinson, Ian P. M., Pollard, Patrick J., Watson, Dave G., Deberardinis, Ralph J., Shlomi, Tomer, Ruppin, Eytan, Gottlieb, Eyal

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Prognostic significance of POLE proofreading mutations in endometrial cancer von Church, David N, Stelloo, Ellen, Nout, Remi A, Valtcheva, Nadejda, Depreeuw, Jeroen, ter Haar, Natalja, Noske, Aurelia, Amant, Frederic, Tomlinson, Ian P M, Wild, Peter J, Lambrechts, Diether, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Smit, Vincent T H B M, Creutzberg, Carien L, Bosse, Tjalling

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Mitochondrial tumour suppressors: a genetic and biochemical update von Gottlieb, Eyal, Tomlinson, Ian P. M

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Chromosomal Instability Confers Intrinsic Multidrug Resistance von LEE, Alvin J. X, ENDESFELDER, David, KSCHISCHO, Maik, SWANTON, Charles, ROWAN, Andrew J, WALTHER, Axel, BIRKBAK, Nicolai J, ANDREW FUTREAL, P, DOWNWARD, Julian, SZALLASI, Zoltan, TOMLINSON, Ian P. M, HOWELL, Michael

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Measuring single cell divisions in human tissues from multi-region sequencing data von Werner, Benjamin, Case, Jack, Williams, Marc J., Chkhaidze, Ketevan, Temko, Daniel, Fernández-Mateos, Javier, Cresswell, George D., Nichol, Daniel, Cross, William, Spiteri, Inmaculada, Huang, Weini, Tomlinson, Ian P. M., Barnes, Chris P., Graham, Trevor A., Sottoriva, Andrea

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Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types von Rao, Srinivasa R, Protheroe, Andrew, Cerundolo, Lucia, Maldonado-Perez, David, Browning, Lisa, Lamb, Alastair D, Bryant, Richard J, Mills, Ian G, Woodcock, Dan J, Hamdy, Freddie C, Tomlinson, Ian P M, Verrill, Clare

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PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis von SAKTHIANANDESWAREN, Anuratha, CHRISTIE, Michael, RAMSAY, Robert G, PHESSE, Toby J, ERNST, Matthias, JEFFERY, Rosemary E, POULSOM, Richard, LEEDHAM, Simon J, SEGDITSAS, Stefania, TOMLINSON, Ian P. M, BERNHARD, Oliver K, SIMPSON, Richard J, D'ANDRETI, Carla, WALKER, Francesca, FAUX, Maree C, CHURCH, Nicole, CATIMEL, Bruno, FLANAGAN, Dustin J, VINCAN, Elizabeth, SIEBER, Oliver M, TSUI, Cary, JORISSEN, Robert N, SHAN LI, FLEMING, Nicholas I, GIBBS, Peter, LIPTON, Lara, MALATERRE, Jordane

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Author Correction: The effects of mutational processes and selection on driver mutations across cancer types von Temko, Daniel, Tomlinson, Ian P. M., Severini, Simone, Schuster-Böckler, Benjamin, Graham, Trevor A.

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The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency von Bayley, Jean-Pierre, Launonen, Virpi, Tomlinson, Ian P M

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Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer von MOURADOV, Dmitri, SLOGGETT, Clare, O'CONNOR, Liam, WILDING, Jennifer L, BICKNELL, David, TOMLINSON, Ian P. M, BODMER, Walter F, MARIADASON, John M, SIEBER, Oliver M, JORISSEN, Robert N, LOVE, Christopher G, SHAN LI, BURGESS, Antony W, ARANGO, Diego, STRAUSBERG, Robert L, BUCHANAN, Daniel, WORMALD, Samuel

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Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer von DOMINGO, Enric, CHURCH, David N, SIEBER, Oliver, RAMAMOORTHY, Rajarajan, YANAGISAWA, Yoko, JOHNSTONE, Elaine, DAVIDSON, Brian, KERR, David J, TOMLINSON, Ian P. M, MIDGLEY, Rachel

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The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer von Elsaba, Tarek M A, Martinez-Pomares, Luisa, Robins, Adrian R, Crook, Simon, Seth, Rashmi, Jackson, Darryl, McCart, Amy, Silver, Andrew R, Tomlinson, Ian P M, Ilyas, Mohammad

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Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas von DOUGLAS, Eleanor J, FIEGLER, Heike, ROWAN, Andrew, HALFORD, Sarah, BICKNELL, David C, BODMER, Walter, TOMLINSON, Ian P. M, CARTER, Nigel P

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Molecular genetic evidence that endometriosis is a precursor of ovarian cancer von Prowse, Amanda H., Manek, Sanjiv, Varma, Rajesh, Liu, Jinsong, Godwin, Andrew K., Maher, Eamonn R., Tomlinson, Ian P.M., Kennedy, Stephen H.

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Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study von Zhang, Xiaomeng, Theodoratou, Evropi, Li, Xue, Farrington, Susan M., Law, Philip J., Broderick, Peter, Walker, Marion, Klimentidis, Yann C., Rees, Jessica M. B., Houlston, Richard S., Tomlinson, Ian P. M., Burgess, Stephen, Campbell, Harry, Dunlop, Malcolm G., Timofeeva, Maria

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What can be learnt about disease progression in breast cancer dormancy from relapse data? von Willis, Lisa, Graham, Trevor A, Alarcón, Tomás, Alison, Malcolm R, Tomlinson, Ian P M, Page, Karen M

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Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank von Zhang, Xiaomeng, Li, Xue, He, Yazhou, Law, Philip J., Farrington, Susan M., Campbell, Harry, Tomlinson, Ian P. M., Houlston, Richard S., Dunlop, Malcolm G., Timofeeva, Maria, Theodoratou, Evropi

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Multiple Rare Variants in Different Genes Account for Multifactorial Inherited Susceptibility to Colorectal Adenomas von Fearnhead, Nicola S., Wilding, Jennifer L., Winney, Bruce, Tonks, Susan, Bartlett, Sylvia, Bicknell, David C., Ian P. M. Tomlinson, Neil J. Mc C. Mortensen, Bodmer, Walter F.

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Adult Leydig Cell Tumors of the Testis Caused by Germline Fumarate Hydratase Mutations von Carvajal-Carmona, Luis G., Alam, N. Afrina, Pollard, Patrick J., Jones, Angela M., Barclay, Ella, Wortham, Noel, Pignatelli, Massimo, Freeman, Alex, Pomplun, Sabine, Ellis, Ian, Poulsom, Richard, El-Bahrawy, Mona A., Berney, Daniel M., Tomlinson, Ian P. M.

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