The Mutation Rate and Cancer von Tomlinson, I. P. M., Novelli, M. R., Bodmer, W. F.

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Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk von Webb, E, Broderick, P, Chandler, I, Lubbe, S, Penegar, S, Tomlinson, I P M, Houlston, R S

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TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres von Jones, A M, Beggs, A D, Carvajal-Carmona, L, Farrington, S, Tenesa, A, Walker, M, Howarth, K, Ballereau, S, Hodgson, S V, Zauber, A, Bertagnolli, M, Midgley, R, Campbell, H, Kerr, D, Dunlop, M G, Tomlinson, I P M

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Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia von Enciso-Mora, V, Hosking, F J, Sheridan, E, Kinsey, S E, Lightfoot, T, Roman, E, Irving, J A E, Tomlinson, I P M, Allan, J M, Taylor, M, Greaves, M, Houlston, R S

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comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence von Jones, AM, Mitter, R, Springall, R, Graham, T, Winter, E, Gillett, C, Hanby, AM, Tomlinson, IPM, Sawyer, EJ

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Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs von Holt, Lucy J., Basran, Amrik, Jones, Kate, Chorlton, Jennifer, Jespers, Laurent S., Brewis, Neil D., Tomlinson, Ian M.

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Isolation of high affinity human antibodies directly from large synthetic repertoires von Griffiths, A.D., Williams, S.C., Hartley, O., Tomlinson, I.M., Waterhouse, P., Crosby, W.L., Kontermann, R.E., Jones, P.T., Low, N.M., Allison, T.J.

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The structural repertoire of the human V kappa domain von Tomlinson, I. M., Cox, J. P., Gherardi, E., Lesk, A. M., Chothia, C.

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β -Catenin Mutations in Cell Lines Established from Human Colorectal Cancers von Ilyas, M., Tomlinson, I. P. M., Rowan, A., Pignatelli, M., Bodmer, W. F.

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APC and the three-hit hypothesis von Segditsas, S, Rowan, A J, Howarth, K, Jones, A, Leedham, S, Wright, N A, Gorman, P, Chambers, W, Domingo, E, Roylance, R R, Sawyer, E J, Sieber, O M, Tomlinson, I P M

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Location in the large bowel influences the APC mutations observed in FAP adenomas von Will, O. C., Leedham, S. J., Elia, G., Phillips, R. K. S., Clark, S. K., Tomlinson, I. P. M.

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Molecular classification and genetic pathways in hyperplastic polyposis syndrome von Carvajal-Carmona, LG, Howarth, KM, Lockett, M, Polanco-Echeverry, GM, Volikos, E, Gorman, M, Barclay, E, Martin, L, Jones, AM, Saunders, B, Guenther, T, Donaldson, A, Paterson, J, Frayling, I, Novelli, MR, Phillips, R, Thomas, HJW, Silver, A, Atkin, W, Tomlinson, IPM

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mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours von Jones, AM, Mitter, R, Poulsom, R, Gillett, C, Hanby, AM, Consortium, Phyllodes Tumour, Tomlinson, IPM, Sawyer, EJ

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Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation von Sieber, O M, Segditsas, S, Knudsen, A L, Zhang, J, Luz, J, Rowan, A J, Spain, S L, Thirlwell, C, Howarth, K M, Jaeger, E E M, Robinson, J, Volikos, E, Silver, A, Kelly, G, Aretz, S, Frayling, I, Hutter, P, Dunlop, M, Guenther, T, Neale, K, Phillips, R, Heinimann, K, Tomlinson, I P M

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Sequence and Evolution of the Human Germline V λRepertoire von Williams, Samuel C., Frippiat, Jean-Pol, Tomlinson, Ian M., Ignatovich, Olga, Lefranc, Marie-Paule, Winter, Greg

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Domain antibodies: proteins for therapy von Holt, Lucy J, Herring, Chris, Jespers, Laurent S, Woolven, Benjamin P, Tomlinson, Ian M

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Antibody arrays for high-throughput screening of antibody-antigen interactions von de Wildt, Ruud M. T, Tomlinson, Ian M, Mundy, Chris R, Gorick, Barbara D

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Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden von Cazier, J. -B., Rao, S. R., McLean, C. M., Walker, A. K., Wright, B. J., Jaeger, E. E. M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J. W., Tomlinson, I. P. M., Kiltie, A. E., Hamdy, F. C.

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Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis von Christie, M, Jorissen, R N, Mouradov, D, Sakthianandeswaren, A, Li, S, Day, F, Tsui, C, Lipton, L, Desai, J, Jones, I T, McLaughlin, S, Ward, R L, Hawkins, N J, Ruszkiewicz, A R, Moore, J, Burgess, A W, Busam, D, Zhao, Q, Strausberg, R L, Simpson, A J, Tomlinson, I P M, Gibbs, P, Sieber, O M

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Whole-Gene APC Deletions Cause Classical Familial Adenomatous Polyposis, but not Attenuated Polyposis or "Multiple" Colorectal Adenomas von Sieber, O. M., Lamlum, H., Crabtree, M.D., Rowan, A. J., Barclay, E., Lipton, L., Hodgson, S., Thomas, H. J. W., Neale, K., Phillips, R. K. S., Farrington, S. M., Dunlop, M. G., Mueller, H. J., Bisgaard, M. L., Bulow, S., Fidalgo, P., Albuquerque, C., Scarano, M. I., Bodmer, W., Tomlinson, I. P. M., Heinimann, K.

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