Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1 von Tomazou, Eleni M., Sheffield, Nathan C., Schmidl, Christian, Schuster, Michael, Schönegger, Andreas, Datlinger, Paul, Kubicek, Stefan, Bock, Christoph, Kovar, Heinrich

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EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex von Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A

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Quantitative comparison of genome-wide DNA methylation mapping technologies von Brinkman, Arie B, Meissner, Alexander, Gu, Hongcang, Müller, Fabian, Bock, Christoph, Jäger, Natalie, Tomazou, Eleni M, Stunnenberg, Hendrik G, Gnirke, Andreas, Simmer, Femke

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Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression von Terlecki-Zaniewicz, Stefan, Humer, Theresa, Eder, Thomas, Schmoellerl, Johannes, Heyes, Elizabeth, Manhart, Gabriele, Kuchynka, Natalie, Parapatics, Katja, Liberante, Fabio G., Müller, André C., Tomazou, Eleni M., Grebien, Florian

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Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis von Fetahu, Irfete S., Esser-Skala, Wolfgang, Dnyansagar, Rohit, Sindelar, Samuel, Rifatbegovic, Fikret, Bileck, Andrea, Skos, Lukas, Bozsaky, Eva, Lazic, Daria, Shaw, Lisa, Tötzl, Marcus, Tarlungeanu, Dora, Bernkopf, Marie, Rados, Magdalena, Weninger, Wolfgang, Tomazou, Eleni M., Bock, Christoph, Gerner, Christopher, Ladenstein, Ruth, Farlik, Matthias, Fortelny, Nikolaus, Taschner-Mandl, Sabine

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MIRA: an R package for DNA methylation-based inference of regulatory activity von Lawson, John T, Tomazou, Eleni M, Bock, Christoph, Sheffield, Nathan C

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A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis von Bäckdahl, Liselotte, Li, Heng, Jackson, David K, Howe, Kevin L, Tavaré, Simon, Gräf, Stefan, Herrero, Javier, Johnson, Nathan, Durbin, Richard, Thorne, Natalie P, Turner, Daniel J, Tomazou, Eleni M, Miretti, Marcos M, Birney, Ewan, Hubbard, Tim J P, Beck, Stephan, Rakyan, Vardhman K, Herberth, Marlis, Marioni, John C, Down, Thomas A, Flicek, Paul, Kulesha, Eugene

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An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs) von Rakyan, Vardhman K, Down, Thomas A, Thorne, Natalie P, Flicek, Paul, Kulesha, Eugene, Gräf, Stefan, Tomazou, Eleni M, Bäckdahl, Liselotte, Johnson, Nathan, Herberth, Marlis, Howe, Kevin L, Jackson, David K, Miretti, Marcos M, Fiegler, Heike, Marioni, John C, Birney, Ewan, Hubbard, Tim J P, Carter, Nigel P, Tavaré, Simon, Beck, Stephan

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Ewing sarcoma von Grünewald, Thomas G. P., Cidre-Aranaz, Florencia, Surdez, Didier, Tomazou, Eleni M., de Álava, Enrique, Kovar, Heinrich, Sorensen, Poul H., Delattre, Olivier, Dirksen, Uta

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DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma von Sheffield, Nathan C, Pierron, Gaelle, Klughammer, Johanna, Datlinger, Paul, Schönegger, Andreas, Schuster, Michael, Hadler, Johanna, Surdez, Didier, Guillemot, Delphine, Lapouble, Eve, Freneaux, Paul, Champigneulle, Jacqueline, Bouvier, Raymonde, Walder, Diana, Ambros, Ingeborg M, Hutter, Caroline, Sorz, Eva, Amaral, Ana T, de Álava, Enrique, Schallmoser, Katharina, Strunk, Dirk, Rinner, Beate, Liegl-Atzwanger, Bernadette, Huppertz, Berthold, Leithner, Andreas, de Pinieux, Gonzague, Terrier, Philippe, Laurence, Valérie, Michon, Jean, Ladenstein, Ruth, Holter, Wolfgang, Windhager, Reinhard, Dirksen, Uta, Ambros, Peter F, Delattre, Olivier, Kovar, Heinrich, Bock, Christoph, Tomazou, Eleni M

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Quantification of Translocation-Specific ctDNA Provides an Integrating Parameter for Early Assessment of Treatment Response and Risk Stratification in Ewing Sarcoma von Krumbholz, Manuela, Eiblwieser, Johanna, Ranft, Andreas, Zierk, Jakob, Schmidkonz, Christian, Stütz, Adrian M, Peneder, Peter, Tomazou, Eleni M, Agaimy, Abbas, Bäuerle, Tobias, Hartmann, Wolfgang, Dirksen, Uta, Metzler, Markus

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High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma von Grissenberger, Sarah, Sturtzel, Caterina, Wenninger-Weinzierl, Andrea, Radic-Sarikas, Branka, Scheuringer, Eva, Bierbaumer, Lisa, Etienne, Vesnie, Némati, Fariba, Pascoal, Susana, Tötzl, Marcus, Tomazou, Eleni M., Metzelder, Martin, Putz, Eva M., Decaudin, Didier, Delattre, Olivier, Surdez, Didier, Kovar, Heinrich, Halbritter, Florian, Distel, Martin

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LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data von Peneder, Peter, Bock, Christoph, Tomazou, Eleni M

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Sarcoma treatment in the era of molecular medicine von Grünewald, Thomas GP, Alonso, Marta, Avnet, Sofia, Banito, Ana, Burdach, Stefan, Cidre‐Aranaz, Florencia, Di Pompo, Gemma, Distel, Martin, Dorado‐Garcia, Heathcliff, Garcia‐Castro, Javier, González‐González, Laura, Grigoriadis, Agamemnon E, Kasan, Merve, Koelsche, Christian, Krumbholz, Manuela, Lecanda, Fernando, Lemma, Silvia, Longo, Dario L, Madrigal‐Esquivel, Claudia, Morales‐Molina, Álvaro, Musa, Julian, Ohmura, Shunya, Ory, Benjamin, Pereira‐Silva, Miguel, Perut, Francesca, Rodriguez, Rene, Seeling, Carolin, Al Shaaili, Nada, Shaabani, Shabnam, Shiavone, Kristina, Sinha, Snehadri, Tomazou, Eleni M, Trautmann, Marcel, Vela, Maria, Versleijen‐Jonkers, Yvonne MH, Visgauss, Julia, Zalacain, Marta, Schober, Sebastian J, Lissat, Andrej, English, William R, Baldini, Nicola, Heymann, Dominique

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Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis von Tomazou, Eleni M, Rakyan, Vardhman K, Lefebvre, Gregory, Andrews, Robert, Ellis, Peter, Jackson, David K, Langford, Cordelia, Francis, Matthew D, Bäckdahl, Liselotte, Miretti, Marcos, Coggill, Penny, Ottaviani, Diego, Sheer, Denise, Murrell, Adele, Beck, Stephan

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EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma von Katschnig, A M, Kauer, M O, Schwentner, R, Tomazou, E M, Mutz, C N, Linder, M, Sibilia, M, Alonso, J, Aryee, D N T, Kovar, H

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Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation von Javaheri, Tahereh, Kazemi, Zahra, Pencik, Jan, Pham, Ha Tt, Kauer, Maximilian, Noorizadeh, Rahil, Sax, Barbara, Nivarthi, Harini, Schlederer, Michaela, Maurer, Barbara, Hofbauer, Maximillian, Aryee, Dave Nt, Wiedner, Marc, Tomazou, Eleni M, Logan, Malcolm, Hartmann, Christine, Tuckermann, Jan P, Kenner, Lukas, Mikula, Mario, Dolznig, Helmut, Üren, Aykut, Richter, Günther H, Grebien, Florian, Kovar, Heinrich, Moriggl, Richard

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Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation von Javaheri, Tahereh, Kazemi, Zahra, Pencik, Jan, Pham, Ha T. T., Kauer, Maximilian, Noorizadeh, Rahil, Sax, Barbara, Nivarthi, Harini, Schlederer, Michaela, Maurer, Barbara, Hofbauer, Maximillian, Aryee, Dave N. T., Wiedner, Marc, Tomazou, Eleni M., Logan, Malcolm, Hartmann, Christine, Tuckermann, Jan P., Kenner, Lukas, Mikula, Mario, Dolznig, Helmut, Üren, Aykut, Richter, Günther H., Grebien, Florian, Kovar, Heinrich, Moriggl, Richard

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511P Blood biomarkers in a cohort of patients with CHRNE-associated congenital myasthenic syndrome von Della Marina, A., Koutsoulidou, A., Natera de Benito, D., Tykocinski, L., Tomazou, M., Georgiou, K., Kölbel, H., Nascimento, A., Ortez, C., Lochmüller, H., Phylactou, L., Ruck, T., Abicht, A., Schara-Schmidt, U., Kale, D., Hentschel, A., Roos, A.

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Correction: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation von Javaheri, Tahereh, Kazemi, Zahra, Jan Pencik, Pham, Ha T. T., Kauer, Maximilian, Noorizadeh, Rahil, Sax, Barbara, Nivarthi, Harini, Schlederer, Michaela, Maurer, Barbara, Hofbauer, Maximillian, Aryee, Dave N. T., Wiedner, Marc, Tomazou, Eleni M., Logan, Malcolm, Hartmann, Christine, Tuckermann, Jan P., Kenner, Lukas, Mikula, Mario, Dolznig, Helmut, Üren, Aykut, Richter, Günther H., Grebien, Florian, Kovar, Heinrich, Moriggl, Richard

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