Following the design path of isoform-selective Hsp90 inhibitors: Small differences, great opportunities von Dernovšek, Jaka, Tomašič, Tihomir

Volltext

Efflux pump inhibitors of clinically relevant multidrug resistant bacteria von Lamut, Andraž, Peterlin Mašič, Lucija, Kikelj, Danijel, Tomašič, Tihomir

Volltext

Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors von Gjorgjieva, Marina, Tomašič, Tihomir, Barančokova, Michaela, Katsamakas, Sotirios, Ilaš, Janez, Tammela, Päivi, Peterlin Mašič, Lucija, Kikelj, Danijel

Volltext

Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pha... von Šmelcerović, Andrija, Tomović, Katarina, Šmelcerović, Žaklina, Petronijević, Živomir, Kocić, Gordana, Tomašič, Tihomir, Jakopin, Žiga, Anderluh, Marko

Volltext

Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening von Piga, Martina, Varga, Zoltan, Feher, Adam, Papp, Ferenc, Korpos, Eva, Bangera, Kavya C., Frlan, Rok, Ilaš, Janez, Dernovšek, Jaka, Tomašič, Tihomir, Zidar, Nace

Volltext

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2‑d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site von Tomašič, Tihomir, Katsamakas, Sotirios, Hodnik, Žiga, Ilaš, Janez, Brvar, Matjaž, Solmajer, Tom, Montalvão, Sofia, Tammela, Päivi, Banjanac, Mihailo, Ergović, Gabrijela, Anderluh, Marko, Mašič, Lucija Peterlin, Kikelj, Danijel

Volltext

Catalytic performance of Noyori–Ikariya-type ruthenium complex with tethered syn-ULTAM ligand for the asymmetric transfer hydrogenation of ketones von Hašanová, Simona, Cingl, Jernej, Tomašič, Tihomir, Cotman, Andrej Emanuel

Volltext

New Class of Hsp90 C‑Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer von Zajec, Živa, Dernovšek, Jaka, Cingl, Jernej, Ogris, Iza, Gedgaudas, Marius, Zubrienė, Asta, Mitrović, Ana, Golič Grdadolnik, Simona, Gobec, Martina, Tomašič, Tihomir

Volltext

Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory P... von Gobec, Martina, Tomašič, Tihomir, Štimac, Adela, Frkanec, Ruža, Trontelj, Jurij, Anderluh, Marko, Mlinarič-Raščan, Irena, Jakopin, Žiga

Volltext

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa von Cotman, Andrej Emanuel, Durcik, Martina, Benedetto Tiz, Davide, Fulgheri, Federica, Secci, Daniela, Sterle, Maša, Možina, Štefan, Skok, Žiga, Zidar, Nace, Zega, Anamarija, Ilaš, Janez, Peterlin Mašič, Lucija, Tomašič, Tihomir, Hughes, Diarmaid, Huseby, Douglas L., Cao, Sha, Garoff, Linnéa, Berruga Fernández, Talía, Giachou, Paraskevi, Crone, Lisa, Simoff, Ivailo, Svensson, Richard, Birnir, Bryndis, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., de la Cruz, Mercedes, Glinghammar, Björn, Lenhammar, Lena, Henderson, Sara R., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel

Volltext

Last piece in the puzzle of bisphenols BPA, BPS and BPF metabolism: Kinetics of the in vitro sulfation reaction von Durcik, Martina, Gramec Skledar, Darja, Tomašič, Tihomir, Trontelj, Jurij, Peterlin Mašič, Lucija

Volltext

Rational design of balanced dual-targeting antibiotics with limited resistance von Nyerges, Akos, Tomasic, Tihomir, Durcik, Martina, Revesz, Tamas, Szili, Petra, Draskovits, Gabor, Bogar, Ferenc, Skok, Ziga, Zidar, Nace, Ilas, Janez, Zega, Anamarija, Kikelj, Danijel, Daruka, Lejla, Kintses, Balint, Vasarhelyi, Balint, Foldesi, Imre, Kata, Diana, Welin, Martin, Kimbung, Raymond, Focht, Dorota, Masic, Lucija Peterlin, Pal, Csaba

Volltext

Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents von Fedorowicz, Joanna, Sączewski, Jarosław, Konopacka, Agnieszka, Waleron, Krzysztof, Lejnowski, Dawid, Ciura, Krzesimir, Tomašič, Tihomir, Skok, Žiga, Savijoki, Kirsi, Morawska, Małgorzata, Gilbert-Girard, Shella, Fallarero, Adyary

Volltext

Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations von Tomasic, Tihomir, Durcik, Martina, Keegan, Bradley M., Skledar, Darja Gramec, Zajec, Ziva, Blagg, Brian S. J., Bryant, Sharon D.

Volltext

New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus von Durcik, Martina, Cotman, Andrej Emanuel, Toplak, Žan, Možina, Štefan, Skok, Žiga, Szili, Petra Eva, Czikkely, Márton, Maharramov, Elvin, Vu, Thu Hien, Piras, Maria Vittoria, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Trontelj, Jurij, Pardo, Luis A., Hughes, Diarmaid, Huseby, Douglas, Berruga-Fernández, Tália, Cao, Sha, Simoff, Ivailo, Svensson, Richard, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Glinghammar, Björn, Sjöström, Eva, Bohlin, Martin, Oreskär, Joanna, Alvér, Sofie, Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel, Pal, Csaba, Tomašič, Tihomir, Peterlin Mašič, Lucija

Volltext

Galectin-8N-Selective 4‑Halophenylphthalazinone-Galactals Double π‑Stack in a Unique Pocket von van Klaveren, Sjors, Hassan, Mujtaba, Håkansson, Maria, Johnsson, Richard E., Larsson, Jessica, Jakopin, Žiga, Anderluh, Marko, Leffler, Hakon, Tomašič, Tihomir, Nilsson, Ulf J.

Volltext

N‑Phenyl-4,5-dibromopyrrolamides and N‑Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation von Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Solmajer, Tom, Peterlin Mašič, Lucija, Ilaš, Janez, Kikelj, Danijel

Volltext

Virtual Screening Assisted Search for Inhibitors of the Translocated Intimin Receptor of Enteropathogenic Escherichia Coli von Pylkkö, Tuomas, Tomašič, Tihomir, Poso, Antti, Tammela, Päivi

Volltext

Molecular Dynamics-Derived Pharmacophore Model Explaining the Nonselective Aspect of KV10.1 Pore Blockers von Toplak, Zan, Merzel, Franci, Pardo, Luis A., Masic, Lucija Peterlin, Tomasic, Tihomir

Volltext

Optimisation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as novel Hsp90 C-terminal domain inhibitors against Ewing sarcoma von Zajec, Živa, Dernovšek, Jaka, Distel, Martin, Gobec, Martina, Tomašič, Tihomir

Volltext