STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control von Toth, Karoly, Lee, Sang R, Ying, Baoling, Spencer, Jacqueline F, Tollefson, Ann E, Sagartz, John E, Kong, Il-Keun, Wang, Zhongde, Wold, William S M

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Identification of Ebselen derivatives as novel SARS-CoV-2 main protease inhibitors: Design, synthesis, biological evaluation, and structure-activity relationships exploration von Zhang, Heng, Li, Jing, Toth, Karoly, Tollefson, Ann E, Jing, Lanlan, Gao, Shenghua, Liu, Xinyong, Zhan, Peng

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Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV‑2 Main Protease Inhibitors with High Target Specificity and Low Toxicity von Gao, Shenghua, Sylvester, Katharina, Song, Letian, Claff, Tobias, Jing, Lanlan, Woodson, Molly, Weiße, Renato H., Cheng, Yusen, Schäkel, Laura, Petry, Marvin, Gütschow, Michael, Schiedel, Anke C., Sträter, Norbert, Kang, Dongwei, Xu, Shujing, Toth, Karoly, Tavis, John, Tollefson, Ann E., Müller, Christa E., Liu, Xinyong, Zhan, Peng

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NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model von Tollefson, Ann E, Cline-Smith, Anna B, Spencer, Jacqueline F, Reyna, Dawn M, Lipka, Elke, Toth, Karoly

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Filociclovir is a potent inhibitor of human adenovirus F41 von Tollefson, Ann E., Hussein, Islam T.M., Toth, Karoly, Bowlin, Terry L.

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Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV‑2 Main Protease Inhibitors von Gao, Shenghua, Song, Letian, Claff, Tobias, Woodson, Molly, Sylvester, Katharina, Jing, Lanlan, Weiße, Renato H., Cheng, Yusen, Sträter, Norbert, Schäkel, Laura, Gütschow, Michael, Ye, Bing, Yang, Mianling, Zhang, Tao, Kang, Dongwei, Toth, Karoly, Tavis, John, Tollefson, Ann E., Müller, Christa E., Zhan, Peng, Liu, Xinyong

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Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with I... von Gao, Shenghua, Song, Letian, Sylvester, Katharina, Mercorelli, Beatrice, Loregian, Arianna, Toth, Karoly, Weiße, Renato H., Useini, Abibe, Sträter, Norbert, Yang, Mianling, Ye, Bing, Tollefson, Ann E., Müller, Christa E., Liu, Xinyong, Zhan, Peng

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Drug development against human adenoviruses and its advancement by Syrian hamster models von Wold, William S M, Tollefson, Ann E, Ying, Baoling, Spencer, Jacqueline F, Toth, Karoly

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Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model von Tollefson, Ann E, Cline-Smith, Anna, Spencer, Jacqueline F, Ying, Baoling, Reyna, Dawn M, Lipka, Elke, James, Scott H, Toth, Karoly

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Biographical Feature: William S. M. Wold, Ph.D., 1944-2021 von Toth, Karoly, Tollefson, Ann E, Chinnadurai, G, Bellone, Clifford J, Grandgenett, Duane P, Morrison, Lynda A, Tavis, John E

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Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses von Toth, Karoly, Hussein, Islam T M, Tollefson, Ann E, Ying, Baoling, Spencer, Jacqueline F, Eagar, Jessica, James, Scott H, Prichard, Mark N, Wold, William S M, Bowlin, Terry L

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Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovir... von Tollefson, Ann E., Riemann, Samantha B., Ying, Baoling, Spencer, Jacqueline F., Overhulse, Justin M., Kashemirov, Boris A., Wold, William S.M., McKenna, Charles E., Toth, Karoly

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Pathology in Permissive Syrian Hamsters after Infection with Species C Human Adenovirus (HAdV-C) Is the Result of Virus Replication: HAdV-C6 Replicates More and Causes More Patholo... von Tollefson, Ann E, Ying, Baoling, Spencer, Jacqueline F, Sagartz, John E, Wold, William S M, Toth, Karoly

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Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters von Ying, Baoling, Tollefson, Ann E, Spencer, Jacqueline F, Balakrishnan, Lata, Dewhurst, Stephen, Capella, Cristina, Buller, R Mark L, Toth, Karoly, Wold, William S M

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Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening von Jiang, Xiangyi, Li, Jing, Viayna, Antonio, Luque, F Javier, Woodson, Molly, Jing, Lanlan, Gao, Shenghua, Zhao, Fabao, Xie, Minghui, Toth, Karoly, Tavis, John, Tollefson, Ann E, Liu, Xinyong, Zhan, Peng

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Male Syrian hamsters are more susceptible to intravenous infection with species C human adenoviruses than are females von Ying, Baoling, Spencer, Jacqueline F., Tollefson, Ann E., Wold, William S.M., Toth, Karoly

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Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9 von Miao, Jinxin, Ying, Baoling, Li, Rong, Tollefson, Ann E, Spencer, Jacqueline F, Wold, William S M, Song, Seok-Hwan, Kong, Il-Keun, Toth, Karoly, Wang, Yaohe, Wang, Zhongde

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NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin von Lipka, Elke, Chadderdon, Aaron M., Harteg, Cheryl C., Doherty, Matthew K., Simon, Eric S., Domagala, John M., Reyna, Dawn M., Hutchings, Kim M., Gan, Xinmin, White, Andrew D., Hartline, Caroll B., Harden, Emma A., Keith, Kathy A., Prichard, Mark N., James, Scott H., Cardin, Rhonda D., Bernstein, David I., Spencer, Jacqueline F., Tollefson, Ann E., Wold, William S. M., Toth, Karoly

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Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 M pro inhibitors with improved metabolic stability von Gao, Shenghua, Song, Letian, Ye, Bing, Yang, Mianling, Li, Junyi, Gu, Manyu, Tollefson, Ann E, Toth, Karoly, Zhan, Peng, Liu, Xinyong

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Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 Mpro inhibitors with improved metabolic stability von Gao, Shenghua, Song, Letian, Ye, Bing, Yang, Mianling, Li, Junyi, Gu, Manyu, Tollefson, Ann E, Toth, Karoly, Zhan, Peng, Liu, Xinyong

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