793P CHEK2 inactivating germ-line mutations play a role in the development of testicular cancer von Imyanitov, E., Ni, V., Ivantsov, A.O., Kotkova, M., Baskina, S., Ponomareva, E., Shelekhova, K.V., Romanko, A., Aleksakhina, S., Togo, A.V., Sokolenko, A.

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1197P Changes in the concentration of EGFR-mutated (EGFR-M+) plasma DNA in the first hours of TKI therapy allow the prediction of tumour response in patients with EGFR-M+ NSCLC von Kuligina, E.S., Moiseenko, F.V., Belukhin, S.A., Laidus, T.A., Martianov, A.S., Gabina, A.S., Myslik, A.V., Volkov, N.M., Zagorodnev, K.A., Kholmatov, M.M., Sokolova, T.N., Stepanova, M.L., Shuginova, T.N., Togo, A.V., Imyanitov, E.

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PALB2 germ-line mutations in Russian breast cancer patients: Identification of recurrent alleles and analysis of phenotypic characteristics of the tumors von Imyanitov, E.N., Preobrazhenskaya, E.V., Shlejkina, A.Y., Sokolenko, A.P., Anisimova, E.I., Ivantsov, A.O., Togo, A.V.

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Lung cancers carrying distinct ALK fusion variants demonstrate similar responsiveness to ALK tyrosine kinase inhibitors von Imyanitov, E.N., Mitiushkina, N.V., Tiurin, V.I., Iyevleva, A.G., Holmatov, M., Filippova, E., Moiseyenko, F., Levchenko, N., Odintsova, S., Lozhkina, A., Togo, A.V., Karaseva, N., Moiseyenko, V.M., Orlov, S.

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Improved Reliability of Allele-Specific PCR von Imyanitov, E.N, Buslov, K.G, Suspitsin, E.N, Kuligina, E.Sh, Belogubova, E.V, Grigoriev, M.Yu, Togo, A.V, Hanson, K.P

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Partial Restoration of Degraded DNA from Archival Paraffin-Embedded Tissues von Imyanitov, E.N, Grigoriev, M.Yu, Gorodinskaya, V.M, Kuligina, E.Sh, Pozharisski, K.M, Togo, A.V, Hanson, K.P

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Spectrum of APC and MUTYH germ‐line mutations in Russian patients with colorectal malignancies von Yanus, G.A., Akhapkina, T.A., Ivantsov, A.O., Preobrazhenskaya, E.V., Aleksakhina, S.N., Bizin, I.V., Sokolenko, A.P., Mitiushkina, N.V., Kuligina, E.Sh, Suspitsin, E.N., Venina, A.R., Holmatov, M.M., Zaitseva, O.A., Yatsuk, O.S., Pashkov, D.V., Belyaev, A.M., Togo, A.V., Imyanitov, E.N., Iyevleva, A.G.

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Improved Reliability of Allele-Specific PCR von Imyanitov, E.N, Buslov, K.G, Suspitsin, E.N, Kuligina, E.Sh, Belogubova, E.V, Grigoriev, M.Yu, Togo, A.V, Hanson, K.P

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558 POSTER Measurement of DPD and TS transcripts aimed to predict clinical benefit from fluoropyrimidines: confirmation of the trend in Russian colorectal cancer series and caution... von Suspitsin, E.N, Iyevleva, A.G, Buslov, K.G, Erofeev, A.F, Togo, A.V, Matsko, D.E, Filimonenko, V.P, Prochukhanov, A.R, Moiseenko, V.M, Imyanitov, E.N

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Distinct prevalence of the CYP19 Δ3(TTTA) 7 allele in premenopausal versus postmenopausal breast cancer patients, but not in control individuals von Suspitsin, E.N., Grigoriev, M.Y., Togo, A.V., Kuligina, E.S., Belogubova, E.V., Pozharisski, K.M., Chagunava, O.L., Sokolov, E.P., Theillet, C., Berstein, L.M., Hanson, K.P., Imyanitov, E.N.

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Hereditary breast-ovarian cancer syndrome in Russia von Sokolenko, A P, Iyevleva, A G, Mitiushkina, N V, Suspitsin, E N, Preobrazhenskaya, E V, Kuligina, E Sh, Voskresenskiy, D A, Lobeiko, O S, Krylova, N Yu, Gorodnova, T V, Buslov, K G, Bit-Sava, E M, Dolmatov, G D, Porhanova, N V, Polyakov, I S, Abysheva, S N, Katanugina, A S, Baholdin, D V, Yanus, G A, Togo, A V, Moiseyenko, V M, Maximov, S Ya, Semiglazov, V F, Imyanitov, E N

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1043 Reassessment of GSTM1 and GSTT1 cancer predisposing roles: comparison of genotypes in elderly tumor-free smokers and non-smokers vs. healthy donors vs. lung cancer patients von Togo, A.V., Belogubova, E., Karpova, M., Ulibina, J., Buslov, K., Lemehov, V., Shutkin, V., Hanson, K., Hirvonen, A., Imyanitov, E.

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Amplification of ERBB-2 (HER-2JNEU) oncogene as a potential prognostic marker for breast but not ovarian cancer in Russian group of patient von Imyanitov, E.N., Chemitsa, O.I., Serova, O.M., Nikiforova, I.F., Togo, A.V., Knyazev, P.G., Hanson, K.P.

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Amplification of ERBB-2 (HER-2/NEU), ERBB-1 (HER-1) and C-MYC oncogenes often combines with the deletion of chromosome 17 short arm in human carcinomas von Hanson, K.P., Imynitov, E.N., Chemitsa, O.I., Nikiforova, I.F., Laur, O.Y., Knyazev, P.G., Togo, A.V.

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Distribution of HLA-DRB alleles in breast cancer patients differs from this one in healthy donors von Togo, A.V., Imyanitov, E.N., Komochkov, I.V., Chernitsa, O.I., Knyazev, P.G., Lyschov, A.A.

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Allelic distribution of DRB locus of II class major histocompatibility complex genes is associated with tumour size, nodal involvement, stage of disease and age of patients in brea... von Knyazev, P.G., Lyshchov, A.A., Imyanitov, E.N., Romochkov, I.V., Chernitsa, O.I., Togo, A.V.

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METHOD FOR IDENTIFYING GENE MUTATION AND POLYMORPHISM von IMJANITOV E.N, BUSLOV K.G, BELOGUBOVA E.V, KULIGINA E.SH, KHANSON K.P, SUSPITSYN E.N, GRIGOR'EV M.JU, TOGO A.V

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METHOD FOR DNA RECOVERY ISOLATED FROM ARCHIVES PATHOMORPHOLOGICAL TISSUE SAMPLES von IMJANITOV E.N, GORODINSKAJA V.M, KHANSON K.P, GRIGOR'EV M.JU, SUSPITSYN E.N, TOGO A.V

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Vascular system anatomy of the anterolateral thigh flap von Karpenko, A.V., Sibgatullin, R.R., Boyko, A.A., Kostova, M.G., Nikolaeva, O.M., Togo, I.A.

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