Initiation and progression of α-synuclein pathology in Parkinson’s disease von Tofaris, George K.

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Lysosome-dependent pathways as a unifying theme in Parkinson's disease von Tofaris, George K.

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How is alpha‐synuclein cleared from the cell? von Stefanis, Leonidas, Emmanouilidou, Evangelia, Pantazopoulou, Marina, Kirik, Deniz, Vekrellis, Kostas, Tofaris, George K.

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Facile Impedimetric Analysis of Neuronal Exosome Markers in Parkinson's Disease Diagnostics von Fu, Ying, Jiang, Cheng, Tofaris, George K, Davis, Jason J

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Concentration-Normalized Electroanalytical Assaying of Exosomal Markers von Li, Qian, Tofaris, George K, Davis, Jason J

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ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons von Fernandes, Hugo J.R., Hartfield, Elizabeth M., Christian, Helen C., Emmanoulidou, Evangelia, Zheng, Ying, Booth, Heather, Bogetofte, Helle, Lang, Charmaine, Ryan, Brent J., Sardi, S. Pablo, Badger, Jennifer, Vowles, Jane, Evetts, Samuel, Tofaris, George K., Vekrellis, Kostas, Talbot, Kevin, Hu, Michele T., James, William, Cowley, Sally A., Wade-Martins, Richard

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Methodological considerations in neuronal extracellular vesicle isolation for α-synuclein biomarkers von Yan, Shijun, Jiang, Cheng, Davis, Jason J, Tofaris, George K

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Alternating Magnetic Field-Promoted Nanoparticle Mixing: The On-Chip Immunocapture of Serum Neuronal Exosomes for Parkinson’s Disease Diagnostics von Sharafeldin, Mohamed, Yan, Shijun, Jiang, Cheng, Tofaris, George K., Davis, Jason J.

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Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons von Tanudjojo, Benedict, Shaikh, Samiha S., Fenyi, Alexis, Bousset, Luc, Agarwal, Devika, Marsh, Jade, Zois, Christos, Heman-Ackah, Sabrina, Fischer, Roman, Sims, David, Melki, Ronald, Tofaris, George K.

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Validation of α‐Synuclein in L1CAM‐Immunocaptured Exosomes as a Biomarker for the Stratification of Parkinsonian Syndromes von Jiang, Cheng, Hopfner, Franziska, Berg, Daniela, Hu, Michele T., Pilotto, Andrea, Borroni, Barbara, Davis, Jason J., Tofaris, George K.

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Multiplexed Profiling of Extracellular Vesicles for Biomarker Development von Jiang, Cheng, Fu, Ying, Liu, Guozhen, Shu, Bowen, Davis, Jason, Tofaris, George K.

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The endosomal pathway in Parkinson's disease von Perrett, Rebecca M., Alexopoulou, Zoi, Tofaris, George K.

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Ubiquitin ligase Nedd4 promotes α-synuclein degradation by the endosomal–lysosomal pathway von Tofaris, George K, Kim, Hyoung Tae, Hourez, Raphael, Jung, Jin-Woo, Kim, Kwang Pyo, Goldberg, Alfred L

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Dopamine enhances willingness to exert effort for reward in Parkinson's disease von Chong, Trevor T.-J., Bonnelle, Valerie, Manohar, Sanjay, Veromann, Kai-Riin, Muhammed, Kinan, Tofaris, George K., Hu, Michele, Husain, Masud

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Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease von Davies, Sian E, Hallett, Penelope J, Moens, Thomas, Smith, Gaynor, Mangano, Emily, Kim, Hyoung Tae, Goldberg, Alfred L, Liu, Ji-Long, Isacson, Ole, Tofaris, George K

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Neuronally Derived Extracellular Vesicle α-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease von Yan, Shijun, Jiang, Cheng, Janzen, Annette, Barber, Thomas R, Seger, Aline, Sommerauer, Michael, Davis, Jason J, Marek, Kenneth, Hu, Michele T, Oertel, Wolfgang H, Tofaris, George K

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SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease von Garcia-Reitböck, Pablo, Anichtchik, Oleg, Bellucci, Arianna, Iovino, Mariangela, Ballini, Chiara, Fineberg, Elena, Ghetti, Bernardino, Della Corte, Laura, Spano, PierFranco, Tofaris, George K., Goedert, Michel, Spillantini, Maria Grazia

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Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra von Garcia-Reitboeck, Pablo, Anichtchik, Oleg, Dalley, Jeffrey W., Ninkina, Natalia, Tofaris, George K., Buchman, Vladimir L., Spillantini, Maria Grazia

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Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease von Alexopoulou, Zoi, Lang, Johannes, Perrett, Rebecca M., Elschami, Myriam, Hurry, Madeleine E. D., Kim, Hyoung Tae, Mazaraki, Dimitra, Szabo, Aron, Kessler, Benedikt M., Goldberg, Alfred Lewis, Ansorge, Olaf, Fulga, Tudor A., Tofaris, George K.

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The Transcellular Propagation and Intracellular Trafficking of α-Synuclein von Tofaris, George K, Goedert, Michel, Spillantini, Maria Grazia

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