Micro biochemical engineering to accelerate the design of industrial-scale downstream processes for biopharmaceutical proteins von Titchener-Hooker, N.J, Dunnill, P, Hoare, M

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Scale-down prediction of industrial scale pleated membrane cartridge performance von Brown, A.I., Titchener-Hooker, N.J., Lye, G.J.

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Economic comparison between conventional and disposables-based technology for the production of biopharmaceuticals von Novais, J. L., Titchener-Hooker, N. J., Hoare, M.

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Principal Component Score Modeling for the Rapid Description of Chromatographic Separations von Edwards-Parton, S., Thornhill, N. F., Bracewell, D. G., Liddell, J. M., Titchener-Hooker, N. J.

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Experimental measurement of particle size distribution and voidage in an expanded bed adsorption system von Willoughby, N. A., Hjorth, R., Titchener-Hooker, N. J.

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Visualizing integrated bioprocess designs through "windows of operation" von Zhou, Y. H., Titchener-Hooker, N. J.

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Hydrophobic interaction ligand selection and scale-up of an expanded bed separation of an intracellular enzyme from Saccharomyces cerevisiae von Smith, M.P, Bulmer, M.A, Hjorth, R, Titchener-Hooker, N.J

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Prediction of the pilot-scale recovery of a recombinant yeast enzyme using integrated models von Varga, E. G., Titchener-Hooker, N. J., Dunnill, P.

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Degradation of supercoiled plasmid DNA within a capillary device von Meacle, F.J., Zhang, H., Papantoniou, I., Ward, J.M., Titchener-Hooker, N.J., Hoare, M.

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Time Course of SDS–alkaline lysis of recombinant bacterial cells for plasmid release von Ciccolini, L. A. S., Shamlou, P. Ayazi, Titchener‐Hooker, N. J., Ward, J. M., Dunnill, P.

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Use of PAT principles for the open-loop control of laboratory and pilot-scale chromatography columns von Chhatre, S, Bou-Habib, G, Smith, M.P, Hoare, M, Bracewell, D.G, Titchener-Hooker, N.J

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The use of rapid on-line monitoring of products and contaminants from within an expanded bed to control separations exhibiting fast breakthrough characteristics and to maximize pro... von Willoughby, N., Habib, G., Hoare, M., Hjorth, R., Titchener-Hooker, N. J.

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Impact of engineering flow conditions on plasmid DNA yield and purity in chemical cell lysis operations von Meacle, F.J., Lander, R., Ayazi Shamlou, P., Titchener-Hooker, N.J.

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Immobilised metal ion affinity chromatography purification of alcohol dehydrogenase from baker’s yeast using an expanded bed adsorption system von Willoughby, N.A., Kirschner, T., Smith, M.P., Hjorth, R., Titchener-Hooker, N.J.

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Graphical method for the calculation of chromatographic performance in representing the trade-off between purity and recovery von Ngiam, S.H., Zhou, Y.H., Turner, M.K., Titchener-Hooker, N.J.

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Decision-Support Tool for Assessing Biomanufacturing Strategies under Uncertainty: Stainless Steel versus Disposable Equipment for Clinical Trial Material Preparation von Farid, Suzanne S., Washbrook, John, Titchener-Hooker, Nigel J.

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Ranking bioprocess variables using global sensitivity analysis : a case study in centrifugation von KING, J. M. P, TITCHENER-HOOKER, N. J, ZHOU, Y

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Use of At-Line Spectrophotometry for the Rapid Definition of Pilot-Scale Flocculation Processes von Bou-Habib, G., Yeung, K., Titchener-Hooker, N. J., Hoare, M.

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A decision-support model for evaluating changes in biopharmaceutical manufacturing processes von CHHATRE, S, FRANCIS, R, O'DONOVAN, K, TITCHENER-HOOKER, N. J, NEWCOMBE, A. R, KESHAVARZ-MOORE, E

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Simulation of particle size distribution changes occurring during high-pressure disruption of bakers' yeast von Siddiqi, S. F., Titchener-Hooker, N. J., Shamlou, P. Ayazi

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