A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation von Pan, Jing, Sasaki, Mariko, Kniewel, Ryan, Murakami, Hajime, Blitzblau, Hannah G., Tischfield, Sam E., Zhu, Xuan, Neale, Matthew J., Jasin, Maria, Socci, Nicholas D., Hochwagen, Andreas, Keeney, Scott

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The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair von Lange, Julian, Yamada, Shintaro, Tischfield, Sam E., Pan, Jing, Kim, Seoyoung, Zhu, Xuan, Socci, Nicholas D., Jasin, Maria, Keeney, Scott

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Structural and functional characterization of the Spo11 core complex von Claeys Bouuaert, Corentin, Tischfield, Sam E., Pu, Stephen, Mimitou, Eleni P., Arias-Palomo, Ernesto, Berger, James M., Keeney, Scott

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Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts von Caeser, Rebecca, Egger, Jacklynn V., Chavan, Shweta, Socci, Nicholas D., Jones, Caitlin Byrne, Kombak, Faruk Erdem, Asher, Marina, Roehrl, Michael H., Shah, Nisargbhai S., Allaj, Viola, Manoj, Parvathy, Tischfield, Sam E., Kulick, Amanda, Meneses, Maximiliano, Iacobuzio-Donahue, Christine A., Lai, W. Victoria, Bhanot, Umeshkumar, Baine, Marina K., Rekhtman, Natasha, Hollmann, Travis J., de Stanchina, Elisa, Poirier, John T., Rudin, Charles M., Sen, Triparna

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Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation von Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Zhan, Yingqian A., Hasan, Maysun M., Chavan, Shweta S., Meng, Fanli, Uddin, Fathema, Manoj, Parvathy, Donoghue, Mark T. A., Won, Helen H., Chan, Joseph M., Ciampricotti, Metamia, Chow, Andrew, Offin, Michael, Chang, Jason C., Ray-Kirton, Jordana, Tischfield, Sam E., Egger, Jacklynn, Bhanot, Umesh K., Linkov, Irina, Asher, Marina, Sinha, Sonali, Silber, Joachim, Iacobuzio-Donahue, Christine A., Roehrl, Michael H., Hollmann, Travis J., Yu, Helena A., Qiu, Juan, de Stanchina, Elisa, Baine, Marina K., Rekhtman, Natasha, Poirier, John T., Loomis, Brian, Koche, Richard P., Rudin, Charles M., Sen, Triparna

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Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice von Yamada, Shintaro, Kim, Seoyoung, Tischfield, Sam E., Jasin, Maria, Lange, Julian, Keeney, Scott

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Scale matters: The spatial correlation of yeast meiotic DNA breaks with histone H3 trimethylation is driven largely by independent colocalization at promoters von Tischfield, Sam E., Keeney, Scott

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Meiotic recombination initiation in and around retrotransposable elements in Saccharomyces cerevisiae von Sasaki, Mariko, Tischfield, Sam E, van Overbeek, Megan, Keeney, Scott

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Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library von Offin, Michael, Sauter, Jennifer L, Tischfield, Sam E, Egger, Jacklynn V, Chavan, Shweta, Shah, Nisargbhai S, Manoj, Parvathy, Ventura, Katia, Allaj, Viola, de Stanchina, Elisa, Travis, William, Ladanyi, Marc, Rimner, Andreas, Rusch, Valerie W, Adusumilli, Prasad S, Poirier, John T, Zauderer, Marjorie G, Rudin, Charles M, Sen, Triparna

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The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer von Chow, Andrew, Uddin, Fathema Z., Liu, Michael, Dobrin, Anton, Nabet, Barzin Y., Mangarin, Levi, Lavin, Yonit, Rizvi, Hira, Tischfield, Sam E., Quintanal-Villalonga, Alvaro, Chan, Joseph M., Shah, Nisargbhai, Allaj, Viola, Manoj, Parvathy, Mattar, Marissa, Meneses, Maximiliano, Landau, Rebecca, Ward, Mariana, Kulick, Amanda, Kwong, Charlene, Wierzbicki, Matthew, Yavner, Jessica, Egger, Jacklynn, Chavan, Shweta S., Farillas, Abigail, Holland, Aliya, Sridhar, Harsha, Ciampricotti, Metamia, Hirschhorn, Daniel, Guan, Xiangnan, Richards, Allison L., Heller, Glenn, Mansilla-Soto, Jorge, Sadelain, Michel, Klebanoff, Christopher A., Hellmann, Matthew D., Sen, Triparna, de Stanchina, Elisa, Wolchok, Jedd D., Merghoub, Taha, Rudin, Charles M.

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Developmental chromatin programs determine oncogenic competence in melanoma von Baggiolini, Arianna, Callahan, Scott J., Montal, Emily, Weiss, Joshua M., Trieu, Tuan, Tagore, Mohita M., Tischfield, Sam E., Walsh, Ryan M., Suresh, Shruthy, Fan, Yujie, Campbell, Nathaniel R., Perlee, Sarah C., Saurat, Nathalie, Hunter, Miranda, Simon-Vermot, Theresa, Huang, Ting-Hsiang, Ma, Yilun, Hollmann, Travis, Tickoo, Satish K., Taylor, Barry S., Khurana, Ekta, Koche, Richard P., Studer, Lorenz, White, Richard M.

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MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer von Caeser, Rebecca, Hulton, Christopher, Costa, Emily, Durani, Vidushi, Little, Megan, Chen, Xiaoping, Tischfield, Sam E., Asher, Marina, Kombak, Faruk Erdem, Chavan, Shweta S., Shah, Nisargbhai S., Ciampricotti, Metamia, de Stanchina, Elisa, Poirier, John T., Rudin, Charles M., Sen, Triparna

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Combination Therapy With MDM2 and MEK Inhibitors Is Effective in Patient-Derived Models of Lung Adenocarcinoma With Concurrent Oncogenic Drivers and MDM2 Amplification von Elkrief, Arielle, Odintsov, Igor, Markov, Vladimir, Caeser, Rebecca, Sobczuk, Pawel, Tischfield, Sam E., Bhanot, Umesh, Vanderbilt, Chad M., Cheng, Emily H., Drilon, Alexander, Riely, Gregory J., Lockwood, William W., de Stanchina, Elisa, Tirunagaru, Vijaya G., Doebele, Robert C., Quintanal-Villalonga, Álvaro, Rudin, Charles M., Somwar, Romel, Ladanyi, Marc

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ATR inhibition activates cancer cell cGAS/STING-interferon signaling and promotes antitumor immunity in small-cell lung cancer von Taniguchi, Hirokazu, Chakraborty, Subhamoy, Takahashi, Nobuyuki, Banerjee, Avisek, Caeser, Rebecca, Zhan, Yingqian A, Tischfield, Sam E, Chow, Andrew, Nguyen, Evelyn M, Villalonga, Álvaro Quintanal, Manoj, Parvathy, Shah, Nisargbhai S, Rosario, Samantha, Hayatt, Omar, Qu, Rui, de Stanchina, Elisa, Chan, Joseph, Mukae, Hiroshi, Thomas, Anish, Rudin, Charles M, Sen, Triparna

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Article MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer von Caeser, Rebecca, Hulton, Christopher, Costa, Emily, Durani, Vidushi, Little, Megan, Chen, Xiaoping, Tischfield, Sam E., Asher, Marina, Kombak, Faruk Erdem, Chavan, Shweta S., Shah, Nisargbhai S., Ciampricotti, Metamia, de Stanchina, Elisa, Poirier, John T., Rudin, Charles M., Sen, Triparna

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Meiotic Recombination Initiation in and around Retrotransposable Elements in Saccharomyces cerevisiae: e1003732 von Sasaki, Mariko, Tischfield, Sam E, Overbeek, Megan van, Keeney, Scott

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Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation von Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Zhan, Yingqian A., Hasan, Maysun M., Chavan, Shweta S., Meng, Fanli, Uddin, Fathema, Manoj, Parvathy, Donoghue, Mark T.A., Won, Helen H., Chan, Joseph M., Ciampricotti, Metamia, Chow, Andrew, Offin, Michael, Chang, Jason C., Ray-Kirton, Jordana, Tischfield, Sam E., Egger, Jacklynn, Bhanot, Umesh K., Linkov, Irina, Asher, Marina, Sinha, Sonali, Silber, Joachim, Iacobuzio-Donahue, Christine A., Roehrl, Michael H., Hollmann, Travis J., Yu, Helena A., Qiu, Juan, de Stanchina, Elisa, Baine, Marina K., Rekhtman, Natasha, Poirier, John T., Loomis, Brian, Koche, Richard P., Rudin, Charles M., Sen, Triparna

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Abstract 3858: Exploring Exportin-1 as a therapeutic vulnerability in squamous cell carcinoma von Durani, Vidushi, Caeser, Rebecca, Rudin, Charles M., Quintanal-Villalonga, Alvaro, Sridhar, Harsha, Manoj, Parvathy, Tischfield, Sam E., Asher, Marina, Bhanot, Umeshkumar, Egger, Jacklynn V., Socci, Nicholas D. Socci D., Shah, Nisargbhai S S., de Stanchina, Elisa, Rekhtman, Natasha

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Abstract 90: STAT3-driven MAPK activation represents a therapeutic vulnerability in ASCL1 high SCLC von Caeser, Rebecca, Hulton, Christopher, Costa, Emily, Durani, Vidushi, Little, Megan, Chen, Xiaoping, Tischfield, Sam E., Asher, Marina, Kombak, Faruk Erdem, Chavan, Shweta S., Shah, Nisargbhai S., Ciampricotti, Metamia, de Stanchina, Elisa, Poirier, John T., Rudin, Charles M., Sen, Triparna

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Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice von Yamada, Shintaro, Seoyoung Kim, Tischfield, Sam E., Jasin, Maria, Lange, Julian, Keeney, Scott

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