Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse von Tinsley, Jonathon M, Fairclough, Rebecca J, Storer, Richard, Wilkes, Fraser J, Potter, Allyson C, Squire, Sarah E, Powell, Dave S, Cozzoli, Anna, Capogrosso, Roberta F, Lambert, Adam, Wilson, Francis X, Wren, Stephen P, De Luca, Annamaria, Davies, Kay E

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Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model von Babbs, Arran, Berg, Adam, Chatzopoulou, Maria, Davies, Kay E., Davies, Stephen G., Edwards, Benjamin, Elsey, David J., Emer, Enrico, Figuccia, Aude L.A., Fletcher, Ai M., Guiraud, Simon, Harriman, Shawn, Moir, Lee, Robinson, Neil, Rowley, Jessica A., Russell, Angela J., Squire, Sarah E., Thomson, James E., Tinsley, Jonathon M., Wilson, Francis X., Wynne, Graham M.

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Discovery of 2-Arylbenzoxazoles as Upregulators of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy von Chancellor, Daniel R, Davies, Kay E, De Moor, Olivier, Dorgan, Colin R, Johnson, Peter D, Lambert, Adam G, Lawrence, Daniel, Lecci, Cristina, Maillol, Carole, Middleton, Penny J, Nugent, Gary, Poignant, Séverine D, Potter, Allyson C, Price, Paul D, Pye, Richard J, Storer, Richard, Tinsley, Jonathon M, van Well, Renate, Vickers, Richard, Vile, Julia, Wilkes, Fraser J, Wilson, Francis X, Wren, Stephen P, Wynne, Graham M

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Utrophin-Dystrophin-Deficient Mice as a Model for Duchenne Muscular Dystrophy von Deconinck, Anne E, Rafael, Jill A, Skinner, Judith A, Brown, Susan C, Potter, Allyson C, Metzinger, Laurent, Watt, Diana J, Dickson, J.George, Tinsley, Jonathon M, Davies, Kay E

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Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene von Tinsley, Jonathon M., Potter, Allyson C., Phelps, Steven R., Fisher, Rosie, Trickett, Jeffrey I., Davies, Kay E.

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2‑Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy von Babbs, Arran, Berg, Adam, Chatzopoulou, Maria, Davies, Kay E, Davies, Stephen G, Edwards, Benjamin, Elsey, David J, Emer, Enrico, Guiraud, Simon, Harriman, Shawn, Lecci, Cristina, Moir, Lee, Peters, David, Robinson, Neil, Rowley, Jessica A, Russell, Angela J, Squire, Sarah E, Tinsley, Jonathon M, Wilson, Francis X, Wynne, Graham M

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Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid von Chatzopoulou, Maria, Claridge, Tim D. W, Davies, Kay E, Davies, Stephen G, Elsey, David J, Emer, Enrico, Fletcher, Ai M, Harriman, Shawn, Robinson, Neil, Rowley, Jessica A, Russell, Angela J, Tinsley, Jonathon M, Weaver, Richard, Wilkinson, Isabel V. L, Willis, Nicky J, Wilson, Francis X, Wynne, Graham M

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Postsynaptic Abnormalities at the Neuromuscular Junctions of Utrophin-Deficient Mice von Deconinck, Anne E., Potter, Allyson C., Tinsley, Jonathon M., Wood, Sarah J., Vater, Ruth, Young, Carol, Metzinger, Laurent, Vincent, Angela, Slater, Clarke R., Davies, Kay E.

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A Second Promoter Provides an Alternative Target for Therapeutic up-Regulation of Utrophin in Duchenne Muscular Dystrophy von Burton, Edward A., Tinsley, Jonathon M., Holzfeind, Paul J., Rodrigues, Nanda R., Davies, Kay E.

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Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy von De Moor, Olivier, Dorgan, Colin R., Johnson, Peter D., Lambert, Adam G., Lecci, Cristina, Maillol, Carole, Nugent, Gary, Poignant, Séverine D., Price, Paul D., Pye, Richard J., Storer, Richard, Tinsley, Jonathon M., Vickers, Richard, Well, Renate van, Wilkes, Fraser J., Wilson, Francis X., Wren, Stephen P., Wynne, Graham M.

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Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice von Rafael, Jill A., Tinsley, Jonathon M., Potter, Allyson C., Deconinck, Anne E., Davies, Kay E.

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Induction of Utrophin Gene Expression by Heregulin in Skeletal Muscle Cells: Role of the N-Box Motif and GA Binding Protein von Gramolini, Anthony O., Angus, Lindsay M., Schaeffer, Laurent, Burton, Edward A., Tinsley, Jonathon M., Davies, Kay E., Changeux, Jean-Pierre, Jasmin, Bernard J.

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Direct interaction of Smn with dp103, a putative RNA helicase : a role for Smn in transcription regulation? von CAMPBELL, L, HUNTER, K. M. D, MOHAGHEGH, P, TINSLEY, J. M, BRASCH, M. A, DAVIES, K. E

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Increasing Complexity of the Dystrophin-Associated Protein Complex von Tinsley, Jonathon M., Blake, Derek J., Zuellig, Richard A., Davies, Kay E.

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Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles von GILBERT, R, NALBANTOGLU, J, PETROF, B. J, EBIHARA, S, GUIBINGA, G.-H, TINSLEY, J. M, KAMEN, A, MASSIE, B, DAVIES, K. E, KARPATI, G

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Non-toxic ubiquitous over-expression of utrophin in the mdx mouse von Fisher, Rosie, Tinsley, Jonathon M, Phelps, Steve R, Squire, Sarah E, Townsend, Elizabeth R, Martin, Jo E, Davies, Kay E

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Muscle and Neural Isoforms of Agrin Increase Utrophin Expression in Cultured Myotubes via a Transcriptional Regulatory Mechanism von Gramolini, Anthony O., Burton, Edward A., Tinsley, Jonathon M., Ferns, Michael J., Cartaud, Annie, Cartaud, Jean, Davies, Kay E., Lunde, John A., Jasmin, Bernard J.

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Local Transcriptional Control of Utrophin Expression at the Neuromuscular Synapse von Gramolini, Anthony O., Dennis, Carina L., Tinsley, Jonathon M., Robertson, George S., Cartaud, Jean, Davies, Kay E., Jasmin, Bernard J.

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Efficient Utrophin Expression Following Adenovirus Gene Transfer in Dystrophic Muscle von Gilbert, Rénald, Nalbanoglu, Josephine, Tinsley, Jonathon M., Massie, Bernard, Davies, Kay E., Karpati, George

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Apo-dystrophin-3: a 2.2kb transcript from the DMD locus encoding the dystrophin glycoprotein binding site von Tinsley, Jonathon M., Blake, Derek J., Davies, Kay E.

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