Neural Stem Cell-Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients von Portnow, Jana, Synold, Timothy W, Badie, Behnam, Tirughana, Revathiswari, Lacey, Simon F, D'Apuzzo, Massimo, Metz, Marianne Z, Najbauer, Joseph, Bedell, Victoria, Vo, Tien, Gutova, Margarita, Frankel, Paul, Chen, Mike, Aboody, Karen S

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In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model von Threatt, Stephanie D., Synold, Timothy W., Wu, Jun, Barton, Jacqueline K.

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The Neuropharmacokinetics of Temozolomide in Patients with Resectable Brain Tumors: Potential Implications for the Current Approach to Chemoradiation von Portnow, Jana, Badie, Behnam, Chen, Mike, Liu, An, Blanchard, Suzette, Synold, Timothy W

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HIV Replication and Latency in a Humanized NSG Mouse Model during Suppressive Oral Combinational Antiretroviral Therapy von Satheesan, Sangeetha, Li, Haitang, Burnett, John C., Takahashi, Mayumi, Li, Shasha, Wu, Shiny Xiaqin, Synold, Timothy W., Rossi, John J., Zhou, Jiehua

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Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma von Brown, Christine E, Rodriguez, Analiz, Palmer, Joycelynne, Ostberg, Julie R, Naranjo, Araceli, Wagner, Jamie R, Aguilar, Brenda, Starr, Renate, Weng, Lihong, Synold, Timothy W, Tran, Vivi, Wang, Shelley, Reik, Andreas, D’Apuzzo, Massimo, Ressler, Julie A, Zhou, Yuanyue, Mendel, Matthew, Gregory, Philip D, Holmes, Michael C, Tang, Winson W, Forman, Stephen J, Jensen, Michael C, Badie, Behnam

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Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma von Chen, Robert, Herrera, Alex F, Hou, Jessie, Chen, Lu, Wu, Jun, Guo, Yuming, Synold, Timothy W, Ngo, Vu N, Puverel, Sandrine, Mei, Matthew, Popplewell, Leslie, Yi, Shuhua, Song, Joo Y, Tao, Shu, Wu, Xiwei, Chan, Wing C, Forman, Stephen J, Kwak, Larry W, Rosen, Steven T, Newman, Edward M

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An LC–MS/MS method for determination of the bromodomain inhibitor ZEN-3694 and its metabolite ZEN-3791 in human plasma von Feng, Ye, Mahdi, Haider, Piekarz, Richard, Beumer, Jan H, Synold, Timothy W

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Small molecule targeting of transcription-replication conflict for selective chemotherapy von Gu, Long, Li, Min, Li, Caroline M., Haratipour, Pouya, Lingeman, Robert, Jossart, Jennifer, Gutova, Margarita, Flores, Linda, Hyde, Caitlyn, Kenjić, Nikola, Li, Haiqing, Chung, Vincent, Li, Hongzhi, Lomenick, Brett, Von Hoff, Daniel D., Synold, Timothy W., Aboody, Karen S., Liu, Yilun, Horne, David, Hickey, Robert J., Perry, J. Jefferson P., Malkas, Linda H.

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux von Forman, Barry Marc, Synold, Timothy W, Dussault, Isabelle

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Adjuvant everolimus after surgery for renal cell carcinoma (EVEREST): a double-blind, placebo-controlled, randomised, phase 3 trial von Ryan, Christopher W, Tangen, Catherine M, Heath, Elisabeth I, Stein, Mark N, Meng, Maxwell V, Alva, Ajjai S, Pal, Sumanta K, Puzanov, Igor, Clark, Joseph I, Choueiri, Toni K, Agarwal, Neeraj, Uzzo, Robert G, Haas, Naomi B, Synold, Timothy W, Plets, Melissa, Vaishampayan, Ulka N, Shuch, Brian M, Thompson, Ian M, Lara, Primo N

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A phase 1 trial of 8‐chloro‐adenosine in relapsed/refractory acute myeloid leukemia: An evaluation of safety and pharmacokinetics von Pullarkat, Vinod, Chen, Lisa S., Palmer, Joycelynne, Zhang, Jianying, Synold, Timothy W., Buettner, Ralf, Truong Nguyen, Le Xuan, Marcucci, Guido, Tsai, Ni‐Chun, Wang, Yan, O’Hearn, James, Gandhi, Varsha, Rosen, Steven T.

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A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance von BINGSEN ZHOU, LEILA SU, HORNE, David, YUN YEN, SHUYA HU, WEIDONG HU, YIP, M. L. Richard, JUN WU, GAUR, Shikha, LYNNE SMITH, D, YUAN, Yate-Ching, SYNOLD, Timothy W

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Cell facilitation promotes growth and survival under drug pressure in breast cancer von Emond, Rena, Griffiths, Jason I., Grolmusz, Vince Kornél, Nath, Aritro, Chen, Jinfeng, Medina, Eric F., Sousa, Rachel S., Synold, Timothy, Adler, Frederick R., Bild, Andrea H.

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Quantitative Evaluation of Intraventricular Delivery of Therapeutic Neural Stem Cells to Orthotopic Glioma von Gutova, Margarita, Flores, Linda, Adhikarla, Vikram, Tsaturyan, Lusine, Tirughana, Revathiswari, Aramburo, Soraya, Metz, Marianne, Gonzaga, Joanna, Annala, Alexander, Synold, Timothy W, Portnow, Jana, Rockne, Russell C, Aboody, Karen S

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Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon... von Doroshow, James H., Gaur, Shikha, Markel, Susan, Lu, Jiamo, van Balgooy, Josephus, Synold, Timothy W., Xi, Bixin, Wu, Xiwei, Juhasz, Agnes

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Adjuvant Everolimus in Patients with Completely Resected, Very High-risk Renal Cell Carcinoma of Clear Cell Histology: Results from the Phase 3 Placebo-controlled SWOG S0931 (EVERE... von Lara, Primo N., Tangen, Catherine, Heath, Elisabeth I., Gulati, Shuchi, Stein, Mark N., Meng, Maxwell, Alva, Ajjai Shivaram, Pal, Sumanta K., Puzanov, Igor, Clark, Joseph I., Choueiri, Toni K., Agarwal, Neeraj, Uzzo, Robert, Haas, Naomi B., Synold, Timothy W., Plets, Melissa, Vaishampayan, Ulka N., Shuch, Brian M., Lerner, Seth, Thompson, Ian M., Ryan, Christopher W.

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An LC–MS/MS method for simultaneous determination of LB-100 and its active metabolite, endothall, in human plasma von Feng, Ye, Massarelli, Erminia, Forman, Eric, Kovach, John S, Salgia, Ravi, Synold, Timothy W

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The Anticancer Activity of a First-in-class Small-molecule Targeting PCNA von Gu, Long, Lingeman, Robert, Yakushijin, Fumiko, Sun, Emily, Cui, Qi, Chao, Jianfei, Hu, Weidong, Li, Hongzhi, Hickey, Robert J, Stark, Jeremy M, Yuan, Yate-Ching, Chen, Yuan, Vonderfecht, Steven L, Synold, Timothy W, Shi, Yanhong, Reckamp, Karen L, Horne, David, Malkas, Linda H

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First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies von Weiss, Glen J., Chao, Joseph, Neidhart, Jeffrey D., Ramanathan, Ramesh K., Bassett, Dawn, Neidhart, James A., Choi, Chung Hang J., Chow, Warren, Chung, Vincent, Forman, Stephen J., Garmey, Edward, Hwang, Jungyeon, Kalinoski, D. Lynn, Koczywas, Marianna, Longmate, Jeffrey, Melton, Roger J., Morgan, Robert, Oliver, Jamie, Peterkin, Joanna J., Ryan, John L., Schluep, Thomas, Synold, Timothy W., Twardowski, Przemyslaw, Davis, Mark E., Yen, Yun

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Development and validation of an LC–MS/MS generic assay platform for small molecule drug bioanalysis von Parise, Robert A., Covey, Joseph M., Hollingshead, Melinda G., Srivastava, Apurva K., Synold, Timothy W., Beumer, Jan H.

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