A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree von TIMMS, Kirsten M, WAGNER, Susanne, SAMUELS, Mark E, FORBEY, Kristian, GOLDFINE, Howard, JAMMULAPATI, Srikanth, SKOLNICK, Mark H, HOPKINS, Paul N, HUNT, Steve C, SHATTUCK, Donna M

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Abstract P1-06-07: Characterization of chromosomal instability in the TNT trial: A randomized phase III trial of carboplatin compared with docetaxel for patients with metastatic or... von Sipos, O, Tovey, H, Quist, J, Haider, S, Nowinski, S, Gazinska, P, Kernaghan, S, Toms, C, Timms, KM, Lanchbury, JS, Linn, SC, Pinder, SE, Bliss, JM, Tutt, A, Cheang, MC, Grigoriadis, A

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Abstract P4-08-06: Impact of molecular subtypes on long-term outcomes in triple-negative breast cancer (TNBC) patients treated with adjuvant AC chemotherapy on SWOG S9313 von Sharma, P, Barlow, WB, Hout, DR, Seitz, RS, Bailey, DB, Godwin, AK, Pathak, H, Timms, KM, Solimeno, C, Linden, HM, Porter, P, Tripathy, D, Hortobagyi, GN, Thompson, A, Pusztai, L, Hayes, DF

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Biomarker assessment of HR deficiency, tumor BRCA1/2 mutations and CCNE1 copy number in ovarian cancer: associations with clinical outcome following platinum monotherapy von Stronach, EA, Paul, J, Timms, KM, Hughes, E, Brown, K, Neff, C, Perry, M, Gutin, A, El-Bahrawy, M, Steel, JH, Liu, X, Lewsley, L-A, Siddiqui, N, Gabra, H, Lanchbury, JS, Brown, R

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Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial von Tutt, A, Tovey, H, Cheang, MCU, Kernaghan, S, Kilburn, L, Gazinska, P, Owen, J, Abraham, J, Barrett, S, Barrett-Lee, P, Brown, R, Chan, S, Dowsett, M, Flanagan, JM, Fox, L, Grigoriadis, A, Gutin, A, Harper-Wynne, C, Hatton, MQ, Hoadley, KA, Parikh, J, Parker, P, Perou, CM, Roylance, R, Shah, V, Shaw, A, Smith, IE, Timms, KM, Wardley, AM, Wilson, G, Gillett, C, Lanchbury, JS, Ashworth, A, Rahman, N, Harries, M, Ellis, P, Pinder, SE, Bliss, JM

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Abstract P6-05-10: Association between BRCA1/2 status and DNA-based assays for homologous recombination deficiency in breast cancer von Timms, KM, Abkevich, V, Neff, C, Morris, B, Potter, J, Tran, TV, Chen, J, Sangale, Z, Tikishvili, E, Zharkikh, A, Perry, M, Gutin, A, Lanchbury, JS

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Molecular and phenotypic variation in patients with severe Hunter syndrome von TIMMS, K. M, BONDESON, M.-L, ALL ANSARI-LARI, M, LAGERSTEDT, K, MUZNY, D. M, DUGAN-ROCHA, S. P, NELSON, D. L, PETTERSSON, U, GIBBS, R. A

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The genomic organization of Isopeptidase T-3 ( ISOT-3), a new member of the ubiquitin specific protease family (UBP) von Timms, K.M, Ansari-Lari, M.A, Morris, W, Brown, S.N, Gibbs, R.A

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Reassessment of biochemically determined Hunter syndrome carrier status by DNA testing von Timms, K M, Edwards, F J, Belmont, J W, Yates, J R, Gibbs, R A

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Improved Ligation-Anchored PCR Strategy for Identification of 5′ Ends of Transcripts von Ansari-Lari, M. Ali, Jones, Stephen N, Timms, Kirsten M, Gibbs, Richard A

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Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes von Hodgson, DR, Dougherty, BA, Lai, Z, Fielding, A, Grinsted, L, Spencer, S, O'Connor, MJ, Ho, TW, Robertson, JD, Lanchbury, JS, Timms, KM, Gutin, A, Orr, M, Jones, H, Gilks, B, Womack, C, Gourley, C, Ledermann, J, Barrett, JC

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Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization von Lheureux, S, Lai, Z, Dougherty, BA, Runswick, S, Hodgson, DR, Timms, KM, Lanchbury, JS, Kaye, S, Gourley, C, Bowtell, D, Kohn, EC, Scott, C, Matulonis, U, Panzarella, T, Karakasis, K, Burnier, JV, Gilks, CB, O'Connor, MJ, Robertson, JD, Ledermann, J, Barrett, JC, Ho, TW, Oza, AM

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Isolation of a rat mitochondrial release factor. Accommodation of the changed genetic code for termination von Lee, C.C., Timms, K.M., Trotman, C.N., Tate, W.P.

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Interaction of the release factors with the Escherichia coli ribosome: structurally and functionally-important domains von Moffat, J.G., Timms, K.M., Trotman, C.N.A., Tate, W.P.

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The ribosomal domain of the bacterial release factors : the carboxyl-terminal domain of the dimer of Escherichia coli ribosomal protein L7/L12 located in the body of the ribosome i... von TATE, W. P, KASTNER, B, EDGAR, C. D, MCCAUGHAN, K. K, TIMMS, K. M, TROTMAN, C. N. A, STOFFLER-MEILICKE, M, STOFFLER, G, NAG, B, TRAUT, R. R

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Prediction of acute myeloid leukaemia risk in healthy individuals von Abelson, S, Collord, G, Ng, SWK, Weissbrod, O, Mendelson Cohen, N, Niemeyer, E, Barda, N, Zuzarte, PC, Heisler, L, Sundaravadanam, Y, Luben, R, Hayat, S, Wang, TT, Zhao, Z, Cirlan, I, Pugh, TJ, Soave, D, Ng, K, Latimer, C, Hardy, C, Raine, K, Jones, D, Hoult, D, Britten, A, McPherson, JD, Johansson, M, Mbabaali, F, Eagles, J, Miller, JK, Pasternack, D, Timms, L, Krzyzanowski, P, Awadalla, P, Costa, R, Segal, E, Bratman, SV, Beer, P, Behjati, S, Martincorena, I, Wang, JCY, Bowles, KM, Quirós, JR, Karakatsani, A, La Vecchia, C, Trichopoulou, A, Salamanca-Fernández, E, Huerta, JM, Barricarte, A, Travis, RC, Tumino, R, Masala, G, Boeing, H, Panico, S, Kaaks, R, Krämer, A, Sieri, S, Riboli, E, Vineis, P, Foll, M, McKay, J, Polidoro, S, Sala, N, Khaw, K-T, Vermeulen, R, Campbell, PJ, Papaemmanuil, E, Minden, MD, Tanay, A, Balicer, RD, Wareham, NJ, Gerstung, M, Dick, JE, Brennan, P, Vassiliou, GS, Shlush, LI

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A time-resolved proteomic and prognostic map of COVID-19 von Demichev, V, Tober-Lau, P, Lemke, O, Nazarenko, T, Thibeault, C, Whitwell, H, Röhl, A, Szyrwiel, L, Ludwig, D, Correia-Melo, C, Aulakh, SK, Helbig, ET, Stubbemann, P, Lippert, LJ, Grüning, N-M, Blyuss, O, White, M, Messner, CB, Joannidis, M, Sonnweber, T, Klein, SJ, Pizzini, A, Sahanic, S, Hilbe, R, Schaefer, B, Machleidt, F, Ruwwe-Glösenkamp, C, Lingscheid, T, Bosquillon de Jarcy, L, Stegemann, MS, Pfeiffer, M, Jürgens, L, Denker, S, Zickler, D, Enghard, P, Zelezniak, A, Campbell, A, Hayward, C, Porteous, DJ, Uhrig, A, Müller-Redetzky, H, Zoller, H, Keller, MA, Tancevski, I, Timms, JF, Zaikin, A, Hippenstiel, S, Ramharter, M, Witzenrath, M, Lilley, K, Mülleder, M, Ralser, M, Kleinschmidt, M, Heim, KM, Meyer-Arndt, L, Hübner, RH, Andermann, T, Opitz, B, Sawitzki, B, Grund, D, Radünzel, P, Schürmann, M, Zoller, T, Alius, F, Knape, P, Breitbart, A, Li, Y, Pergantis, P, Schürmann, D, Temmesfeld-Wollbrück, B, Wendisch, D, Brumhard, S, Haenel, SS, Conrad, C, Georg, P, Kruse, JM, Ferse, C, Spies, C, Weber-Carstens, S, Krannich, A, Zvorc, S, Li, L, Schmidt, S, Rönnefarth, M, Dang-Heine, C, Röhle, R, Lieker, E, Kretzler, L, Wirsching, I, Wollboldt, C, Wu, Y, Schwanitz, G, Hillus, D, Kasper, S, Olk, N, Horn, A, Briesemeister, D, Treue, D, Drosten, C, Von Kalle, C

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Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hep... von WALSH, K. M, TIMMS, P, CAMPBELL, S, MACSWEEN, R. N. M, MORRIS, A. J

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Adaptation and conservation insights from the koala genome von Johnson, RN, Johnson, RN, O’Meally, D, Chen, Z, Etherington, GJ, Etherington, GJ, Ho, SYW, Ho, SYW, Nash, WJ, Nash, WJ, Grueber, CE, Grueber, CE, Cheng, Y, Cheng, Y, Whittington, CM, Dennison, S, Dennison, S, Peel, E, Peel, E, Haerty, W, O’Neill, RJ, Colgan, D, Colgan, D, Russell, TL, Alquezar-Planas, DE, Alquezar-Planas, DE, Attenbrow, V, Attenbrow, V, Bragg, JG, https://orcid.org/0000-0002-7621-7295, Bragg, JG, Brandies, PA, Brandies, PA, Chong, AYY, Chong, AYY, Deakin, JE, Deakin, JE, Di Palma, F, Di Palma, F, Duda, Z, Duda, Z, Eldridge, MDB, Eldridge, MDB, Ewart, KM, Ewart, KM, Hogg, CJ, Hogg, CJ, Frankham, GJ, Frankham, GJ, Georges, A, Georges, A, Gillett, AK, Gillett, AK, Govendir, M, Govendir, M, Greenwood, AD, Greenwood, AD, Hayakawa, T, Hayakawa, T, Helgen, KM, Helgen, KM, Hobbs, M, https://orcid.org/0000-0002-6879-1369, Hobbs, M, Holleley, CE, Heider, TN, Heider, TN, Jones, EA, Jones, EA, King, A, King, A, Madden, D, Madden, D, Graves, JAM, Morris, KM, Morris, KM, Neaves, LE, Neaves, LE, Patel, HR, Patel, HR, Polkinghorne, A, Polkinghorne, A, Renfree, MB, Renfree, MB, Robin, C, Robin, C, Salinas, R, Salinas, R, Tsangaras, K, Tsangaras, K, Waters, PD, Waters, PD, https://orcid.org/0000-0002-4689-8747, Waters, SA, Waters, SA, https://orcid.org/0000-0003-1144-5411, Wright, B, Wright, B, Wilkins, MR, Wilkins, MR, https://orcid.org/0000-0002-5700-5684, Timms, P, Timms, P, Belov, K, Belov, K

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Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the Secretomes of three-dimensional genetic models of ovarian carcinogenesis von Lawrenson, K, Mhawech-Fauceglia, P, Worthington, J, Spindler, TJ, O'Brien, D, Lee, JM, Spain, G, Sharifian, M, Wang, G, Darcy, KM, Pejovic, T, Sowter, H, Timms, JF, Gayther, SA

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