Affimer proteins are versatile and renewable affinity reagents von Tiede, Christian, Bedford, Robert, Heseltine, Sophie J, Smith, Gina, Wijetunga, Imeshi, Ross, Rebecca, AlQallaf, Danah, Roberts, Ashley Pe, Balls, Alexander, Curd, Alistair, Hughes, Ruth E, Martin, Heather, Needham, Sarah R, Zanetti-Domingues, Laura C, Sadigh, Yashar, Peacock, Thomas P, Tang, Anna A, Gibson, Naomi, Kyle, Hannah, Platt, Geoffrey W, Ingram, Nicola, Taylor, Thomas, Coletta, Louise P, Manfield, Iain, Knowles, Margaret, Bell, Sandra, Esteves, Filomena, Maqbool, Azhar, Prasad, Raj K, Drinkhill, Mark, Bon, Robin S, Patel, Vikesh, Goodchild, Sarah A, Martin-Fernandez, Marisa, Owens, Ray J, Nettleship, Joanne E, Webb, Michael E, Harrison, Michael, Lippiat, Jonathan D, Ponnambalam, Sreenivasan, Peckham, Michelle, Smith, Alastair, Ferrigno, Paul Ko, Johnson, Matt, McPherson, Michael J, Tomlinson, Darren Charles

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RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site von Haza, Katarzyna Z., Martin, Heather L., Rao, Ajinkya, Turner, Amy L., Saunders, Sophie E., Petersen, Britta, Tiede, Christian, Tipping, Kevin, Tang, Anna A., Ajayi, Modupe, Taylor, Thomas, Harvey, Maia, Fishwick, Keri M., Adams, Thomas L., Gaule, Thembaninkosi G., Trinh, Chi H., Johnson, Matthew, Breeze, Alexander L., Edwards, Thomas A., McPherson, Michael J., Tomlinson, Darren C.

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Exploiting the Affimer platform against influenza A virus von Debski-Antoniak, Oliver, Flynn, Alex, Klebl, David P, Rojas Rechy, Moisés H, Tiede, Christian, Wilson, Ian A, Muench, Stephen P, Tomlinson, Darren, Fontana, Juan

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Generating and validating renewable affimer protein binding reagents targeting SH2 domains von Heseltine, Sophie J., Billenness, Gregory J., Martin, Heather L, Tiede, Christian, Tang, Anna A.S., Foy, Eleanor, Reddy, Grace, Gibson, Naomi, Johnson, Matt, Webb, Michael E., McPherson, Michael J., Tomlinson, Darren C.

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Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk von King, Rhodri J., Schuett, Katharina, Tiede, Christian, Jankowski, Vera, John, Vicky, Trehan, Abhi, Simmons, Katie, Ponnambalam, Sreenivasan, Storey, Robert F., Fishwick, Colin W. G., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.

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Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics von Adamson, Hope, Nicholl, Amanda, Tiede, Christian, Tang, Anna A, Davidson, Alex, Curd, Helen, Wignall, Alex, Ford, Robert, Nuttall, James, McPherson, Michael J, Johnson, Matt, Tomlinson, Darren C

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Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology von Hughes, David J, Tiede, Christian, Penswick, Natalie, Tang, Anna Ah-San, Trinh, Chi H, Mandal, Upasana, Zajac, Katarzyna Z, Gaule, Thembaninskosi, Howell, Gareth, Edwards, Thomas A, Duan, Jianxin, Feyfant, Eric, McPherson, Michael J, Tomlinson, Darren C, Whitehouse, Adrian

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Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection von Tang, Anna Ah-San, Tiede, Christian, Hughes, David J, McPherson, Michael J, Tomlinson, Darren C

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Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition von Martin, Heather L., Turner, Amy L., Higgins, Julie, Tang, Anna A., Tiede, Christian, Taylor, Thomas, Siripanthong, Sitthinon, Adams, Thomas L., Manfield, Iain W., Bell, Sandra M., Morrison, Ewan E., Bond, Jacquelyn, Trinh, Chi H., Hurst, Carolyn D., Knowles, Margaret A., Bayliss, Richard W., Tomlinson, Darren C.

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Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications von Kearney, Katherine J., Pechlivani, Nikoletta, King, Rhodri, Tiede, Christian, Phoenix, Fladia, Cheah, Ramsah, Macrae, Fraser L., Simmons, Katie J., Manfield, Iain W., Smith, Kerrie A., Spurgeon, Benjamin E.J., Naseem, Khalid M., Ariens, Robert A.S., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.

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Using super-resolution imaging to understand protein organization within Z-discs of striated muscle von Peckham, Michelle, Curd, Alistair, Hughes, Ruth, Martin, Heather, Tang, Anna, Parker, Francine, Tiede, Christian, Tomlinson, Darren

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Affimer reagents as tools in diagnosing plant virus diseases von Hesketh, Emma L., Tiede, Christian, Adamson, Hope, Adams, Thomas L., Byrne, Matthew J., Meshcheriakova, Yulia, Kruse, Inga, McPherson, Michael J., Lomonossoff, George P., Tomlinson, Darren C., Ranson, Neil A.

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Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovascular disease in diabetes von King, Rhodri, Dr, Tiede, Christian, PhD, Simmons, Katie, PhD, Fishwick, Colin, Prof, Tomlinson, Darren, PhD, Ajjan, Ramzi, MD

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Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric... von Alvarez-Rodriguez, Beatriz, Tiede, Christian, Hoste, Alexis C. R., Surtees, Rebecca A., Trinh, Chi, Slack, Gillian S., Chamberlain, John, Hewson, Roger, Fresco, Alba, Sastre, Patricia, Tomlinson, Darren C., Millner, Paul A., Edwards, Thomas A., Barr, John N.

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Affimer reagents enable targeted delivery of therapeutic agents and RNA via virus-like particles von Roberts, Sophie E., Martin, Heather L., Al-Qallaf, Danah, Tang, Anna A., Tiede, Christian, Gaule, Thembaninkosi G., Dobon-Alonso, Albor, Overman, Ross, Shah, Sachin, Peyret, Hadrien, Saunders, Keith, Bon, Robin, Manfield, Iain W., Bell, Sandra M., Lomonossoff, George P., Speirs, Valerie, Tomlinson, Darren C.

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Protein-conjugated microbubbles for the selective targeting of S. aureus biofilms von Caudwell, Jack A., Tinkler, Jordan M., Johnson, Ben R.G., McDowall, Kenneth J., Alsulaimani, Fayez, Tiede, Christian, Tomlinson, Darren C., Freear, Steven, Turnbull, W. Bruce, Evans, Stephen D., Sandoe, Jonathan A.T.

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Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications von Tiede, Christian, Tang, Anna A. S., Deacon, Sarah E., Mandal, Upasana, Nettleship, Joanne E., Owen, Robin L., George, Suja E., Harrison, David J., Owens, Raymond J., Tomlinson, Darren C., McPherson, Michael J.

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Affimer–Enzyme–Inhibitor Switch Sensor for Rapid Wash-free Assays of Multimeric Proteins von Adamson, Hope, Ajayi, Modupe O, Campbell, Emma, Brachi, Erika, Tiede, Christian, Tang, Anna A, Adams, Thomas L, Ford, Robert, Davidson, Alex, Johnson, Matt, McPherson, Michael J, Tomlinson, Darren C, Jeuken, Lars J. C

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Trivalent Gd-DOTA reagents for modification of proteins von Fisher, Martin J, Williamson, Daniel J, Burslem, George M, Plante, Jeffrey P, Manfield, Iain W, Tiede, Christian, Ault, James R, Stockley, Peter G, Plein, Sven, Maqbool, Azhar, Tomlinson, Darren C, Foster, Richard, Warriner, Stuart L, Bon, Robin S

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Sensitive and selective Affimer-functionalised interdigitated electrode-based capacitive biosensor for Her4 protein tumour biomarker detection von Zhurauski, Pavel, Arya, Sunil K., Jolly, Pawan, Tiede, Christian, Tomlinson, Darren C., Ko Ferrigno, Paul, Estrela, Pedro

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