Rational Approaches to Improving Selectivity in Drug Design von Huggins, David J, Sherman, Woody, Tidor, Bruce

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Combined model of intrinsic and extrinsic variability for computational network design with application to synthetic biology von Toni, Tina, Tidor, Bruce

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Computational design of antibody-affinity improvement beyond in vivo maturation von Wittrup, K Dane, Tidor, Bruce, Lippow, Shaun M

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Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution von Zhao, Boyang, Sedlak, Joseph C., Srinivas, Raja, Creixell, Pau, Pritchard, Justin R., Tidor, Bruce, Lauffenburger, Douglas A., Hemann, Michael T.

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Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control von Leonard, Effendi, Ajikumar, Parayil Kumaran, Thayer, Kelly, Xiao, Wen-Hai, Mo, Jeffrey D., Tidor, Bruce, Stephanopoulos, Gregory, Prather, Kristala L. J., Demain, Arnold L.

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MIST: Maximum Information Spanning Trees for dimension reduction of biological data sets von King, Bracken M., Tidor, Bruce

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A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance von Vincent, Benjamin M., Langlois, Jean-Baptiste, Srinivas, Raja, Lancaster, Alex K., Scherz-Shouval, Ruth, Whitesell, Luke, Tidor, Bruce, Buchwald, Stephen L., Lindquist, Susan

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Subsystem identification through dimensionality reduction of large-scale gene expression data von Kim, Philip M, Tidor, Bruce

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Aglycosylated immunoglobulin G₁ variants productively engage activating Fc receptors von Sazinsky, Stephen L, Ott, René G, Silver, Nathaniel W, Tidor, Bruce, Ravetch, Jeffrey V, Wittrup, K. Dane

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Using turnover dynamics to redesign KARI for improved catalytic activity von Karvelis, Elijah, Tidor, Bruce

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A post-synaptic scaffold at the origin of the animal kingdom von Sakarya, Onur, Armstrong, Kathryn A, Adamska, Maja, Adamski, Marcin, Wang, I-Fan, Tidor, Bruce, Degnan, Bernard M, Oakley, Todd H, Kosik, Kenneth S

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Distinct mechanisms act in concert to mediate cell cycle arrest von Toettcher, Jared E, Loewer, Alexander, Ostheimer, Gerard J, Yaffe, Michael B, Tidor, Bruce, Lahav, Galit

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Synergistic drug–cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity von Cosgrove, Benjamin D., King, Bracken M., Hasan, Maya A., Alexopoulos, Leonidas G., Farazi, Paraskevi A., Hendriks, Bart S., Griffith, Linda G., Sorger, Peter K., Tidor, Bruce, Xu, Jinghai J., Lauffenburger, Douglas A.

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Modeling stem cell induction processes von Grácio, Filipe, Cabral, Joaquim, Tidor, Bruce

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A Coarse-Grained Molecular Model for Glycosaminoglycans: Application to Chondroitin, Chondroitin Sulfate, and Hyaluronic Acid von Bathe, Mark, Rutledge, Gregory C., Grodzinsky, Alan J., Tidor, Bruce

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Evaluating the Substrate-Envelope Hypothesis: Structural Analysis of Novel HIV-1 Protease Inhibitors Designed To Be Robust against Drug Resistance von NALAM, Madhavi N. L, ALI, Akbar, RANA, Tariq M, SCHIFFER, Celia A, ALTMAN, Michael D, KIRAN KUMAR REDDY, G. S, CHELLAPPAN, Sripriya, KAIRYS, Visvaldas, ZEN, Ayşegül Ö, HONG CAO, GILSON, Michael K, TIDOR, Bruce

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High-Resolution Protein Design with Backbone Freedom von Harbury, Pehr B., Plecs, Joseph J., Tidor, Bruce, Alber, Tom, Kim, Peter S.

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De novo Determination of Peptide Structure with Solid-State Magic-Angle Spinning NMR Spectroscopy von Rienstra, Chad M., Tucker-Kellogg, Lisa, Jaroniec, Christopher P., Hohwy, Morten, Reif, Bernd, McMahon, Michael T., Tidor, Bruce, Lozano-Pérez, Tomás, Griffin, Robert G.

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Substrate Turnover Dynamics Guide Ketol-Acid Reductoisomerase Redesign for Increased Specific Activity von Karvelis, Elijah, Swanson, Chloe, Tidor, Bruce

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Do salt bridges stabilize proteins? A continuum electrostatic analysis von Hendsch, Zachary S., Tidor, Bruce

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