Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells von Moulding, Dale A., Giles, Richard V., Spiller, David G., White, Michael R. H., Tidd, David M., Edwards, Steven W.

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Improving the Intracellular Delivery and Molecular Efficacy of Antisense Oligonucleotides in Chronic Myeloid Leukemia Cells: A Comparison of Streptolysin-O Permeabilization, Electr... von Spiller, David G., Giles, Richard V., Grzybowski, John, Tidd, David M., Clark, Richard E.

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Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells von Giles, R. V., Spiller, D. G., Grzybowski, J., Clark, R. E., Nicklin, P., Tidd, D. M.

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Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures von Giles, Richard V., Tidd, David M.

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Determination of optimal sites of antisense oligonucleotide cleavage within TNFα mRNA von Lloyd, B. H., Giles, R. V., Spiller, D. G., Grzybowski, J., Tidd, D. M., Sibson, D. R.

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CpG oligodeoxynucleotide 5mer‐induced apoptosis in MOLT‐4 leukaemia cells does not require caspase 3 or new protein synthesis von Tidd, David M., Broughton, Caroline M., Clark, Richard E.

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Oligodeoxynucleotide 5mers containing a 5'-CpG induce apoptosis through a mitochondrial mechanism in T lymphocytic leukaemia cells von Tidd, D M, Spiller, D G, Broughton, C M, Norbury, L C, Clark, R E, Giles, R V

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Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells von Giles, Richard V., Ruddell, Carolyn J., Spiller, David G., Green, John A., Tidd, David M.

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Optimization of Antisense Oligodeoxynucleotide Structure for Targeting bcr-abl mRNA von Giles, R.V., Spiller, D.G., Green, J.A., Clark, R.E., Tidd, D.M.

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Partial protection of oncogene, anti-sense oligodeoxynucleotides against serum nuclease degradation using terminal methylphosphonate groups von Tidd, DM, Warenius, HM

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Clinical use of streptolysin-O to facilitate antisense oligodeoxyribonucleotide delivery for purging autografts in chronic myeloid leukaemia von CLARK, R. E, GRZYBOWSKI, J, BROUGHTON, C. M, PENDER, N. T, SPILLER, D. G, BRAMMER, C. G, GILES, R. V, TIDD, D. M

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Preclinical studies of streptolysin-O in enhancing antisense oligonucleotide uptake in harvests from chronic myeloid leukaemia patients von BROUGHTON, C. M, SPILLER, D. G, PENDER, N, KOMOROVSKAYA, M, GRZYBOWSKI, J, GILES, R. V, TIDD, D. M, CLARK, R. E

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Synthetic oligonucleotides as therapeutic agents von Tidd, DM

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Prospects for Antisense Nucleic Acid Therapy of Cancer and AIDS von Tidd, DM

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Specificity of antisense oligonucleotides von Tidd, David M.

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Identification of a Good C-MYC Antisense Oligodeoxynucleotide Target Site and the Inactivity at This Site of Novel NCH Triplet-Targeting Ribozymes von Giles, Richard V., Spiller, David G., Clark, Richard E., Tidd, David M.

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A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine von Tidd, D M, Paterson, A R

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Abrogation of c-MYC protein degradation in human lymphocyte lysates by prior precipitation with perchloric acid von Spiller, D.G., Tidd, D.M.

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Multigrid Euler calculations over complete aircraft von Tidd, D. M, Strash, D. J, Epstein, B, Luntz, A, Nachshon, A, Rubin, T

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Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA von Giles, R V, Spiller, D G, Clark, R E, Tidd, D M

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