HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain von Tibbs, Gareth R, Rowley, Thomas J, Sanford, R Lea, Herold, Karl F, Proekt, Alex, Hemmings, Jr, Hugh C, Andersen, Olaf S, Goldstein, Peter A, Flood, Pamela D

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Molecular mechanism of cAMP modulation of HCN pacemaker channels von Tibbs, Gareth R, Wainger, Brian J, DeGennaro, Matthew, Santoro, Bina, Siegelbaum, Steven A

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Molecular and Functional Heterogeneity of Hyperpolarization-Activated Pacemaker Channels in the Mouse CNS von Santoro, Bina, Chen, Shan, Luthi, Anita, Pavlidis, Paul, Shumyatsky, Gleb P, Tibbs, Gareth R, Siegelbaum, Steven A

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Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain? von Tibbs, Gareth R, Posson, David J, Goldstein, Peter A

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Identification of a Gene Encoding a Hyperpolarization-Activated Pacemaker Channel of Brain von Santoro, Bina, Liu, David T, Yao, Huan, Bartsch, Dusan, Kandel, Eric R, Siegelbaum, Steven A, Tibbs, Gareth R

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Probucol is anti-hyperalgesic in a mouse peripheral nerve injury model of neuropathic pain von Joyce, Rebecca L., Tibbs, Gareth R., David Warren, J., Costa, Christopher J., Aromolaran, Kelly, Lea Sanford, R., Andersen, Olaf S., Li, Zhucui, Zhang, Guoan, Willis, Dianna E., Goldstein, Peter A.

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cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore von Lyashchenko, Alex K, Redd, Kacy J, Goldstein, Peter A, Tibbs, Gareth R

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Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants von Kim, Elizabeth D., Wu, Xiaoan, Lee, Sangyun, Tibbs, Gareth R., Cunningham, Kevin P., Di Zanni, Eleonora, Perez, Marta E., Goldstein, Peter A., Accardi, Alessio, Larsson, H. Peter, Nimigean, Crina M.

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Perturbation of HCN1 response to small molecule modulation von Kim, Elizabeth D., Falzone, Maria E., Tibbs, Gareth R., Ferrer, Matthew, Goldstein, Peter A., Nimigean, Crina M.

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HCN and K 2P Channels in Anesthetic Mechanisms Research von Riegelhaupt, Paul M, Tibbs, Gareth R, Goldstein, Peter A

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Propofol inhibits HCN1 pacemaker channels by selective association with the closed states of the membrane embedded channel core von Lyashchenko, Alex K., Redd, Kacy J., Yang, Jay, Tibbs, Gareth R.

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An anchor-tether ‘hindered’ HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model von Tibbs, Gareth R., Uprety, Rajendra, Warren, J. David, Beyer, Nicole P., Joyce, Rebecca L., Ferrer, Matthew A., Mellado, Wilfredo, Wong, Victor S.C., Goldberg, David C., Cohen, Melanie W., Costa, Christopher J., Li, Zhucui, Zhang, Guoan, Dephoure, Noah E., Barman, Dipti N., Sun, Delin, Ingólfsson, Helgi I., Sauve, Anthony A., Willis, Dianna E., Goldstein, Peter A.

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The HCN Gene Family: Molecular Basis of the Hyperpolarization-Activated Pacemaker Channels von SANTORO, BINA, TIBBS, GARETH R.

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Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency von Joyce, Rebecca L., Beyer, Nicole P., Vasilopoulos, Georgia, Woll, Kellie A., Hall, Adam C., Eckenhoff, Roderic G., Barman, Dipti N., Warren, J. David, Tibbs, Gareth R., Goldstein, Peter A.

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PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons von Ying, Shui-Wang, Tibbs, Gareth R, Picollo, Alessandra, Abbas, Syed Y, Sanford, R Lea, Accardi, Alessio, Hofmann, Franz, Ludwig, Andreas, Goldstein, Peter A

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HCN Pacemaker Channel Activation Is Controlled by Acidic Lipids Downstream of Diacylglycerol Kinase and Phospholipase A2 von Fogle, Keri J, Lyashchenko, Alex K, Turbendian, Harma K, Tibbs, Gareth R

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Ion binding in the open HCN pacemaker channel pore: fast mechanisms to shape "slow" channels von Lyashchenko, Alex K, Tibbs, Gareth R

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Subunit Stoichiometry of Cyclic Nucleotide-Gated Channels and Effects of Subunit Order on Channel Function von Liu, David T, Tibbs, Gareth R, Siegelbaum, Steven A

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Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring von Rozario, Anjali O., Turbendian, Harma K., Fogle, Keri J., Olivier, Nelson B., Tibbs, Gareth R.

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Probing S4 and S5 segment proximity in mammalian hyperpolarization-activated HCN channels by disulfide bridging and Cd2+ coordination von Bell, Damian C., Turbendian, Harma K., Valley, Matthew T., Zhou, Lei, Riley, John H., Siegelbaum, Steven A., Tibbs, Gareth R.

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