A New Paradigm for KIM-PTP Drug Discovery: Identification of Allosteric Sites with Potential for Selective Inhibition Using Virtual Screening and LEI Analysis von Adams, James, Thornton, Benjamin P., Tabernero, Lydia

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Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence von Scott, Jennifer, Sueiro-Olivares, Monica, Thornton, Benjamin P., Owens, Rebecca A., Muhamadali, Howbeer, Fortune-Grant, Rachael, Thomson, Darren, Thomas, Riba, Hollywood, Katherine, Doyle, Sean, Goodacre, Royston, Tabernero, Lydia, Bignell, Elaine, Amich, Jorge

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Identification of Functional and Druggable Sites in Aspergillus fumigatus Essential Phosphatases by Virtual Screening von Thornton, Benjamin P, Johns, Anna, Al-Shidhani, Reem, Álvarez-Carretero, Sandra, Storer, Isabelle S R, Bromley, Michael J, Tabernero, Lydia

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Revisiting the Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals von Burns, Michael J, Ponting, David J, Foster, Robert S, Thornton, Benjamin P, Romero, Naiffer E, Smith, Graham F, Ashworth, Ian W, Teasdale, Andrew, Simon, Stephanie, Schlingemann, Joerg

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Harmonization of global land use change and management for the period 850–2100 (LUH2) for CMIP6 von Hurtt, George C., Chini, Louise, Sahajpal, Ritvik, Frolking, Steve, Bodirsky, Benjamin L., Calvin, Katherine, Doelman, Jonathan C., Fisk, Justin, Fujimori, Shinichiro, Goldewijk, Kees Klein, Hasegawa, Tomoko, Havlik, Peter, Heinimann, Andreas, Humpenöder, Florian, Jungclaus, Johan, Kaplan, Jed O., Kennedy, Jennifer, Krisztin, Tamás, Lawrence, David, Lawrence, Peter, Ma, Lei, Mertz, Ole, Pongratz, Julia, Popp, Alexander, Poulter, Benjamin, Riahi, Keywan, Shevliakova, Elena, Stehfest, Elke, Thornton, Peter, Tubiello, Francesco N., Vuuren, Detlef P. van, Zhang, Xin

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Livestock and the Environment: What Have We Learned in the Past Decade? von Herrero, Mario, Wirsenius, Stefan, Henderson, Benjamin, Rigolot, Cyrille, Thornton, Philip, Havlík, Petr, de Boer, Imke, Gerber, Pierre

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The Lin28/let-7 Axis Regulates Glucose Metabolism von Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.

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Where does the carbon go? A model–data intercomparison of vegetation carbon allocation and turnover processes at two temperate forest free‐air CO₂ enrichment sites von De Kauwe, Martin G, Medlyn, Belinda E, Zaehle, Sönke, Walker, Anthony P, Dietze, Michael C, Wang, Ying‐Ping, Luo, Yiqi, Jain, Atul K, El‐Masri, Bassil, Hickler, Thomas, Wårlind, David, Weng, Ensheng, Parton, William J, Thornton, Peter E, Wang, Shusen, Prentice, I. Colin, Asao, Shinichi, Smith, Benjamin, McCarthy, Heather R, Iversen, Colleen M, Hanson, Paul J, Warren, Jeffrey M, Oren, Ram, Norby, Richard J

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Endothelial cells express NKG2D ligands and desensitize antitumor NK responses von Thompson, Thornton W, Kim, Alexander Byungsuk, Li, P Jonathan, Wang, Jiaxi, Jackson, Benjamin T, Huang, Kristen Ting Hui, Zhang, Lily, Raulet, David H

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Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma von D’Angelo, Sandra P., Richards, Allison L., Conley, Anthony P., Woo, Hyung Jun, Dickson, Mark A., Gounder, Mrinal, Kelly, Ciara, Keohan, Mary Louise, Movva, Sujana, Thornton, Katherine, Rosenbaum, Evan, Chi, Ping, Nacev, Benjamin, Chan, Jason E., Slotkin, Emily K., Kiesler, Hannah, Adamson, Travis, Ling, Lilan, Rao, Pavitra, Patel, Shreyaskumar, Livingston, Jonathan A., Singer, Samuel, Agaram, Narasimhan P., Antonescu, Cristina R., Koff, Andrew, Erinjeri, Joseph P., Hwang, Sinchun, Qin, Li-Xuan, Donoghue, Mark T. A., Tap, William D.

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Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma von Klemen, Nicholas D, Hwang, Sinchun, Bradic, Martina, Rosenbaum, Evan, Dickson, Mark A, Gounder, Mrinal M, Kelly, Ciara M, Keohan, Mary L, Movva, Sujana, Thornton, Katherine A, Chi, Ping, Nacev, Benjamin A, Chan, Jason E, Bartlett, Edmund K, Richards, Allison L, Singer, Samuel, Donoghue, Mark T A, Tap, William D, D'Angelo, Sandra P

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Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a von Knott, Gavin J, Cress, Brady F, Liu, Jun-Jie, Thornton, Brittney W, Lew, Rachel J, Al-Shayeb, Basem, Rosenberg, Daniel J, Hammel, Michal, Adler, Benjamin A, Lobba, Marco J, Xu, Michael, Arkin, Adam P, Fellmann, Christof, Doudna, Jennifer A

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Genome-wide meta-analyses identify multiple loci associated with smoking behavior von Furberg, Helena, Kim, YunJung, Dackor, Jennifer, Boerwinkle, Eric, Franceschini, Nora, Ardissino, Diego, Bernardinelli, Luisa, Mannucci, Pier M, Mauri, Francesco, Merlini, Piera A, Absher, Devin, Assimes, Themistocles L, tmann, Stephen P, Iribarren, Carlos, Knowles, Joshua W, Quertermous, Thomas, Ferrucci, Luigi, Tanaka, Toshiko, Furberg, Curt D, Haritunians, Talin, McKnight, Barbara, Psaty, Bruce M, Thacker, Evan L, Groop, Leif, Ladenvall, Claes, Boehnke, Michael, Jackson, Anne U, Mohlke, Karen L, Stringham, Heather M, Benjamin, Emelia J, Hwang, Shih-Jen, Levy, Daniel, Preis, Sarah Rosner, Vasan, Ramachandran S, Duan, Jubao, Gejman, Pablo V, Levinson, Douglas F, Sanders, Alan R, Shi, Jianxin, McKay, James D, Agudo, Antonio, Barzan, Luigi, Bencko, Vladimir, Benhamou, Simone, Castellsague, Xavier, Canova, Cristina, Conway, David I, Fabianova, Eleonora, Janout, Vladimir, Holcatova, Ivana, Kjaerheim, Kristina, Lagiou, Pagona, Lissowska, Jolanta, Lowry, Ray, Macfarlane, Tatiana V, Mates, Dana, Richiardi, Lorenzo, Rudnai, Peter, Szeszenia-Dabrowska, Neonilia, Zaridze, David, Znaor, Ariana, Brennan, Paul, Bandinelli, Stefania, Frayling, Timothy M, Guralnik, Jack M, Milaneschi, Yuri, Perry, John R B, Altshuler, David, Elosua, Roberto, Kathiresan, Sek, Lucas, Gavin, Salomaa, Veikko, Schwartz, Stephen M, Voight, Benjamin F, Smit, Johannes H, Vogelzangs, Nicole, Boomsma, Dorret I, de Geus, Eco J C, Vink, Jacqueline M, Willemsen, Gonneke, Gu, Fangyi, Hankinson, Susan E, Hunter, David J, Hofman, Albert, Tiemeier, Henning, van Duijn, Cornelia M, Walter, Stefan, Chasman, Daniel I, Everett, Brendan M, Ridker, Paul M, Li, Ming D, Maes, Hermine H, Audrain-McGovern, Janet, Posthuma, Danielle, Thornton, Laura M, Lerman, Caryn, Kaprio, Jaakko, Rose, Jed E, Lin, Dan-Yu, Sullivan, Patrick F

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Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets von Nacev, Benjamin A., Sanchez-Vega, Francisco, Smith, Shaleigh A., Antonescu, Cristina R., Rosenbaum, Evan, Shi, Hongyu, Tang, Cerise, Socci, Nicholas D., Rana, Satshil, Gularte-Mérida, Rodrigo, Zehir, Ahmet, Gounder, Mrinal M., Bowler, Timothy G., Luthra, Anisha, Jadeja, Bhumika, Okada, Azusa, Strong, Jonathan A., Stoller, Jake, Chan, Jason E., Chi, Ping, D’Angelo, Sandra P., Dickson, Mark A., Kelly, Ciara M., Keohan, Mary Louise, Movva, Sujana, Thornton, Katherine, Meyers, Paul A., Wexler, Leonard H., Slotkin, Emily K., Glade Bender, Julia L., Shukla, Neerav N., Hensley, Martee L., Healey, John H., La Quaglia, Michael P., Alektiar, Kaled M., Crago, Aimee M., Yoon, Sam S., Untch, Brian R., Chiang, Sarah, Agaram, Narasimhan P., Hameed, Meera R., Berger, Michael F., Solit, David B., Schultz, Nikolaus, Ladanyi, Marc, Singer, Samuel, Tap, William D.

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A Multifunctional, Charge‐Neutral, Chiral Octahedral M12L12 Cage von Boer, Stephanie A., White, Keith F., Slater, Benjamin, Emerson, Adrian J., Knowles, Gregory P., Donald, William A., Thornton, Aaron W., Ladewig, Bradley P., Bell, Toby D. M., Hill, Matthew R., Chaffee, Alan L., Abrahams, Brendan F., Turner, David R.

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Secondary source reconfiguration for a Westinghouse four-loop plant von Amiri, Benjamin, Chen, Jianwei

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Forest water use and water use efficiency at elevated CO2: a model-data intercomparison at two contrasting temperate forest FACE sites von De Kauwe, Martin G., Medlyn, Belinda E., Zaehle, Sönke, Walker, Anthony P., Dietze, Michael C., Hickler, Thomas, Jain, Atul K., Luo, Yiqi, Parton, William J., Prentice, I. Colin, Smith, Benjamin, Thornton, Peter E., Wang, Shusen, Wang, Ying-Ping, Wårlind, David, Weng, Ensheng, Crous, Kristine Y., Ellsworth, David S., Hanson, Paul J., Seok Kim, Hyun, Warren, Jeffrey M., Oren, Ram, Norby, Richard J.

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Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States von Rice, Todd W, Rubinson, Lewis, Uyeki, Timothy M, Vaughn, Frances L, John, Benjamin B, Miller, Russell R, Higgs, Elizabeth, Randolph, Adrienne G, Smoot, B Elizabeth, Thompson, B Taylor

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Disentangling climatic and anthropogenic controls on global terrestrial evapotranspiration trends von Mao, Jiafu, Fu, Wenting, Shi, Xiaoying, Ricciuto, Daniel M, Fisher, Joshua B, Dickinson, Robert E, Wei, Yaxing, Shem, Willis, Piao, Shilong, Wang, Kaicun, Schwalm, Christopher R, Tian, Hanqin, Mu, Mingquan, Arain, Altaf, Ciais, Philippe, Cook, Robert, Dai, Yongjiu, Hayes, Daniel, Hoffman, Forrest M, Huang, Maoyi, Huang, Suo, Huntzinger, Deborah N, Ito, Akihiko, Jain, Atul, King, Anthony W, Lei, Huimin, Lu, Chaoqun, Michalak, Anna M, Parazoo, Nicholas, Peng, Changhui, Peng, Shushi, Poulter, Benjamin, Schaefer, Kevin, Jafarov, Elchin, Thornton, Peter E, Wang, Weile, Zeng, Ning, Zeng, Zhenzhong, Zhao, Fang, Zhu, Qiuan, Zhu, Zaichun

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Westinghouse fluence methodology uncertainty estimates for reactor vessel internals fast neutron exposure evaluation in subsequent license renewal period von Chen, Jianwei, Amiri, Benjamin, Geer, Jared

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