Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells von Thompson, Lachlan H, Björklund, Anders

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Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson’s Disease von Gantner, Carlos W., de Luzy, Isabelle R., Kauhausen, Jessica A., Moriarty, Niamh, Niclis, Jonathan C., Bye, Christopher R., Penna, Vanessa, Hunt, Cameron P.J., Ermine, Charlotte M., Pouton, Colin W., Kirik, Deniz, Thompson, Lachlan H., Parish, Clare L.

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A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells von Moriarty, Niamh, Gantner, Carlos W., Hunt, Cameron P.J., Ermine, Charlotte M., Frausin, Stefano, Viventi, Serena, Ovchinnikov, Dmitry A., Kirik, Deniz, Parish, Clare L., Thompson, Lachlan H.

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A Selective, Hydrogel‐Based Prodrug Delivery System Efficiently Activates a Suicide Gene to Remove Undifferentiated Human Stem Cells Within Neural Grafts von Law, Kevin C. L., Mahmoudi, Negar, Zadeh, Zahra E., Williams, Richard. J., Hunt, Cameron P. J., Nagy, Andras, Thompson, Lachlan H., Nisbet, David R., Parish, Clare L.

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Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain von Thompson, Lachlan H., Grealish, Shane, Kirik, Deniz, Björklund, Anders

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Human stem cells harboring a suicide gene improve the safety and standardisation of neural transplants in Parkinsonian rats von de Luzy, Isabelle R., Law, Kevin C. L., Moriarty, Niamh, Hunt, Cameron P. J., Durnall, Jennifer C., Thompson, Lachlan H., Nagy, Andras, Parish, Clare L.

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Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke von Somaa, Fahad A., Wang, Ting-Yi, Niclis, Jonathan C., Bruggeman, Kiara F., Kauhausen, Jessica A., Guo, Haoyao, McDougall, Stuart, Williams, Richard J., Nisbet, David R., Thompson, Lachlan H., Parish, Clare L.

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Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors von Bye, Chris R., Jönsson, Marie E., Björklund, Anders, Parish, Clare L., Thompson, Lachlan H.

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The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease von Grealish, Shane, Jönsson, Marie E., Li, Meng, Kirik, Deniz, Björklund, Anders, Thompson, Lachlan H.

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Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells von Friling, Stina, Andersson, Elisabet, Thompson, Lachlan H, Jönsson, Marie E, Hebsgaard, Josephine B, Nanou, Evanthia, Alekseenko, Zhanna, Marklund, Ulrika, Kjellander, Susanna, Volakakis, Nikolaos, Hovatta, Outi, El Manira, Abdeljabbar, Björklund, Anders, Perlmann, Thomas, Ericson, Johan

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Chondroitinase improves midbrain pathway reconstruction by transplanted dopamine progenitors in Parkinsonian mice von Kauhausen, Jessica A., Thompson, Lachlan H., Parish, Clare L.

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Longitudinal hippocampal volumetric changes in mice following brain infarction von Brait, Vanessa H., Wright, David K., Nategh, Mohsen, Oman, Alexander, Syeda, Warda T., Ermine, Charlotte M., O’Brien, Katrina R., Werden, Emilio, Churilov, Leonid, Johnston, Leigh A., Thompson, Lachlan H., Nithianantharajah, Jess, Jackman, Katherine A., Brodtmann, Amy

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Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms von Cota-Coronado, Agustín, Durnall, Jennifer C, Díaz, Néstor Fabián, Thompson, Lachlan H, Díaz-Martínez, N Emmanuel

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Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice von Kauhausen, Jessica, Thompson, Lachlan H., Parish, Clare L.

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State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons von Basso, Valentina, Döbrössy, Máté D, Thompson, Lachlan H, Kirik, Deniz, Fuller, Heidi R, Gates, Monte A

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Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease von Sahin, Gurdal, Thompson, Lachlan H, Lavisse, Sonia, Ozgur, Merve, Rbah-Vidal, Latifa, Dollé, Frédéric, Hantraye, Philippe, Kirik, Deniz

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An Optimized Protocol for the Generation of Midbrain Dopamine Neurons under Defined Conditions von Gantner, Carlos W., Cota-Coronado, Agustín, Thompson, Lachlan H., Parish, Clare L.

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Embryonic stem cells go from bench to bedside for Parkinson’s disease von Parish, Clare L., Thompson, Lachlan H.

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Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis von Jönsson, Marie E., Ono, Yuichi, Björklund, Anders, Thompson, Lachlan H.

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Histological characterization and quantification of newborn cells in the adult rodent brain von Ermine, Charlotte M., Chavez, Carolina A., Thompson, Lachlan H.

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