microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease von Thome, Aaron D, Harms, Ashley S, Volpicelli-Daley, Laura A, Standaert, David G

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Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease von Thome, Aaron D, Standaert, David G, Harms, Ashley S

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Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease von Williams, Gregory P, Schonhoff, Aubrey M, Jurkuvenaite, Asta, Thome, Aaron D, Standaert, David G, Harms, Ashley S

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α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration von Harms, Ashley S, Delic, Vedad, Thome, Aaron D, Bryant, Nicole, Liu, Zhiyong, Chandra, Sidhanth, Jurkuvenaite, Asta, West, Andrew B

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Functional alterations of myeloid cells during the course of Alzheimer's disease von Thome, Aaron D, Faridar, Alireza, Beers, David R, Thonhoff, Jason R, Zhao, Weihua, Wen, Shixiang, Pascual, Belen, Masdeu, Joseph C, Appel, Stanley H

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Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation von Thome, Aaron D., Thonhoff, Jason R., Zhao, Weihua, Faridar, Alireza, Wang, Jinghong, Beers, David R., Appel, Stanley H.

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Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease von Faridar, Alireza, Vasquez, Matthew, Thome, Aaron D, Yin, Zheng, Xuan, Hui, Wang, Jing Hong, Wen, Shixiang, Li, Xuping, Thonhoff, Jason R, Zhao, Weihua, Zhao, Hong, Beers, David R, Wong, Stephen T C, Masdeu, Joseph C, Appel, Stanley H

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Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease von Thome, Aaron D., Atassi, Farah, Wang, Jinghong, Faridar, Alireza, Zhao, Weihua, Thonhoff, Jason R., Beers, David R., Lai, Eugene C., Appel, Stanley H.

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A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer's disease von Faridar, Alireza, Eid, Abdulmunaim M, Thome, Aaron D, Zhao, Weihua, Beers, David R, Pascual, Maria B, Nakawah, Mohammad O, Roman, Gustavo C, Davis, Charles S, Grundman, Michael, Masdeu, Joseph C, Appel, Stanley H

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The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia von Ponnazhagan, Ranjani, Harms, Ashley S., Thome, Aaron D., Jurkuvenaite, Asta, Gogliotti, Rocco, Niswender, Colleen M., Conn, P. Jeffrey, Standaert, David G.

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Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls von Zhao, Weihua, Beers, David R., Thonhoff, Jason R., Thome, Aaron D., Faridar, Alireza, Wang, Jinghong, Wen, Shixiang, Ornelas, Loren, Sareen, Dhruv, Goodridge, Helen S., Svendsen, Clive N., Appel, Stanley H.

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Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease von Harms, Ashley S., Thome, Aaron D., Yan, Zhaoqi, Schonhoff, Aubrey M., Williams, Gregory P., Li, Xinru, Liu, Yudong, Qin, Hongwei, Benveniste, Etty N., Standaert, David G.

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MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration von Harms, Ashley S, Cao, Shuwen, Rowse, Amber L, Thome, Aaron D, Li, Xinru, Mangieri, Leandra R, Cron, Randy Q, Shacka, John J, Raman, Chander, Standaert, David G

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Serum programmed cell death proteins in amyotrophic lateral sclerosis von Beers, David R., Zhao, Weihua, Thonhoff, Jason R., Faridar, Alireza, Thome, Aaron D., Wen, Shixiang, Wang, Jinghong, Appel, Stanley H.

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Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS von Beers, David R., Thonhoff, Jason R., Faridar, Alireza, Thome, Aaron D., Zhao, Weihua, Wen, Shixiang, Appel, Stanley H.

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Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis von Beers, David R., Zhao, Weihua, Neal, Daniel W., Thonhoff, Jason R., Thome, Aaron D., Faridar, Alireza, Wen, Shixiang, Wang, Jinghong, Appel, Stanley H.

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Restoring regulatory T-cell dysfunction in Alzheimer’s disease through ex vivo expansion von Faridar, Alireza, Thome, Aaron D, Zhao, Weihua, Thonhoff, Jason R, Beers, David R, Pascual, Belen, Masdeu, Joseph C, Appel, Stanley H

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Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis von Thonhoff, Jason R., Berry, James D., Macklin, Eric A., Beers, David R., Mendoza, Patricia A., Zhao, Weihua, Thome, Aaron D., Triolo, Fabio, Moon, James J., Paganoni, Sabrina, Cudkowicz, Merit, Appel, Stanley H.

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A Phase 1 Clinical Trial of IL‐2 in Patients with Alzheimer’s Disease: A Regulatory T Cell Expansion Strategy Targeting Inflammation von Faridar, Alireza, Eid, Abdulmunaim M, Thome, Aaron D, Zhao, Weihua, Beers, David, Pascual, Belen, Nakawah, Mohammad O, Roman, Gustavo C, Davis, Charles S., Grundman, Michael, Masdeu, Joseph C., Appel, Stanley H

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Fractalkine Signaling Regulates the Inflammatory Response in an [alpha]-Synuclein Model of Parkinson Disease von Thome, Aaron D, Standaert, David G, Harms, Ashley S

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